In today's episode Natalie shares the sad news that high amounts of sedentary behavior are associated with increased risks for several chronic conditions and mortality. However, she also asks and explores if our physical activity attenuates or even eliminates the detrimental effects of prolonged sitting? Research question: Does physical activity offset the detrimental association of (long) sitting time with mortality? Title of our meta-analysis: Physical activity attenuates the detrimental association of sitting time with mortality: A harmonised meta-analysis of data from more than one million men and women https://nih.brage.unit.no/nih-xmlui/bitstream/handle/11250/2440010/EkelundLancet2016.pdf?sequence=1 Reference: Ekelund, U., Steene-Johannessen, J., Brown, W. J., Fagerland, M. W., Owen, N., Powell, K. E., Bauman, A., Lee, I.-M., Lancet Physical Activity Series 2 Executive Committe, & Lancet Sedentary Behaviour Working Group. (2016). Does physical activity attenuate, or even eliminate, the detrimental association of sitting time with mortality? A harmonised meta-analysis of data from more than 1 million men and women. Lancet, 388(10051), 1302–1310. https://doi.org/10.1016/S0140-6736(16)30370-1