In this episode of The Back Table MSK Podcast, Dr. Alexa Levey discusses the importance of multidisciplinary treatment planning for sarcomas with Dr. Yvette Ho and Dr. Jessica Jones.

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Stryker Interventional Spine

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SYNPOSIS

The conversation explores the necessity of a multidisciplinary approach and the challenges associated with managing both osseous and soft tissue sarcomas. Dr. Jones highlights recent advancements in precision medicine, including a novel drug, nirogacesta, for desmoid tumors. Dr. Ho addresses common misconceptions surrounding desmoid tumors, emphasizing their potential for significant tissue destruction, and shares insights from her experience in limb salvage surgery. Dr. Levey discusses the considerations involved in needle biopsy and presents case studies where cryoablation effectively reduced desmoid tumor sizes.

The doctors also discuss strategies for managing nociceptive and mechanical pain, such as intrathecal pain pumps, radiation therapy, and kyphoplasty.

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TIMESTAMPS

00:00 - Introduction

03:51 - Challenges in Sarcoma Management

13:06 - Precision Medicine in Treatment Planning

16:44 - The Role of Biopsy

20:51 - The Importance of Specialized Oncology Care

25:13 - Collaboration Throughout Treatment Course

31:03 - Cryoablation and Case Studies

35:13 - New Drug Development for Desmoid Tumors

39:06 - Limb Salvage Considerations

41:13 - Metastasis, Recurrence, and Pain Management

49:57 - Final Thoughts

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RESOURCES

OGSIVEO (Nirogacestat):

https://www.ogsiveo.com/