For those using drugs in Vancouver’s Downtown Eastside, Thomus Donaghy was a lifeline, committed to saving those on the brink of overdose.

On the night of July 27, 2020, Donaghy, a volunteer at the Overdose Prevention Society, had just saved another life. Moments later, he lost his own.

Today, the stories of two men whose lives were shaped by a city in the grips of an overdose epidemic, the tragic circumstances that brought them together that night, and why Maximus Roland Hayes, the man who killed Donaghy, wants to make sure his life wasn't lost for nothing.

Our guests are CBC Vancouver reporter Jason Proctor, and Sara Blyth, the executive director of Vancouver’s Overdose Prevention Society.

Omicron is spreading rapidly in Canada. Barely two weeks after the first cases of the coronavirus variant were identified in Ontario, it became the dominant strain in the province, and experts say that will soon be the case across the country. Even as Canada is reporting some of the highest daily case counts seen throughout the whole pandemic, some doctors say the real numbers could be several times higher because of the difficulties many people face in accessing tests.

Today, Dr. Zain Chagla, an infectious diseases physician at St. Joseph’s Healthcare in Hamilton, explains the latest research on Omicron from around the world — and how that research can help inform your choices around holiday gatherings.

The Matrix was a blockbuster hit when it came out in 1999. Now, more than 20 years later, the film still feels relevant — whether it’s people talking about “taking the red pill” or theorizing that we’re all really living in a computer simulation — the movie starring Keanu Reeves as Neo and Laurence Fishburne as Morpheus permeated the culture.

With the Matrix Resurrections opening in Canada on Wednesday, Jayme Poisson speaks with John Semley about why the film made such an impact then, and how its influence is still felt today. Plus, Charley Archer explains why the original movie, made by two trans women Lilly and Lana Wachowski, is an iconic piece of trans art.

Longtime Jeffrey Epstein companion Ghislaine Maxwell is on trial in New York City this month, facing decades in prison over allegations of sex trafficking and conspiracy, all related to her relationship with the convicted sex offender and financier. Maxwell maintains that she is innocent.

Victoria Bekiempis is reporting on the trial for the Guardian. As the trial approaches its conclusion, she explains the prosecution’s case, the accuser’s testimony, and how the defence pushed back.

Extracting bitumen from Alberta’s oilsands requires water — lots of it. And for decades, oilsands companies in Canada were banned from releasing the used water back into the environment. So as the industry skyrocketed, the reservoirs of water grew.

There are now more than 1.4 trillion litres of toxic wastewater stored in these tailings ponds. Experts say that could be a disaster waiting to happen.

The federal government is working on regulations that would eventually allow companies to treat and release the water back into rivers and lakes. Business reporter Kyle Bakx explains why some are questioning the safety of that plan — while others say it’s absolutely necessary.

With the holidays approaching and the Omicron variant spreading rapidly in Canada, people are reconsidering their response.

In a busy week of Omicron warnings, Chief Public Health Officer Dr. Theresa Tam said cases are expected to “rapidly escalate”; in her fiscal and economic update, Finance Minister Chrystia Freeland committed a $4.5 billion “variant response” contingency; and Canada advised against all non-essential international travel. Provinces are expanding testing and booster access.

Today on Front Burner, a discussion with Globe and Mail health columnist André Picard about our pandemic cycle of delay and panic, and the lessons and tools that still might make us better prepared for Omicron.

HBO’s Succession came out of the gate quietly back in 2018. And even as critics raved over its stylish production, intricate plotting and viciously sharp humour, it took a while to catch on. Now, it’s easily one of the most influential and discussed TV shows in a long time.

Structured like a chamber drama set in the corridors of elite power and influence, it revolves around the highly successful but highly dysfunctional Roy clan and their sprawling right wing media empire. The central conflict is between the brilliant and ruthless patriarch Logan Roy and his ambitious but flawed children, each vying for his love and attention while at the same time plotting to dethrone him.

This week, its third season came to a dramatic end so today on Front Burner we talk to writer and showrunner of CBC’s Pop Chat podcast, Amil Niazi and Vulture’s Jackson McHenry on what makes Succession so compelling, and how it’s become a cultural institution. Warning: this episode contains major spoilers.

The debate over Quebec’s controversial secularism law, known as Bill 21, has been reignited after a teacher was told she can no longer teach her Grade 3 class, because she wears a hijab.

Fatemeh Anvari was hired this fall at Chelsea Elementary School, during a period of confusion over whether English school boards had to enforce the religious symbols ban. Now, in the wake of a recent court decision on the ban, Anvari has been forced out of classroom teaching.

Today, we’re speaking to Montreal teacher Maha Kassef about the far-reaching consequences of Bill 21 for both teachers and students. Then, CBC reporter Jonathan Montpetit gives us the latest on the court and political battles surrounding the law — and how they call into question our understanding of how much Canada’s constitution really protects individual rights and freedoms.

For a year, a 49-year-old woman in B.C. posed as a nurse at a Vancouver hospital, even assisting in gynecological surgeries, despite not actually being a nurse. Brigitte Cleroux has since been criminally charged, but it turns out she has a long history of impersonations dating back decades and spanning multiple provinces.

Now, former patients are left with serious questions about the care they received, and how she was able to even get the job in the first place.

Today, CBC Vancouver’s Bethany Lindsay tells us more about those patients, and CBC Ottawa’s Shaamani Yogaretnam explains Cleroux’s decades of impersonations.

On Monday, as the Recording Academy began its final round of voting for the 2022 Grammy winners, people learned Drake was off the ballot.

Drake and his management had asked the Academy to pull his two nominations.

He still hasn’t offered an explanation, but this is the latest in a series of tensions between Drake and the Grammys: he’s questioned their relevance in his lyrics, defended The Weeknd after a snub and even criticized the Academy while accepting a trophy.

Today on Front Burner, music journalist and host of Marvin’s Room A. Harmony joins us to explain why so many Hip Hop artists are expressing frustration with the Grammys, and whether a show with limited recognition of Black talent can remain relevant.