
Sign up to save your podcasts
Or


Blaise Agüera y Arcas explores some mind-bending ideas about what intelligence and life really are—and why they might be more similar than we think (filmed at ALIFE conference, 2025 - https://2025.alife.org/).
Life and intelligence are both fundamentally computational (he says). From the very beginning, living things have been running programs. Your DNA? It's literally a computer program, and the ribosomes in your cells are tiny universal computers building you according to those instructions.
**SPONSOR MESSAGES**
—
Prolific - Quality data. From real people. For faster breakthroughs.
https://www.prolific.com/?utm_source=mlst
—
cyber•Fund https://cyber.fund/?utm_source=mlst is a founder-led investment firm accelerating the cybernetic economy
Oct SF conference - https://dagihouse.com/?utm_source=mlst - Joscha Bach keynoting(!) + OAI, Anthropic, NVDA,++
Hiring a SF VC Principal: https://talent.cyber.fund/companies/cyber-fund-2/jobs/57674170-ai-investment-principal#content?utm_source=mlst
Submit investment deck: https://cyber.fund/contact?utm_source=mlst
—
Blaise argues that there is more to evolution than random mutations (like most people think). The secret to increasing complexity is *merging* i.e. when different organisms or systems come together and combine their histories and capabilities.
Blaise describes his "BFF" experiment where random computer code spontaneously evolved into self-replicating programs, showing how purpose and complexity can emerge from pure randomness through computational processes.
https://en.wikipedia.org/wiki/Blaise_Ag%C3%BCera_y_Arcas
https://x.com/blaiseaguera?lang=en
TRANSCRIPT:
https://app.rescript.info/public/share/VX7Gktfr3_wIn4Bj7cl9StPBO1MN4R5lcJ11NE99hLg
TOC:
00:00:00 Introduction - New book "What is Intelligence?"
00:01:45 Life as computation - Von Neumann's insights
00:12:00 BFF experiment - How purpose emerges
00:26:00 Symbiogenesis and evolutionary complexity
00:40:00 Functionalism and consciousness
00:49:45 AI as part of collective human intelligence
00:57:00 Comparing AI and human cognition
REFS:
What is intelligence [Blaise Agüera y Arcas]
https://whatisintelligence.antikythera.org/ [Read free online, interactive rich media]
https://mitpress.mit.edu/9780262049955/what-is-intelligence/ [MIT Press]
Large Language Models and Emergence: A Complex Systems Perspective
https://arxiv.org/abs/2506.11135
Our first Noam Chomsky MLST interview
https://www.youtube.com/watch?v=axuGfh4UR9Q
Chance and Necessity [Jacques Monod]
https://monoskop.org/images/9/99/Monod_Jacques_Chance_and_Necessity.pdf
Wonderful Life: The Burgess Shale and the History of Nature [Stephen Jay Gould]
https://www.amazon.co.uk/Wonderful-Life-Burgess-Nature-History/dp/0099273454
The major evolutionary transitions [E Szathmáry, J M Smith]
https://wiki.santafe.edu/images/0/0e/Szathmary.MaynardSmith_1995_Nature.pdf
Don't Sleep, There Are Snakes: Life and Language in the Amazonian Jungle [Dan Everett]
https://www.amazon.com/Dont-Sleep-There-Are-Snakes/dp/0307386120
The Nature of Technology: What It Is and How It Evolves [W. Brian Arthur]
https://www.amazon.com/Nature-Technology-What-How-Evolves-ebook/dp/B002RI9W16/
The MANIAC [Benjamin Labatut]
https://www.amazon.com/MANIAC-Benjam%C3%ADn-Labatut/dp/1782279814
When We Cease to Understand the World [Benjamin Labatut]
https://www.amazon.com/When-We-Cease-Understand-World/dp/1681375664/
The Boys in the Boat [Dan Brown]
https://www.amazon.com/Boys-Boat-Americans-Berlin-Olympics/dp/0143125478
[Petter Johansson] (Split brain)
https://www.lucs.lu.se/fileadmin/user_upload/lucs/2011/01/Johansson-et-al.-2006-How-Something-Can-Be-Said-About-Telling-More-Than-We-Can-Know.pdf
If Anyone Builds It, Everyone Dies [Eliezer Yudkowsky, Nate Soares]
https://www.amazon.com/Anyone-Builds-Everyone-Dies-Superhuman/dp/0316595640
The science of cycology
https://link.springer.com/content/pdf/10.3758/bf03195929.pdf
By Machine Learning Street Talk (MLST)4.7
8585 ratings
