A young woman was killed in a senseless act of revenge. Could police identify the killer through a fingerprint on cloth?

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The huge amount of blood at the crime scene spoke of the violence of the attack; investigators describe it as "overkill," and it's usually an indication that the victim knew the attacker. Police hoped that, during the struggle, the killer had left some of his own blood - and his DNA - behind. Their challenge was to find it.

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When hunters reported finding a skull in a Texas canyon, police immediately began an investigation. At the scene, they found bits of clothing, a woman's shoe, some small bones and a strand of hair. An anthropologist determined the victim was a Caucasian woman, and that she'd been stabbed repeatedly. A forensic artist reconstructed her face, and the image was released to media. Eventually, police learned who she was. Now all they had to do was find her killer.

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After the rape and murder of a popular high school student, authorities ask the males in her social circles to volunteer DNA. When a match is found, the community is stunned.

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While staying at a hotel in St. Louis, Missouri, a Louisiana woman drowns in a bathtub. Her husband claims it was an accident, but detectives are skeptical as they discover evidence of foul play.

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The story of nurse Tanya Reid who may have murdered her own baby and was planning to murder her son.

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A retired police officer is discovered dead in his bed. Examination of the evidence at the crime scene, the tape from a bank surveillance camera, and forensic textbooks found in the victim's home are used to solve the murder.

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A fire erupted in the Kings Cross Underground Station in London, killing 31 people and injuring dozens more. Arson investigators were able to pinpoint the cause of the fire, but it would take state-of-the-art computer technology and experts in the field of fluid dynamics to explain why it became a deadly inferno.

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The victim had ingested a massive amount of cyanide. An unlikely clue - a flaw on a mailing envelope -- exposed a murderer who was willing to kill innocent people to get the one person he wanted.

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A series of murders near Sacramento, Calif., where prostitutes were gagged and molested, their clothes cut off in random patterns and their hair cut off.

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