Vertebral augmentation for degenerative disc disease has traditionally been performed using cement injections. However, new biomaterials are emerging that may offer more precise targeting of the vertebral discs, potentially leading to higher patient satisfaction. In this episode of Backtable MSK, Dr. Olivier Clerk-Lamalice discusses significant advances in the treatment of degenerative disc disease, with a particular focus on disc augmentation using intradiscal hydrogel. This episode marks the third and final installment in our series on degenerative disc disease with Dr. Clerk-Lamalice.

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This podcast is supported by:

Medtronic Interventional

https://www.medtronic.com/interventional

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SYNPOSIS

Dr. Clerk-Lamalice begins by exploring the history of hydrogel use for degenerative disc disease, highlighting the different iterations of this biomaterial. As an experienced practitioner in this field, he shares valuable tips on injection volume and technique. His work is especially meaningful to him because the procedure provides significant pain relief for patients. The doctors also delve into patient selection criteria and ongoing clinical trials aimed at obtaining FDA approval in North America. Additionally, the episode offers a preview of the upcoming GRIBOI conference, which will focus on the use of injectable osteoarticular biomaterials in bone augmentation.

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TIMESTAMPS

00:00 - Introduction

02:28 - History and Current Use of Intradiscal Hydrogel

07:19 - Technical Insights for Injection

12:51 - Clinical Outcomes and Patient Satisfaction

15:33 - Ongoing FDA Clinical Trials

16:38 - Future Research and GRIBOI Conference Details

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RESOURCES

BackTable MSK Ep. 67- Introduction to the Treatment of Discogenic Back Pain:

https://www.backtable.com/shows/msk/podcasts/67/introduction-to-treatment-of-discogenic-back-pain

BackTable MSK Ep. 68- BackTable Basics: Lumbar Access and Discography

https://www.backtable.com/shows/msk/podcasts/68/backtable-basics-lumbar-disc-access-discography

GRIBOI Conference:

https://www.griboi.org/annualconference

Hydrogel Augmentation of the Lumbar Intervertebral Disc: An Early Feasibility Study of a Treatment for Discogenic Low Back Pain (Beal et al, 2024):

https://www.jvir.org/article/S1051-0443(23)00694-2/fulltext