I have had the privilege of working closely with Frank Wilczek for over 40 years, on and off, and we have written perhaps a dozen scientific papers together over that time. Our collaborations together were always a source of joy, and often of wonder, and I am pleased to say that a number of them had significant impact on our fields of study.

While I have had the privilege of working with many talented scientists during my career, Frank is unique. He is one of the most broadly read, deep, and creative scientists I have known. To first approximation, he has read everything in science, and one of the characteristics of our own collaborations that has been so much fun is entering an entirely new field of study and learning how much is known about it, and how that knowledge might be used in new contexts.

Frank is likely the most significant theoretical physicist of my generation, and along with Ed Witten, perhaps the intellectually most gifted. That he won the Nobel Prize for work performed as a graduate student with David Gross to develop the theory of one of the four known forces in nature is notable, but it just scratches the surface of his interests and accomplishments.

While Frank and I have appeared onstage together on numerous occasions, I was waiting for the opportunity to sit down with him for an extended period to discuss his life in science, and the areas of study that reflect the most significant developments of recent times, and the outstanding challenges in our field. It was a pleasure to be able to do so for this podcast. I hope you enjoy it as much as I did, and that it inspires your interest in the world around us.

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