The Six Five with Patrick Moorhead and Daniel Newman

EP 293: AI Factories, Memory Crunch, and the Models vs Infrastructure Showdown


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AI momentum is accelerating, but real-world constraints are tightening. From hyperscaler infrastructure lock-ins and sovereign AI expansion to RAM shortages and enterprise AI pivots, Ep. 293 examines what truly determines leadership in the next phase of AI.

The handpicked topics for this week are:

  1. Meta & NVIDIA's Long-Term AI Infrastructure Partnership: Meta confirmed a deep infrastructure expansion across NVIDIA Blackwell and Rubin GPUs, Grace CPUs, and advanced networking. Pat & Dan discuss hyperscaler AI factories, overflow capacity strategies, and long-term compute commitments.

  2. Microsoft's Global South and Sovereign AI Expansion: As Microsoft continues major investment across India and emerging markets, the hosts explore sovereign cloud strategy, geopolitical positioning, and how global AI infrastructure buildouts shape long-term competitiveness.

  3. California AI Oversight and Regulatory Fragmentation Risk: State-level AI oversight initiatives raise concerns about a patchwork regulatory environment that could slow U.S. innovation relative to centralized global competitors.

  4. The HBM Memory Crunch and Long-Term Supply Constraints: High-Bandwidth Memory shortages continue to shape AI deployment timelines. Relief may not arrive until late this decade, with downstream impacts on data centers, PCs, and consumer devices.

  5. Infosys & Anthropic GSI Pivot to Enterprise AI Agents: Infosys partners with Anthropic to accelerate enterprise AI agent deployment. Hosts examine whether global systems integrators can pivot fast enough in an agent-driven economy.

  6. The Flip – Models vs Infrastructure Leadership: Is AI dominance determined by model quality or infrastructure scale? Pat & Dan debate whether gigawatts or algorithmic efficiency define long-term advantage.

  7. Bulls & Bears – Cyber, Power, EDA, SaaS & AI Infrastructure Plays: Earnings and market signals across Palo Alto Networks, Analog Devices, Cadence, ServiceNow, Dell, and Marvell highlight how execution, supply chains, and capital discipline matter in this cycle.

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The Six Five with Patrick Moorhead and Daniel NewmanBy Patrick Moorhead and Daniel Newman

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