Frontiers

Frontiers

By BBC Radio 4Science
Download on the App Store

Frontiers episodes

  • Plate Tectonics and Life

    Earthquakes are feared for their destructive, deadly force. But they are part of a geological process, plate tectonics, that some scientists say is vital for existence of life itself. Without the ever-changing land surfaces that plate tectonics produces , or the high continental masses raised above sea level by earthquake activity, planet Earth would atrophy into a lifeless mass like our neighbour Mars. But why is Earth the only planet with plate tectonics? And when did they start. The clues are so faint, the traces so ephemeral, that researchers are only now beginning to find tentative answers. And extraordinarily, some say that life itself has changed the forces in plate tectonics, and helped to shape the world.

    29 min
  • Whatever happened to biofuels?

    Whatever happened to biofuels? They were seen as the replacement for fossil fuels until it was realised they were being grown on land that should have been used for food crops. But now there is serious research into new ways of producing biofuels, from waste materials, from algae and from bacteria.

    Gaia Vince takes to the water of Strangford Lough in Northern Ireland where Professor Matthew Dring and Dr Karen Mooney from Queens University, Belfast, are experimenting in growing algae that could be turned into fuel. She visits Professor Alison Smith's algae lab at Cambridge University. Graham Ellis from Solazyme in California explains how his company has already made fuel from algae that has been sold at the pumps and powered a plane, in a mixture with conventional fuel. And Professor Nick Turner at Manchester University and Professor John Love at Exeter University talk about how they are manipulating bacteria to make diesel.

    29 min
  • 19/06/2013

    England's chief medical officer recently warned that within twenty years, the spread of antibiotic resistance may have returned us to an almost 19th century state of medicine. Infections following routine operations will be untreatable and fatal because so many common bacteria will have acquired immunity to all the available antibiotic drugs.

    The vast majority of the antibiotics we rely upon today were developed between the 1940s and 1970s. There has been no new class of antibiotic for 25 years.

    A radically different approach to dealing with bacteria would be stop them from communicating and coordinating their attacks, rather than trying to kill them. The bugs would be rendered harmless and much less likely to develop drug resistance.

    This is the hope of researchers who are working on an aspect of bacterial life known as Quorum Sensing.

    Bacteria may just be single-celled organisms but microbiologists now realise they have a kind of social life. They need to cooperate and coordinate their attacks on the bodies they infect.

    Many kinds of bacteria only become dangerous to us when they sense that their numbers are high enough. Only when they 'know' that there are enough of them to overwhelm human defences, do they release their toxins and cause illness and death.

    They monitor the number of their fellow bugs by sensing the concentration of a message molecule which they all manufacture and secrete into the environment. It's a rudimentary form of communication which many bacteria use to synchronise their activities.

    In Frontiers, Geoff Watts talks to scientist and doctors who are exploring this phenomenon in disease-causing bacteria, and trying to devise ways of interfering with the microbial communications. One line of thinking is the development of drugs which stop the microbes from either 'talking' or 'hearing' the chemical messages.

    Another more radical idea is to treat infected patients with doses of the kind of bacteria causing the illness - except that the 'medicinal' bugs would be ones that would subvert the communication system and bring the infection to an end. At least, that is the theory.

    29 min
  • Build Me a Brain

    When President Obama recently complained, that although "we can identify

    galaxies light years away, study particles smaller than an atom ... we
    still haven't unlocked the mystery of the three pounds of matter that
    sits between our ears" - he called on scientists to unravel the
    trillions of neural connections inside our brains that make our minds work.

    Some researchers are already doing that - trying to understand the brain

    by starting to build one. At Reading University, at the newly
    constructed Brain Embodiment Laboratory, researchers plan to connect
    cultures of living human neurons to robots to give meaning to their
    neural activity. At Georgia Tech, Atlanta, neuroengineer Steve Potter
    agrees that cultured neurons not connected to the outside world suffer
    sensory deprivation. His neural arrays descend into spasms of epileptic
    activity when left alone. When plugged in, they can control machines
    across the planet.

    "I believe these cultures are half-way to having a mind," says Potter.

    "Wired up to listen to their own outputs, they could be self aware."

    Other researchers are building brains from inanimate materials - using

    tendrils of silver, silicon and sulphur that spring into life like
    activity when wired up to electricity. At Stanford University, plans are
    afoot to meld them with living neurons - perhaps to enhance our thought
    processes.

    These devices can learn, remember and process information - but do they

    think? Can these scientists really build a brain? And what would it tell
    us about ours if they could?

    29 min
  • Forensic Phonetics

    Many crimes are planned, executed and sometimes gloated over using mobile phones. And the move to digital means that recordings are cheap and easy to make for the criminals themselves, as well as for their victims and witnesses.

    Ranging from death threats left on voicemails and hoax 999 calls to fraudulent calls to banks and conversations between terrorists, phoneticians analyse the minute acoustic components of the human voice to determine not only what was said but to create a profile of the culprit, or work out if a suspect's voice matches the voice in the criminal recording.

    While it's not possible to identify a unique 'voiceprint', as it is with fingerprints and DNA, speech scientists are developing new ways of teasing out the distinctive characteristics in human speech to improve their ability to identify a particular speaker.

    Forensic audio specialists can now determine with surprising accuracy whether a digital recording has been tampered with, and when exactly it was made. The gentle 'hum', that is constantly emitted from electrical power sources, is embedded in digital recordings. So by extracting this 'hum', which is emitted in a random pattern, forensic scientists can now pinpoint the date and time of the recording.

