Take a sneak peekat this month's Fertility & Sterility! Articles discussed this month are:

Articles:

1. Beyond the numbers: antimüllerian hormone and astral follicle count are not independent predictors of embryo euploidy in in vitro fertilization with preimplantation genetic testing for aneuploidy
2. Stability and reliability of artificial intelligence models in embryo selection for in vitro fertilization
3. Perinatal complications of frozen vs. fresh embryo transfer among ongoing pregnancies: a cohort study conducted within the framework of a hypothetical trial
4. Similar outcomes, different timings: Luteal vs. follicular stimulation in IVF
5. Neonatal characteristics of children conceived with in vitro fertilization or intrauterine insemination compared with sibling births from unassisted conceptions
6. Governance of polygenic embryo screening: a qualitative study on the perspectives of clinicians and patients

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Welcome to Fertility & Sterility Roundtable! Each week, we will host a discussion with the authors of "Views and Reviews" and "Fertile Battle" articles published in a recent issue of Fertility & Sterility.

This week, we welcome Dr. Paula Amato and Professor Glenn Cohen to discuss the legal and ethical implications of in vitro gametogenesis (IVG) - the creation of human eggs and sperm in a laboratory setting using non-reproductive cells, such as skin or blood cells. Through our discussion, we will explore several issues raised by this nacent technology, including safety, Food and Drug Administration review, embryo destruction, eugenics, enhancement, unauthorized parenthood, inequitable access, and evolving conceptions of parenthood.

Dr. Paula Amato is Professor of Obstetrics & Gynecology and Director of the Division of Reproductive Endocrinology & Infertility at Oregon Health & Science University. She received her medical degree from the University of Toronto in Canada, where she also completed her Residency in Obstetrics & Gynecology, followed by a Fellowship in Reproductive Endocrinology & Infertility at the University of California, San Diego. Dr. Amato is past-president of the American Society for Reproductive Medicine. Her research focuses on innovative assisted reproductive technologies for the treatment of infertility and ovarian aging.

Professor Glenn Cohen is the James A. Attwood and Leslie Williams Professor of Law at Harvard Law School, where he directs the Center for Health Law Policy, Biotechnology, and Bioethics. A member of the National Academy of Medicine, his work focuses on the intersection of bioethics and the law. He has advised policymakers and global organizations on topics such as genetic privacy, medical AI, and reproductive rights, and his work has been featured by several prominent news outlets, including PBS, NPR, CNN, and The New York Times.

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In this month's Fertility & Sterility: Unplugged, we take a look at articles from F&S's sister journals! Topics this month include: x (2:41) a link between angiotension II and fibroid development (14:11), use of psychedelics in reproductive medicine (20:27) and an artificial intelligence tool for clinical decision making during stimulation (26:21). F&S Reviews: https://www.fertstertreviews.org/article/S2666-5719(25)00009-X/abstract F&S Science: https://www.fertstertscience.org/article/S2666-335X(25)00091-6/abstract Consider this: https://www.fertstert.org/news-do/psychedelic-medicine-revisited-advances-and-reproductive-health-implications F&S Reports: https://www.fertstertreports.org/article/S2666-3341(25)00017-0/fulltext

View the sister journals at:

• https://www.fertstertreviews.org
• https://www.fertstertreports.org
• https://www.fertstertscience.org

Take a sneak peak at this month's Fertility & Sterility! Articles discussed this month are:

Articles 01:51 Outcomes after frozen embryo transfer failure: changing the protocol does not improve live birth

14:23 Ovarian stimulation with follitropin delta is safe and effective: Results from the RITA randomized, double-blind, placebo-controlled trials

27:52 Donor Identity in Aotearoa New Zealand: a survey of parents regarding disclosure of donor conception to their donor-conceived children

36:55 The association of infertility, miscarriage, stillbirth, and parity with osteoporosis: a pooled analysis of five cohort studies

47:28 Extended Ovarian Transport for Centralized Tissue Cryobanking: Impact on Primordial Follicle Integrity

56:42 Temsirolimus and antimüllerian hormone protect fertility and the ovarian reserve against chemotherapy-induced damage in a murine model

01:04:09 Cost-Effectiveness of Single versus Double Embryo Transfer to Gestational Carriers for Male Same-Sex Intended Parents

View Fertility and Sterility Volume 125, Issue 1: https://www.fertstert.org/issue/S0015-0282(25)X0015-7

View Fertility and Sterility at https://www.fertstert.org/

In this month's Fertility & Sterility: Unplugged, we take a look at articles from F&S's sister journals! Topics this month include: (03:00) prevalence of endometrial hyperplasia and carcinoma among patients with PCOS; differences in trophectoderm gene expression among euploid blasts during extended in vitro culture (13:16), comparison of embryo transfer techniques and pregnancy outcomes (28:58), and exploring the association of ectopic pregnancy with embryonic competence (39:19).

F&S Reports: https://www.fertstertreports.org/article/S2666-3341(25)00101-1/fulltext F&S Science: https://www.fertstertscience.org/article/S2666-335X(25)00067-9/abstract F&S Reviews: https://www.fertstertreviews.org/article/S2666-5719(25)00002-7/fulltext Consider this: https://www.fertstert.org/news-do/beyond-tubal-factors-rethinking-ectopic-pregnancy-through-embryonic-competence-and

View the sister journals at:

• https://www.fertstertreviews.org
• https://www.fertstertreports.org
• https://www.fertstertscience.org

Fertility & Sterility on Air discusses ASRM INNOVATE, a reproductive health innovation summit that brings together dynamic healthcare professionals, thought leaders, and innovators to forge advancements in reproductive medicine through the synergy of science and technology. Join our host Kate Devine with Jared Robins, Anuja Dokras, and David Sable as they talk about formulating and executing the inaugural ASRM INNOVATE conference dedicated to identifying and addressing gaps and lack of innovation within the field of reproductive medicine by cultivating deliberate collaboration and exchange of ideas between healthcare professionals, innovators, and investors.

