Notes:

NP03, a Microdose Lithium Formulation, Blunts Early Amyloid Post-Plaque Neuropathology in McGill-R-Thy1-APP Alzheimer-Like Transgenic Rats: https://content.iospress.com/articles/journal-of-alzheimers-disease/jad190862

Can lithium halt progression of Alzheimer's disease?: https://www.sciencedaily.com/releases/2020/01/200125090727.htm

Microdose Lithium Treatment Reduced Inflammatory Factors and Neurodegeneration in Organotypic Hippocampal Culture of Old SAMP-8 Mice: https://pubmed.ncbi.nlm.nih.gov/32642922/

Low-dose Lithium treatment for agitation and psychosis in Alzheimer’s disease and Frontotemporal dementia: A case series: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5322244/

Lithium Orotate Stops Alzheimers: https://beforeitsnews.com/eu/2012/12/lithium-orotate-stops-alzheimers-2488838.html?utm_source=dlvr.it&utm_medium=twitter

Lithium Orotate Risks: https://www.superfoodly.com/lithium-orotate/

On the Physiological function of lithium from a psychiatric viewpoint:

https://pubmed.ncbi.nlm.nih.gov/11601880/

The Faces of Mania: The Legacy of Athanasios Koukopoulos:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5405619/

The History of Lithium Therapy: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3712976/

History of the Introduction of Lithium into Medicine and Psychiatry:

http://inhn.org/books/books/johan-schioldann-history-of-the-introduction-of-lithium-into-medicine-and-psychiatry-birth-of-modern-psychopharmacology-1949-reviewed-by-barry-blackwell.html

Lithium increases N-acetyl-aspartate in the human brain:

https://pubmed.ncbi.nlm.nih.gov/10913502/

N-acetylaspartate concentration in corpus callosum is positively correlated with intelligence in adolescents: https://pubmed.ncbi.nlm.nih.gov/21983183/

A Role in Neuroprotection against N-methyl-D-aspartate receptor-mediated excitotoxicity https://www.sciencedirect.com/science/article/pii/S0014579303001674

Neuroplasticity via glycogen synthase kinase-3beta, beta-catenin, and neurotrophin cascades: https://pubmed.ncbi.nlm.nih.gov/19423950/

Lithium at 50: Have the neuroprotective effects of this unique cation been overlooked?: https://pubmed.ncbi.nlm.nih.gov/10509176/

Lithium in drinking water and the incidences of crimes, suicides, and arrests related to drug addictions: https://pubmed.ncbi.nlm.nih.gov/1699579/

Lithium orotate in the treatment of alcoholism and related conditions:

https://pubmed.ncbi.nlm.nih.gov/3718672/

Reduced Serotonin Reuptake Transporter (SERT) Function Causes Insulin Resistance and Hepatic Steatosis Independent of Food Intake:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3297606/

Medications for Mental Health Treatment: https://dualdiagnosis.org/mental-health-and-addiction/medications/

Long-Term Lithium Treatment Causes Serotonin Receptor Down-Regulation via Serotonergic Presynapses in Rat Brain:

https://www.karger.com/Article/PDF/118292

Mutation links bipolar disorder to mitochondrial disease:

https://www.eurekalert.org/pub_releases/2018-06/r-mlb060818.php

Ant1 mutant mice bridge the mitochondrial and serotonergic dysfunctions in bipolar disorder: https://www.nature.com/articles/s41380-018-0074-9

Dietary amino acids and brain function: https://pubmed.ncbi.nlm.nih.gov/7903674/

Research explains lithium’s dual anti-manic/ anti-depressive effect:

https://news.wisc.edu/research-explains-lithiums-dual-anti-manic-anti-depressive-effect/

Orotic Acid: Why it is Important to Understand Its Role in Metabolism:

https://www.omicsonline.org/open-access/orotic-acid-why-it-is-important-to-understand-its-role-in-metabolism-2168-9652-1000e157.php?aid=90853

Nutritional therapies for mental disorders:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2248201/

Products:

Lithium Orotate: https://amzn.to/2XKCgVd

Lithia Water(Lithium Chloride): https://amzn.to/33HBufz

Ionic Lithium (Lithium Chloride): https://amzn.to/33JtFWz

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