The Six Five with Patrick Moorhead and Daniel Newman

EP 296: GTC Expectations, Copilot's AI Shift, and Apple's Low-CapEx AI Bet


Listen Later

AI is reshaping how software gets built, how infrastructure gets deployed, and how platforms compete for relevance. On Episode 296, Patrick Moorhead and Daniel Newman break down GTC expectations, Microsoft's Anthropic-powered Copilot shift, Adobe's leadership transition, Apple's AI strategy, and the infrastructure debates shaping the next phase of enterprise AI.

The handpicked topics for this week are:

  1. GTC and the Shift to Heterogeneous Compute: NVIDIA heads into GTC with growing pressure to articulate a broader heterogeneous compute strategy. Pat & Dan discuss CPUs, GPUs, inference accelerators, and how future AI workloads will increasingly span training, pre-fill, decode, and agentic workflows.

  2. Why the CPU Is Back in the AI Conversation: As agentic AI expands, CPU demand is moving back into focus. The hosts discuss why CPU-to-GPU ratios are tightening, why this matters for infrastructure planning, and how AI compute is becoming more diversified.

  3. Microsoft's Anthropic-Powered Copilot Shift: Microsoft is leaning harder into model optionality by integrating Anthropic into Copilot workflows. The bigger takeaway is not model preference alone, but Microsoft's distribution advantage, governance layer, and ability to bundle AI functionality directly into the enterprise productivity stack.

  4. The Semantic Layer and the Future of Enterprise Software: Rather than replacing core enterprise systems overnight, AI is increasingly being layered on top of existing platforms. The discussion highlights how enterprise software may evolve through AI wrappers, orchestration, and semantic interfaces rather than a complete replacement.

  5. Adobe's CEO Transition and the AI Narrative Gap: Adobe posted strong numbers, but investor skepticism remains. The conversation centers on whether Adobe failed to clearly articulate its AI upside, whether the market simply remains unconvinced, and why leadership change may reflect the need for a different kind of AI-era storytelling.

  6. Grid Underutilization and the Energy Debate: Google, Tesla, and others are backing a lobbying effort focused on grid underutilization. The hosts unpack why this matters for hyperscalers, data center growth, and the broader push to use energy infrastructure more intelligently before simply adding more capacity.

  7. The Flip: Has Apple Found a Way to Win Without Massive AI CapEx? In this week's debate, Patrick argues Apple may have found a differentiated path by focusing on device-level inference, silicon efficiency, and distribution across its installed base. Daniel pushes back, arguing that if intelligence becomes platform agnostic, Apple risks becoming just another hardware endpoint with a limited moat at the AI layer.

  8. HPE's Networking-Led Enterprise AI Positioning: HPE's results reinforced the strategic value of networking as a differentiation layer. The Juniper acquisition, enterprise focus, and higher-margin infrastructure strategy continue to distinguish HPE from peers chasing hyperscale AI server volumes.

  9. Oracle's OCI Momentum and the Fungibility of Compute: Oracle delivered the "show me" quarter investors wanted, driven by OCI growth and backlog expansion. The hosts argue that if Oracle builds the capacity, the compute will get used, regardless of which model provider ultimately occupies it.

  10. Adobe, TSMC, and ASML as Signals of the Next AI Buildout: From Adobe's forward-looking market pressure to TSMC's continued growth and ASML's move into advanced packaging, the conversation closes on what these indicators say about demand durability, capital discipline, and the future of semiconductor infrastructure.

For a deeper dive into each topic, please click on the provided links. Subscribe to our YouTube Channel so you never miss an episode.

The Decode

Nvidia Expands AI Infrastructure Ecosystem https://www.cnbc.com/2026/03/09/nscale-ai-data-center-nvidia-raise.html https://x.com/PatrickMoorhead/status/2031039275861455314?s=20 NVIDIA and Thinking Machines Lab Announce Long-Term Gigawatt-Scale Strategic Partnership https://blogs.nvidia.com/blog/nvidia-thinking-machines-lab/ https://techcrunch.com/2026/03/10/thinking-machines-lab-inks-massive-compute-deal-with-nvidia/ Microsoft 365 Copilot Wave 3 – Turning Copilot from add-on into stack strategy https://x.com/PatrickMoorhead/status/2031072488059449701 https://x.com/danielnewmanUV/status/2031016955549716542 Microsoft CEO Satya Nadella praises outgoing Adobe CEO Shantanu Narayen's 'legendary run' at digital media company https://economictimes.indiatimes.com/tech/technology/microsoft-ceo-satya-nadella-praises-outgoing-adobe-ceo-shantanu-narayens-legendary-run-at-digital-media-company/articleshow/129541308.cms Google, Tesla, and data center developer Verrus are among a group of companies arguing that the electrical grid is being underutilized https://techcrunch.com/2026/03/10/google-and-tesla-think-were-managing-the-electrical-grid-all-wrong/ The Flip: Has Apple Found a Way to Win Without Massive AI CapEx? Perplexity Computer to Run on Mac Desktop Computers & iOS https://x.com/danielnewmanUV/status/2031841884822229340?s=20

