LessWrong (30+ Karma)

“Guess I Was Wrong About AIxBio Risks” by J Bostock


Listen Later

I was slightly worried about sociohazards of posting this here, but the cat's already out of the bag on this one: the authors of the paper put it up on BioRXiv and got an article written about them in Nature, as well as getting into a bunch of newspapers and all over twitter. I expect that the marginal audience of LessWrong is much more heavily enriched in people who'll use this information to do good than to do evil.

TL;DR:
If anyone reading this works in Biosecurity: nucleotide synthesis companies should start using protein structure annotation as part of their screening protocol for genes, if they aren't already.

Intro

The Fermi Paradox is the question of why we don't see any evidence of aliens spreading out across the galaxy, despite there being loads of planets on which intelligent life could evolve.

The Germy Paradox is the question of [...]




---

Outline:

(00:48) Intro

(01:23) I

(04:34) II

(06:52) III

The original text contained 4 footnotes which were omitted from this narration.

---

First published:

September 29th, 2025

Source:

https://www.lesswrong.com/posts/k5JEA4yFyDzgffqaL/guess-i-was-wrong-about-aixbio-risks

---

Narrated by TYPE III AUDIO.

---

Images from the article:

Apple Podcasts and Spotify do not show images in the episode description. Try Pocket Casts, or another podcast app.

...more
View all episodesView all episodes
Download on the App Store

LessWrong (30+ Karma)By LessWrong


More shows like LessWrong (30+ Karma)

View all
The Daily by The New York Times

The Daily

112,214 Listeners

Astral Codex Ten Podcast by Jeremiah

Astral Codex Ten Podcast

131 Listeners

Interesting Times with Ross Douthat by New York Times Opinion

Interesting Times with Ross Douthat

7,239 Listeners

Dwarkesh Podcast by Dwarkesh Patel

Dwarkesh Podcast

559 Listeners

The Ezra Klein Show by New York Times Opinion

The Ezra Klein Show

16,276 Listeners

AI Article Readings by Readings of great articles in AI voices

AI Article Readings

4 Listeners

Doom Debates! by Liron Shapira

Doom Debates!

14 Listeners

LessWrong posts by zvi by zvi

LessWrong posts by zvi

2 Listeners