In this episode of "In the Interim," Berry's Director of Software, Tom Parke, takes us into the fascinating realm of clinical trial simulation. With Tom joining from the UK, we discuss the intricacies and updates surrounding FACTS, a sophisticated clinical trial simulation software. Learn about its significance in designing adaptive trial designs and its latest enhancements with the release of FACTS 7.1. Discover the balance between expanding features and maintaining user simplicity, ensuring that both Berry Consultants and external users can innovate effectively.

Key Highlights:
• Introduction of FACTS 7.1, emphasizing enhancements in code quality and simulation capabilities.
• Discussion on the history and evolution of clinical trial simulators at Berry Consultants.
• Exploration of FACTS' new features, such as Bayesian predictive probabilities and phase one dose escalation improvements.
• Insight into the challenges of creating user-friendly software with extensive features for trial simulation.
• Plans for future developments, including wizards and enhanced design comparison tools.

Quotes:
• "FACTS turns trial design and statistics into a game—where you can explore and try different options." – Tom Parke
• "You're creating software that allows exploring designs you can't calculate an answer to." – Tom Parke
• "It's all about making sure the designers have the right tools to efficiently explore different trial designs." – Scott Berry