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Fertility & Sterility on Air is at the American Association of Gynecologic Laparoscopists 2025 Global Congress! In this episode, our host Pietro Bortoletto conducts a roundtable with expert reproductive surgeons Rebecca Flyckt, Zaraq Khan, and Michael Neblett on the surgical and medical management of adenomyosis with emphasis on diagnosis, innovative medical therapies, and uterus-sparing surgical techniques designed to optimize fertility outcomes.

View Fertility and Sterility at https://www.fertstert.org/

Take a sneak peek at this month's Fertility and Sterility! Articles discussed this month are:

Articles: 1. The reproductive journey of women with obesity undergoing assisted reproductive technology: an analysis of 48,595 in vitro fertilization cycles in 31,829 women

2. The reproductive endocrinology and infertility subspecialist: definition, training, and scope of practice in the United States

3. Clinical outcomes in patient-oriented strategies encompassing individualized oocyte number (POSEIDON) low-prognosis patients receiving in vitro fertilization / intracytoplasmic sperm injection treatment: a multi-center retrospective cohort study\

4. Gonadotropin-releasing hormone antagonist protocol is associated with higher oocyte yield in young women at high risk for low oocyte retrieval: a retrospective study using three statistical methods

5. Outcomes of in vitro fertilization cycles with embryo donation compared with double gamete donation with cryopreserved donor oocytes

6. Leveraging anti-Müllerian hormone and metaphase II oocyte yield to improve counseling for oocyte cryopreservation outcomes

7. Effect of a one-step fast warming protocol on reproductive outcomes of vitrified-warmed blastocysts

View the December 2025, Volume 124 Issue 6 of Fertility and Sterility at https://www.fertstert.org/issue/S0015-0282(25)X0013-3

View Fertility and Sterility at https://www.fertstert.org/

Welcome to Fertility & Sterility Roundtable! Each week, we will host a discussion with the authors of "Views and Reviews" and "Fertile Battle" articles published in a recent issue of Fertility & Sterility.

This week, we welcome Dr. Richard Paulson and Dr. Jamie Kuhlman to discuss Restorative Reproductive Medicine (RRM) — a field that describes itself as focusing on identifying and treating the root causes of infertility rather than bypassing or suppressing natural reproductive processes. In this episode, we explore whether RRM represents a truly novel approach to fertility care, examine its religious and political influences, and consider the potential risks the movement poses to access to evidence-based fertility treatments, including IVF.

Dr. Richard Paulson holds the Alia Tutor Chair in Reproductive Medicine and is Professor and vice-chair in the Department of Obstetrics and Gynecology at the University of Southern California, where he is also Director of the Fellowship in Reproductive Endocrinology and Infertility. He is past president of the American Society for Reproductive Medicine, and of the Pacific Coast Reproductive Society. Dr. Paulson has authored over 300 scientific articles and has received more than 35 awards for research and scientific presentations. He is the current Editor-in-Chief of "Fertility & Sterility Reports."

Dr. Kuhlman is a Licensed Psychologist and the Owner of Courageous Path Counseling, PLLC, in Nashville, TN. She specializes in infertility, postpartum, and maternal mental health through individual counseling and psychological evaluations for third-party reproduction. She is also a PRIMED Scholar with the American Society of Reproductive Medicine, focusing on advocacy within reproductive healthcare.

The unscientific nature of the arguments of "Restorative Reproductive Medicine" and why we need to understand them https://www.fertstertreports.org/article/S2666-3341(25)00111-4/fulltext

The illusion of reproductive choice: how restorative reproductive medicine violates reproductive autonomy and informed consent https://www.fertstert.org/article/S0015-0282(25)00596-5/fulltext

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Fertility & Sterility on Air is at the 2025 ASRM Scientific Congress & Expo in San Antonio, Texas (Part 3)! In this episode, our hosts Pietro Bortoletto, Blake Evans, Eve Feinberg, and Richard Paulson cover:

• Advancing ICSI robotics: follow up on the transition from remote to fully automated intracytoplasmic sperm injection with Gerardo Mendizabal (01:06)
• Overcoming challenges in ovarian visualization: a case report of a magnetic resonance imaging-guided oocyte retrieval resulting in live birth with Samir Babayev (11:02)
• Early pregnancy RhD-immune globulin practice patterns among REI physicians and the need for ASRM guidelines for RhIG administration with Nimerta Sandhu (20:30)
• At-home and mail-in semen analysis: a critical review of scientific validation, regulatory oversight, and marketing claims with Juan Varela (25:00)
• Preliminary analysis of a prospective cohort study of an epigenetic sperm quality test ("SpermQT") to predict success rates of ovarian stimulation treatment with Cassandra Roeca (31:05)
• A discussion with the 2025 Ira and Ester Rosenwaks New Investigator Award recipient, Min Yang (34:50)
• How combining medicine and coaching can empower patients through their fertility journey with Erica Bove (43:45)

View Fertility and Sterility at https://www.fertstert.org/