In this month's Fertility & Sterility: Unplugged, we take a look at articles from F&S's sister journals! Topics this month include: (03:00) prevalence of endometrial hyperplasia and carcinoma among patients with PCOS; differences in trophectoderm gene expression among euploid blasts during extended in vitro culture (13:16), comparison of embryo transfer techniques and pregnancy outcomes (28:58), and exploring the association of ectopic pregnancy with embryonic competence (39:19).

F&S Reports: https://www.fertstertreports.org/article/S2666-3341(25)00101-1/fulltext F&S Science: https://www.fertstertscience.org/article/S2666-335X(25)00067-9/abstract F&S Reviews: https://www.fertstertreviews.org/article/S2666-5719(25)00002-7/fulltext Consider this: https://www.fertstert.org/news-do/beyond-tubal-factors-rethinking-ectopic-pregnancy-through-embryonic-competence-and

View the sister journals at:

• https://www.fertstertreviews.org
• https://www.fertstertreports.org
• https://www.fertstertscience.org

Fertility & Sterility on Air discusses ASRM INNOVATE, a reproductive health innovation summit that brings together dynamic healthcare professionals, thought leaders, and innovators to forge advancements in reproductive medicine through the synergy of science and technology. Join our host Kate Devine with Jared Robins, Anuja Dokras, and David Sable as they talk about formulating and executing the inaugural ASRM INNOVATE conference dedicated to identifying and addressing gaps and lack of innovation within the field of reproductive medicine by cultivating deliberate collaboration and exchange of ideas between healthcare professionals, innovators, and investors.

View Fertility and Sterility at https://www.fertstert.org/

Fertility & Sterility on Air is at the American Association of Gynecologic Laparoscopists 2025 Global Congress! In this episode, our host Pietro Bortoletto conducts a roundtable with expert reproductive surgeons Rebecca Flyckt, Zaraq Khan, and Michael Neblett on the surgical and medical management of adenomyosis with emphasis on diagnosis, innovative medical therapies, and uterus-sparing surgical techniques designed to optimize fertility outcomes.

View Fertility and Sterility at https://www.fertstert.org/

Take a sneak peek at this month's Fertility and Sterility! Articles discussed this month are:

Articles: 1. The reproductive journey of women with obesity undergoing assisted reproductive technology: an analysis of 48,595 in vitro fertilization cycles in 31,829 women

2. The reproductive endocrinology and infertility subspecialist: definition, training, and scope of practice in the United States

3. Clinical outcomes in patient-oriented strategies encompassing individualized oocyte number (POSEIDON) low-prognosis patients receiving in vitro fertilization / intracytoplasmic sperm injection treatment: a multi-center retrospective cohort study\

4. Gonadotropin-releasing hormone antagonist protocol is associated with higher oocyte yield in young women at high risk for low oocyte retrieval: a retrospective study using three statistical methods

5. Outcomes of in vitro fertilization cycles with embryo donation compared with double gamete donation with cryopreserved donor oocytes

6. Leveraging anti-Müllerian hormone and metaphase II oocyte yield to improve counseling for oocyte cryopreservation outcomes

7. Effect of a one-step fast warming protocol on reproductive outcomes of vitrified-warmed blastocysts

View the December 2025, Volume 124 Issue 6 of Fertility and Sterility at https://www.fertstert.org/issue/S0015-0282(25)X0013-3

View Fertility and Sterility at https://www.fertstert.org/

Welcome to Fertility & Sterility Roundtable! Each week, we will host a discussion with the authors of "Views and Reviews" and "Fertile Battle" articles published in a recent issue of Fertility & Sterility.

This week, we welcome Dr. Richard Paulson and Dr. Jamie Kuhlman to discuss Restorative Reproductive Medicine (RRM) — a field that describes itself as focusing on identifying and treating the root causes of infertility rather than bypassing or suppressing natural reproductive processes. In this episode, we explore whether RRM represents a truly novel approach to fertility care, examine its religious and political influences, and consider the potential risks the movement poses to access to evidence-based fertility treatments, including IVF.

Dr. Richard Paulson holds the Alia Tutor Chair in Reproductive Medicine and is Professor and vice-chair in the Department of Obstetrics and Gynecology at the University of Southern California, where he is also Director of the Fellowship in Reproductive Endocrinology and Infertility. He is past president of the American Society for Reproductive Medicine, and of the Pacific Coast Reproductive Society. Dr. Paulson has authored over 300 scientific articles and has received more than 35 awards for research and scientific presentations. He is the current Editor-in-Chief of "Fertility & Sterility Reports."

Dr. Kuhlman is a Licensed Psychologist and the Owner of Courageous Path Counseling, PLLC, in Nashville, TN. She specializes in infertility, postpartum, and maternal mental health through individual counseling and psychological evaluations for third-party reproduction. She is also a PRIMED Scholar with the American Society of Reproductive Medicine, focusing on advocacy within reproductive healthcare.

