Dr. Audrey DeClue and Dr. Daniella Vansteenkiste discuss recognizing and managing nerve pain and neuropathy in sport horses. Dr. Vansteenkiste emphasizes the importance of understanding subtle clinical signs like behavioral changes, sweat patterns, and postural alterations. She explains the complexities of nerve pain, including the concept of "wind-up" and the slow healing rate of nerves, which can take weeks to months. They highlight the need for multimodal treatment approaches such as pain management strategies and stress the importance of early detection and long-term management rather than quick fixes. The conversation underscores the necessity of veterinarians and horse owners being aware of the chronic nature of nerve pain and its impact on horse welfare.