Ralston College presents a lecture by Arif Ahmed on David Hume's conception of self in Book I of his 'Treatise of Human Nature.' The idea of 'the self' or 'soul' as an enduring subject of experience seems very natural, indeed almost inevitable. Hume, however, argues that it is a mistake; and he gives a novel account of what it means for you or me to exist at any one time or across different times. In his lecture, Dr Ahmed assesses Hume's central argument and discusses whether it sheds any light on related questions concerning responsibility, the morality of life and death, and the nature and rationality of 'self-interest.' This lecture and discussion were recorded with a live online audience on May 19th, 2022.