The unscientific nature of the arguments of "Restorative Reproductive Medicine" and why we need to understand them https://www.fertstertreports.org/article/S2666-3341(25)00111-4/fulltext

The illusion of reproductive choice: how restorative reproductive medicine violates reproductive autonomy and informed consent https://www.fertstert.org/article/S0015-0282(25)00596-5/fulltext

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Fertility & Sterility on Air is at the 2025 ASRM Scientific Congress & Expo in San Antonio, Texas (Part 3)! In this episode, our hosts Pietro Bortoletto, Blake Evans, Eve Feinberg, and Richard Paulson cover:

• Advancing ICSI robotics: follow up on the transition from remote to fully automated intracytoplasmic sperm injection with Gerardo Mendizabal (01:06)
• Overcoming challenges in ovarian visualization: a case report of a magnetic resonance imaging-guided oocyte retrieval resulting in live birth with Samir Babayev (11:02)
• Early pregnancy RhD-immune globulin practice patterns among REI physicians and the need for ASRM guidelines for RhIG administration with Nimerta Sandhu (20:30)
• At-home and mail-in semen analysis: a critical review of scientific validation, regulatory oversight, and marketing claims with Juan Varela (25:00)
• Preliminary analysis of a prospective cohort study of an epigenetic sperm quality test ("SpermQT") to predict success rates of ovarian stimulation treatment with Cassandra Roeca (31:05)
• A discussion with the 2025 Ira and Ester Rosenwaks New Investigator Award recipient, Min Yang (34:50)
• How combining medicine and coaching can empower patients through their fertility journey with Erica Bove (43:45)

View Fertility and Sterility at https://www.fertstert.org/

Fertility & Sterility on Air is at the 2025 ASRM Scientific Congress & Expo in San Antonio, Texas (Part 2)! In this episode, our hosts Kate Devine and Eve Feinberg cover:

• The impact of cannabis on reproductive health with Jason Hedges and Jamie Lo (01:06) Anti-Müllerian Hormone (AMH) as a therapeutic target in women's health with David Pépin (10:18)
• A discussion with the 2025 ASRM Distinguished Researcher Award recipient, Denny Sakkas (18:32)
• Outcomes for patients who underwent oocyte cryopreservation at age 35 years and older: results from a large, multi-center cohort with Michelle Bayefsky (26:10)
• The SLEEP Study: Sleep length and euploid embryo transfer protocol using the Oura Ring to assess the effect of sleep parameters on transfer outcomes with Sarah Cromack (33:48)
• Investigating the reproductive potential of non-mosaic segmental aneuploidy: a double-blinded, multicenter non-selection study of 176 single frozen embryo transfers with Stephanie Willson and Emily Mounts (44:08)

View Fertility and Sterility at https://www.fertstert.org/

Fertility & Sterility on Air is at the 2025 ASRM Scientific Congress & Expo in San Antonio, Texas (Part 1)! In this episode, our hosts Kate Devine, Blake Evans, and Micah Hill cover:

• Anne Steiner, the current Editor-in-Chief of F&S Reviews, and Ruben Alvero, the incoming Editor-in-Chief, discuss the journal's submission process and future directions (01:06)
• Complexity of genetics and available testing modalities with Mili Thakur (06:45)
• Optimizing embryo utilization: cost effectiveness of cryopreservation in the face of legal and financial uncertainty with Allison Eubanks (16:25)
• Optimizing pain control following oocyte retrieval - a randomized blinded placebo controlled trial assessing ketorolac efficacy and fresh embryo transfer outcomes with Marja Brolinson King and Laura Zalles (21:42)
• Discussing the Fertility and Sterility Editorial Fellowship program with F&S's first Editorial Fellow, Allison Eubanks (30:22)
• Beyond expert grading: comparing a fully automated AI system to five expert embryologists for embryo selection with Mohsen Bahrami (36:20)

View Fertility and Sterility at https://www.fertstert.org/

Take a sneak peek at this month's Fertility and Sterility! Articles discussed this month are:

(03:03) A Randomized Controlled Trial of Counseling and Educational methods on Preimplantation Genetic Testing for Aneuploidy (PGT-A) for in vitro fertilization (IVF) patients

(14:02) Healthy euploid dizygotic twin birth after transfer of non-mosaic aneuploid embryos

(25:05) Validity of completely omitting endocrine and ultrasound monitoring in hormone replacement therapy protocols for frozen embryo transfer in good-prognosis patients undergoing single blastocyst transfer

(38:52) Cost-effectiveness of single euploid frozen embryo transfer in a true natural versus a hormonal replacement cycle

(44:29) Modified Versions of Natural Frozen Embryo Transfers Do Not Impact Live Births

(55:28) Soy consumption and the risk of laparoscopically confirmed endometriosis in a prospective cohort study

(01:02:42) Optimizing In Vitro Maturation Outcomes of Oocytes Following Gonadotropin Priming in Premenarcheal Girls Undergoing Ovarian Tissue Cryopreservation

View the November 2025, Volume 124 Issue 5 of Fertility and Sterility at https://www.fertstert.org/issue/S0015-0282(25)X0012-1

View Fertility and Sterility at https://www.fertstert.org/

Welcome to Fertility & Sterility Roundtable! Each month, we will host a discussion with the authors of "Views and Reviews" and "Fertile Battle" articles published in a recent issue of Fertility & Sterility.

This month, we welcome Dr. Brian Levine and Dr. Kate Schoyer to discuss if physicians should be facilitating gestational carrier arrangements in the absence of a medical indication, also known as elective surrogacy.

Dr. Brian Levine is the founding partner and practice director of CCRM New York, where he has helped countless families on their path to parenthood. Dr. Levine is also the founder of Nodal, the premier online gestational surrogacy platform, which connects intended parents and surrogates in a trusted and transparent way.

Dr. Kate Schoyer is an Associate Professor of Obstetrics and Gynecology and Reproductive Endocrinology and Infertility at the Medical College of Wisconsin. She is the Director of the Division of Reproductive Endocrinology and Infertility and is the Medical Director of the Reproductive Medicine Center at Froedtert Hospital. Her research interests include factors contributing to success with ART, the impact of BMI, and therapies for patients with diminished ovarian reserve.

View Fertility and Sterility at https://www.fertstert.org/