Blaise Agüera y Arcas explores some mind-bending ideas about what intelligence and life really are—and why they might be more similar than we think (filmed at ALIFE conference, 2025 - https://2025.alife.org/).
Life and intelligence are both fundamentally computational (he says). From the very beginning, living things have been running programs. Your DNA? It's literally a computer program, and the ribosomes in your cells are tiny universal computers building you according to those instructions.
**SPONSOR MESSAGES**
—
Prolific - Quality data. From real people. For faster breakthroughs.
https://www.prolific.com/?utm_source=mlst
—
cyber•Fund https://cyber.fund/?utm_source=mlst is a founder-led investment firm accelerating the cybernetic economy
Oct SF conference - https://dagihouse.com/?utm_source=mlst - Joscha Bach keynoting(!) + OAI, Anthropic, NVDA,++
Hiring a SF VC Principal: https://talent.cyber.fund/companies/cyber-fund-2/jobs/57674170-ai-investment-principal#content?utm_source=mlst
Submit investment deck: https://cyber.fund/contact?utm_source=mlst
—
Blaise argues that there is more to evolution than random mutations (like most people think). The secret to increasing complexity is *merging* i.e. when different organisms or systems come together and combine their histories and capabilities.
Blaise describes his "BFF" experiment where random computer code spontaneously evolved into self-replicating programs, showing how purpose and complexity can emerge from pure randomness through computational processes.
https://en.wikipedia.org/wiki/Blaise_Ag%C3%BCera_y_Arcas
https://x.com/blaiseaguera?lang=en
TRANSCRIPT:
https://app.rescript.info/public/share/VX7Gktfr3_wIn4Bj7cl9StPBO1MN4R5lcJ11NE99hLg
TOC:
00:00:00 Introduction - New book "What is Intelligence?"
00:01:45 Life as computation - Von Neumann's insights
00:12:00 BFF experiment - How purpose emerges
00:26:00 Symbiogenesis and evolutionary complexity
00:40:00 Functionalism and consciousness
00:49:45 AI as part of collective human intelligence
00:57:00 Comparing AI and human cognition
REFS:
What is intelligence [Blaise Agüera y Arcas]
https://whatisintelligence.antikythera.org/ [Read free online, interactive rich media]
https://mitpress.mit.edu/9780262049955/what-is-intelligence/ [MIT Press]
Large Language Models and Emergence: A Complex Systems Perspective
https://arxiv.org/abs/2506.11135
Our first Noam Chomsky MLST interview
https://www.youtube.com/watch?v=axuGfh4UR9Q
Chance and Necessity [Jacques Monod]
https://monoskop.org/images/9/99/Monod_Jacques_Chance_and_Necessity.pdf
Wonderful Life: The Burgess Shale and the History of Nature [Stephen Jay Gould]
https://www.amazon.co.uk/Wonderful-Life-Burgess-Nature-History/dp/0099273454
The major evolutionary transitions [E Szathmáry, J M Smith]
https://wiki.santafe.edu/images/0/0e/Szathmary.MaynardSmith_1995_Nature.pdf
Don't Sleep, There Are Snakes: Life and Language in the Amazonian Jungle [Dan Everett]
https://www.amazon.com/Dont-Sleep-There-Are-Snakes/dp/0307386120
The Nature of Technology: What It Is and How It Evolves [W. Brian Arthur]
https://www.amazon.com/Nature-Technology-What-How-Evolves-ebook/dp/B002RI9W16/
The MANIAC [Benjamin Labatut]
https://www.amazon.com/MANIAC-Benjam%C3%ADn-Labatut/dp/1782279814
When We Cease to Understand the World [Benjamin Labatut]
https://www.amazon.com/When-We-Cease-Understand-World/dp/1681375664/
The Boys in the Boat [Dan Brown]
https://www.amazon.com/Boys-Boat-Americans-Berlin-Olympics/dp/0143125478
[Petter Johansson] (Split brain)
https://www.lucs.lu.se/fileadmin/user_upload/lucs/2011/01/Johansson-et-al.-2006-How-Something-Can-Be-Said-About-Telling-More-Than-We-Can-Know.pdf
If Anyone Builds It, Everyone Dies [Eliezer Yudkowsky, Nate Soares]
https://www.amazon.com/Anyone-Builds-Everyone-Dies-Superhuman/dp/0316595640
The science of cycology
https://link.springer.com/content/pdf/10.3758/bf03195929.pdf

475 Listeners

434 Listeners

303 Listeners

211 Listeners

196 Listeners

304 Listeners

501 Listeners

129 Listeners

49 Listeners

94 Listeners

208 Listeners

561 Listeners

33 Listeners

22 Listeners

40 Listeners