Dr. Tom O'Bryan is an internationally recognized and sought-after speaker specializing in wheat, its impact on health, and the development of autoimmune diseases as they occur inside and outside the gut. Dr. Tom is the author of You Can Fix Your Brain and The Autoimmune Fix, the creator of the documentary series "Betrayal: The Autoimmune Solution They're Not Telling You" and he holds teaching positions with the Institute of Functional Medicine and the National University of Health Sciences.

Together we discuss the dangers of going gluten-free, the history behind autoimmune disease, the power of employing different antibodies, molecular mimicry in the gut, and more. Dr. Tom shares his knowledge and passion about gluten and autoimmune conditions and doesn't shy away from the facts about what it will take to heal an adult's relationship with gluten.

I'm your host, Evelyne Lambrecht, thank you for designing a well world with us.

Key Takeaways:

[2:05] Dr. Tom's interest in gluten and autoimmune conditions initially developed from infertility issues.

[5:55] Distinguishing gluten sensitivity from wheat sensitivity and celiac disease from non-celiac disease.

[9:48] The four horsemen of Celiac research, their findings, and the tests that are being conducted on gluten sensitivity.

[12:30] Labs that test IGG and IGA and the surprising lack of accurate results.

[17:03] The value of lab testing sequences and specific genetic testing.

[21:12] Details of the most commonly tested protein in wheat and their actions.

[28:25] The key cause of intestinal permeability and leaky gut in every single human.

[30:52] The negative impact of glyphosate on our food supply.

[33:55] Dr. Tom's son is a living example of a healthy microbiome.

[34:42] The revealing relationship between memory B-cells and gluten.

[39:09] Humans have been negatively reacting to wheat through transient permeability for over a century.

[43:05] Five elements of the perfect storm that activate wheat-related disorders including genetics and environmental triggers.

[48:22] Details regarding elevated zonulin and the transient leaky gut.

[49:35] Autoimmune antibodies and their relationship with the thyroid.

[52:52] Dr. Tom's approach to teaching patients to implement effective gluten-free diets.

[58:46] Rebuilding the microbiome and employing the digestive enzymes that actually work.

[59:33] Dr. Tom's favorite personal supplements and health practices and the key knowledge he has gained over the course of his career.

Episode Resources:

Tom O'Bryan

House Plants Are Air Purifiers

The Dangers of a Gluten-free Diet

Nutritional Wheat Amylase-Trypsin Inhibitors Promote Intestinal Inflammation via Activation of Myeloid Cells

All disease begins in the (leaky) gut: role of zonulin-mediated gut permeability in the pathogenesis of some chronic inflammatory diseases

Design for Health Resources:

Designs for Health

Blog: Serum-derived Bovine Immunoglobulins and Gut Barrier Function

Blog: Polyphenols May Support the Body's Response to Increased Intestinal Permeability

Blog: The Relationship Between Histamine Intolerance and Gastrointestinal Health

Blog: How Diet Guards Against Leaky Gut

Blog: Supportive Role Probiotics Play on Gut-Brain Axis and Mood Health, According to Recent Review

Blog: The Adaptogen Advantage

Visit the Designs for Health Research and Education Library which houses medical journals, protocols, webinars, and our blog.