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Physicist and computer scientist Stephen Wolfram explores how simple rules can generate complex realities, offering a bold new vision of fundamental physics and the structure of the universe. Additionally, from the foundations of cellular automata to the discovery of surprising patterns in nature, Wolfram shows how computation reshapes our understanding of reality and revolutionizes the way we think about science. 

Stephen Wolfram is a British-American computer scientist, physicist, and businessman. He is known for his work in computer algebra and theoretical physics. In 2012, he was named a fellow of the American Mathematical Society. He is the founder and CEO of the software company Wolfram Research, where he works as chief designer of Mathematica and the Wolfram Alpha answer engine.

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Humanity’s future is now framed by artificial intelligence (AI) and increasing interventions in the body to enhance features and functions. This is transhumanism. Considering the stakes, and the dangers, a philosophical perspective is imperative.

Featuring interviews with Paul Griffiths, Nathan Lents, Carol Cleland, Quayshawn Spencer, Rachell Powell, S. Joshua Swamidass, Terrence Deacon, and Massimo Pigliucci.

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Many people believe that out-of-the-body experiences (OBEs) and near-death experiences (NDEs) are real. We do not assess the evidence and arguments, pro or con. We do explore what OBEs and NDEs would mean, if real, for theories of consciousness.

This episode features interviews with Bernardo Kastrup, Etzel Cardeña, Àlex Gómez-Marín, and Liad Mudrik.

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Two kinds of questions probe evolution vs. religion. The first explores discrepancies, even contradictions, between the science of evolution and the beliefs of religion. The second examines how religion itself evolved.

Featuring interviews with Richard Dawkins, Michael Ruse, Alexander Rosenberg, Helen De Cruz, Massimo Pigliucci, and Elliott Sober.

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Clement Vidal, philosopher of science and astrobiologist, discusses the idea of something rather than nothing, differing religious worldviews, fine tuning and metaphysics, and more.

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Dr. Clément Vidal is a philosopher with a background in logic and cognitive sciences. He is co-director of the 'Evo Devo Universe' community and founder of the 'High Energy Astrobiology' prize. To satisfy his intellectual curiosity when facing the big questions, he brings together many areas of knowledge such as cosmology, physics, astrobiology, complexity science, evolutionary theory and philosophy of science.

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What can evolution reveal about the developmental history of thinking and feeling? How did cognition and emotion (affect) co-develop over evolutionary time? Can evolution help solve the mystery of consciousness?

Featuring interviews with Peter Godfrey-Smith, S. Joshua Swamidass, Rachell Powell, Denis Noble, Terrence Deacon, Paul E. Griffiths, Helen De Cruz, and John Dupré.

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Dr. Mark Bailey writes about the intersection between artificial intelligence, complexity, and national security. He is an associate professor at the National Intelligence University, where he is the Department Chair for Cyber Intelligence and Data Science, as well as the Director of the Data Science Intelligence Center.

This Chat was made possible by MindFest 2025: "Sentience, Autonomy, and the Future of Human-AI Interaction", a two-day event presented by the Center for the Future Mind.

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