The mpox case surge in Africa has been declared a Public Health Emergency of International Concern (PHEIC) by the WHO. A new clade of the virus has emerged since the 2022 outbreak which has led to a rapid increase in cases. Professor Salim Abdool Karim, who is the the chair of the Africa CDC’s Emergency Consultative Group and the director of CAPRISA, the Center for the AIDS Programme of Research in South Africa, joins Gavin Cleaver and Maneet Virdi to lay out in clear terms what's happening in Africa, what the PHEIC means, and what the future could look like.

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