Commissioned in 1516, four years before Raphael's premature death at the age of 37, by Cardinal Giulio de' Medici, the "Transfiguration" was Raphael's last great altarpiece. The painting is a sort of summation of Raphael's artistic evolution, and not only synthesizes the artistic styles of Leonardo da Vinci and Michelangelo, but is also a harbinger of the Tenebrist style of Caravaggio nearly a century later.