In this episode, Dr. Kirk Barber sits down with Dr. Jensen Yeung to discuss his recent evidence-based review on the use of systemic JAK inhibitors in chronic prurigo and prurigo nodularis (PN).

They explore:

• Why PN remains underdiagnosed and profoundly life-altering
• The limitations of traditional therapies and the gap in approved treatments
• How rapid itch reduction with JAK inhibitors, often within days, may change clinical practice
• Case insights, durability of response, and the evolving therapeutic landscape
• Where JAK inhibitors may fit within current guidelines and future topical options

Dr. Yeung also shares how patient experiences inspire his research and why PN management is entering a more hopeful era.

Article discussed: Management of Chronic Prurigo and Prurigo Nodularis With Systemic JAK Inhibitors, JCMS (Sept–Oct 2025).

Available open access for three weeks after episode release.

Dr. Jensen Yeung is an Associate Professor of Dermatology at the University of Toronto and Medical Director of the Phototherapy Education and Research Centre (PERC) at Women’s College Hospital. He leads specialty clinics focused on psoriasis, phototherapy, skin of color, and complex inflammatory dermatoses. 

Dr. Barber and his guests do not receive any financial reimbursement for the production of this podcast.

For more great CDA podcasts check out Dermalogues, our Residents podcast hosted by Dr Kerri Purdy.

To learn more about the work of the Canadian Dermatology Association, please visit our website at dermatology.ca

This podcast is produced by David McGuffin, and Clare and Graham McGuffin of ExploreProductions.ca