The Top Line

ESMO, WCLC lung cancer data spark hope—and debate


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At the recent World Conference on Lung Cancer and European Society for Medical Oncology annual meetings, two packages of lung cancer data from a partnership between Akeso and Summit Therapeutics and another collaboration between iTeos Therapeutics and GSK showed much promise of disrupting the current standard of care. But they also drew some questions and debate. 

In this week's episode of “The Top Line,” Angus Liu from Fierce Pharma and Gabrielle Masson from Fierce Biotech discuss the key issues behind those two readouts.   

To learn more about the topic in this episode: 

  • iTeos-GSK's TIGIT combo shows 30% more tumor shrinkage than Jemperli, but safety signals scare investors
  • Akeso, Summit's PD-1 bispecific crushes Merck's Keytruda in study, signaling potential new standard in lung cancer
  • 'Cooking with gas': Regeneron sees its Opdualag rival as next big thing for treating solid tumors
  • ESMO: Bristol Myers moves Opdualag into phase 3 trials in competitive first-line lung cancer field

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