    Rebecca Morelle looks at some of the new research in this growing area of forensics, including the credibility of ear witness accounts and whether it's possible to distinguish hoax 999 calls from genuine ones.

    This branch of forensics has played a crucial role in a number of high profile cases, including the conviction of John Humble as the hoax caller claiming to be the Yorkshire Ripper, and identifying the mystery cougher who tried to defraud the gameshow 'Who Wants to Be a Millionaire'.

    Producer: Beth Eastwood.

    28 min
  • 05/12/2012

    A decade ago, the Human Genome Project revealed that only 1% of our DNA codes for the proteins that make our bodies. The rest of the genome, it was said, was junk, in other words with no function. But in September another massive international project, called ENCODE, announced that the junk DNA is useful after all. Adam Rutherford reports on the significance of this major discovery.

    He visits the Wellcome Trust Sanger Institute outside Cambridge where the vast amount of data about our genome is produced and analysed. And he finds out how this new information is beginning to give insights into the origin and treatment of diseases, such as cancer.

    Adam also discovers that the study of genomes has changed dramatically since he finished his PhD: it's now all done in machines and not at the lab bench.

    29 min
  • Brain Machine Interfaces

    Can reading the mind allow us to use thought control to move artificial limbs?

    Neuroscientist Miguel Nicolelis, is one of the world's leading researchers into using the mind to control machines. One of his aims is to build a suit that a quadriplegic person can wear and control so that he or she can kick a football at the opening of the 2014 World Cup in Brazil. His lab is working on ways of providing a sense of touch to these limbs so that the prosthetics feel more like a part of a person's body and less like an artificial appendage.

    Geoff Watts visits Nicolelis' laboratory to see just how near we are to achieving his aim on the football pitch.

    29 min
  • Anthropocene

    Humanity's impact on the Earth is so profound that we're creating a new geological time period. Geologists have named the age we're making the Anthropocene. The changes we're making to the atmosphere, oceans, landscape and living things will leap out of the rocks forming today to Earth scientists of the far future, as clearly as the giant meteorite that ended the Age of the Dinosaurs does to today's researchers.

    Science writer Gaia Vince looks at the impact of these planetary transformations from the perspective of geological time. When was the last time comparable events happened in Earth history, and are what are the key marks we're making on the planet that define the Anthropocene?

    Gaia explores the distinctive fossil record we will leave behind on the planet. Leading biologists and palaeontologists say this that will mark out the Anthropocene as a distinctive chapter in Earth history - on a par with the evidence of the mass extinction which took out the dinosaurs and launched a geological era 65 million years ago. "This time, we are the asteroid," says Berkeley's Antony Barnosky. Extinction rates around the world are approaching those estimated for times in the deep past when most species became extinct.

    Far future fossil hunters may also discover a weirdly large number of large-sized fossil mammal species bones in the rocks of our times. Even more unnaturally, they come from just a tiny handful of species and they will be in the strata across every continent- a geological representation of billions of domestic livestock and the billions of people they fed.

    Some of our cities may also be preserved as 'artificial' layers of rock in the geological record. They will be like no other strata before in the history of the Earth. But what would a fossilised metropolis - with its concrete and glass buildings and underground train tunnels and sewers - look like in ten million years?

    29 min
  • Why do women live longer than men?

    In the UK today, male life expectancy is 78 years old, whereas women will on average live four years longer.

    Evolutionary biologist Dr Yan Wong looks at the latest evidence suggesting that where ageing is concerned, men seem to be at a genetic disadvantage. From research on ancient Korean eunuchs to laboratory fruit flies, new studies seek the answer to why males across the animal kingdom live faster and die younger.

    So, is the gender gap here to stay?

    29 min
  • Future of Particle Physics

    Finding the Higgs boson on July 4th was the last piece in physicists' Standard model of matter. But Tracey Logan discovers there's much more for them to find out at the Large Hadron Collider. To start with there is a lot of work to establish what kind of Higgs boson it is.

    Tracey visits CERN and an experiment called LHCb which is trying to find out why there's a lot more matter than anti-matter in the universe today. Dr Tara Shears of Liverpool University is her guide.

    Tracey also talks to physicists who are hoping to find dark matter in the debris of the collisions at the LHC. Scientists know there's plenty of dark matter in the universe, from its effects on galaxies, but they don't know what it is. Tracey discovers that this fact isn't stopping the particle physicists carrying out experiments.

    29 min

About Frontiers

From the publisher's feed

Programme exploring new ideas in science and meeting the scientists and researchers responsible for them, as well as hearing from their critics

More shows like Frontiers

Global News Podcast by BBC World Service

Global News Podcast

7,608 Listeners

Newshour by BBC World Service

Newshour

1,047 Listeners

In Our Time by BBC Radio 4

In Our Time

5,478 Listeners

The Documentary Podcast by BBC World Service

The Documentary Podcast

1,794 Listeners

6 Minute English by BBC Radio

6 Minute English

1,819 Listeners

Learning English Conversations by BBC Radio

Learning English Conversations

1,034 Listeners

The Infinite Monkey Cage by BBC Radio 4

The Infinite Monkey Cage

1,906 Listeners

Curious Cases by BBC Radio 4

Curious Cases

770 Listeners

You're Dead to Me by BBC Radio 4

You're Dead to Me

3,220 Listeners

Americast by BBC News

Americast

715 Listeners