https://x.com/PatrickMoorhead/status/2031825606313119750?s=20 https://x.com/PatrickMoorhead/status/2032276716786221113?s=20 Bulls & Bears

HPE Q1 Earnings

https://www.hpe.com/us/en/newsroom/press-release/2026/03/hpe-reports-fiscal-2026-first-quarter-results.html

https://x.com/danielnewmanUV/status/2031132577256403050?s=20

https://x.com/PatrickMoorhead/status/2031109683717747160

Oracle Q3 Earnings

https://finance.yahoo.com/news/oracle-stock-rockets-higher-on-q3-earnings-beat-2027-revenue-outlook-201151427.html

https://x.com/PatrickMoorhead/status/2031502202766766104

https://x.com/danielnewmanUV/status/2031518677242147087

TSMC Earnings (Jan-Feb revenue rose 30%)

https://pr.tsmc.com/english/news/3290

https://seekingalpha.com/news/4562561-tsmc-jan-feb-revenue-rises-30-amid-strong-global-ai-demand

Adobe Q1 Earnings

https://www.businesswire.com/news/home/20260312749997/en/Adobe-Delivers-Record-Q1-Results

https://news.adobe.com/news/2026/03/adobe-q1fy26-financial-results

UiPath Earnings

https://www.investing.com/news/earnings/uipath-forecasts-full-year-revenue-above-expectations-stock-seesaws-after-hours-4555553

https://ir.uipath.com/news/detail/431/uipath-reports-fourth-quarter-and-full-year-fiscal-2026-financial-results

Rubrik Earnings

https://www.investors.com/news/technology/rubrik-stock-rbrk-rubrik-earnings-q42025/

https://ir.rubrik.com/financials/quarterly-results/default.aspx

SentinelOne Earnings

https://www.investors.com/news/technology/sentinelone-stock-s-sentinelone-earnngs-news-q42025/

...more
View all episodesView all episodes
Download on the App Store

The Six Five with Patrick Moorhead and Daniel NewmanBy Patrick Moorhead and Daniel Newman

  • 3.9
  • 3.9
  • 3.9
  • 3.9
  • 3.9

3.9

11 ratings


More shows like The Six Five with Patrick Moorhead and Daniel Newman

View all
This Week in Startups by Jason Calacanis

This Week in Startups

1,296 Listeners

The Twenty Minute VC (20VC): Venture Capital | Startup Funding | The Pitch by Harry Stebbings

The Twenty Minute VC (20VC): Venture Capital | Startup Funding | The Pitch

536 Listeners

WSJ Tech News Briefing by The Wall Street Journal

WSJ Tech News Briefing

1,649 Listeners

The a16z Show by Andreessen Horowitz

The a16z Show

1,105 Listeners

Invest Like the Best with Patrick O'Shaughnessy by Colossus | Investing & Business Podcasts

Invest Like the Best with Patrick O'Shaughnessy

2,342 Listeners

NVIDIA AI Podcast by NVIDIA

NVIDIA AI Podcast

343 Listeners

All-In with Chamath, Jason, Sacks & Friedberg by All-In Podcast, LLC

All-In with Chamath, Jason, Sacks & Friedberg

10,254 Listeners

Dwarkesh Podcast by Dwarkesh Patel

Dwarkesh Podcast

551 Listeners

Big Technology Podcast by Alex Kantrowitz

Big Technology Podcast

512 Listeners

The Big Take by Bloomberg

The Big Take

155 Listeners

Moonshots with Peter Diamandis by PHD Ventures

Moonshots with Peter Diamandis

602 Listeners

Bloomberg Tech by Bloomberg

Bloomberg Tech

69 Listeners

The AI Daily Brief: Artificial Intelligence News and Analysis by Nathaniel Whittemore

The AI Daily Brief: Artificial Intelligence News and Analysis

688 Listeners

Sharp Tech with Ben Thompson by Andrew Sharp and Ben Thompson

Sharp Tech with Ben Thompson

97 Listeners

TBPN by John Coogan & Jordi Hays

TBPN

140 Listeners