Could repeated liver stiffness measurement offer a practical approach to population-based liver fibrosis screening? In this episode, we speak with Pere Ginès about the LiverScreen study, which analysed changes in liver stiffness over time across three European cohorts and identified the risk factors associated with these changes.

Click here to read the full article:

https://www.thelancet.com/journals/langas/article/PIIS2468-1253(26)00091-9/fulltext

The Lancet Gastroenterology & Hepatology in conversation with...  is part of the Lancet Group podcast offering. 

Editorial team: editor-in-chief Rob Brierley, deputy editor Aisling O'Brien, and senior editor Bethany Gomersall

Podcast editing: Matteo Simonetti

Visit https://www.thelancet.com/multimedia to learn more about our multimedia offering. 

Find the best science for better lives at https://www.thelancet.com/

In children with Crohn’s disease who achieve remission through exclusive enteral nutrition, what's the optimal dietary therapy to maintain remission without the use of medication or surgery? Frank Ruemmele (Université Paris Cité) talks through the CD-Hope randomised controlled trial and its implications for clinical practice.

Click here to read the full article:

https://www.thelancet.com/journals/langas/article/PIIS2468-1253(25)00262-6/fulltext

The Lancet Gastroenterology & Hepatology in conversation with...  is part of the Lancet Group podcast offering. 

Editorial team: editor-in-chief Rob Brierley, deputy editor Aisling O'Brien, and senior editor Bethany Gomersall

Podcast editing: Matteo Simonetti

Visit https://www.thelancet.com/multimedia to learn more about our multimedia offering. 

Find the best science for better lives at https://www.thelancet.com/

Steatotic liver disease labels hinge on alcohol intake, but self-report is often inaccurate. In this episode, Aleksander Krag (Odense University Hospital) discusses a large Danish study using phosphatidylethanol (PEth), a direct blood biomarker of recent drinking, showing substantial underestimation and potential reclassification from MASLD to MetALD/ALD.

Click here to read the full article:

https://www.thelancet.com/journals/langas/article/PIIS2468-1253(25)00187-6/fulltext

Medical imaging and theranostics are revolutionising how we diagnose, treat, and understand disease. To meet this moment, The Lancet group is happy to announce the launch of, The Lancet Medical Imaging and Theranostics. 

You can visit https://www.thelancet.com/medical-imaging-theranostics to learn more.

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The Lancet Gastroenterology & Hepatology in conversation with...  is part of the Lancet Group podcast offering. 

Editorial team: editor-in-chief Rob Brierley, deputy editor Aisling O'Brien, and senior editor Bethany Gomersall

Podcast editing: Matteo Simonetti

Visit https://www.thelancet.com/multimedia to learn more about our multimedia offering. 

Find the best science for better lives at https://www.thelancet.com/

Can bacteria-free, sterile faecal filtrate match conventional faecal microbiota transplantation for recurrent C difficile infection? Dina Kao (University of Alberta) unpacks a landmark multicentre trial that tested this hypothesis, and we discuss what it tells us about the role of living organisms in the therapeutic effects of microbiota-based therapies.

Click here to read the full article: https://www.thelancet.com/journals/langas/article/PIIS2468-1253(25)00190-6/fulltext

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The Lancet Gastroenterology & Hepatology in conversation with...  is part of the Lancet Group podcast offering. 

Editorial team: editor-in-chief Rob Brierley, deputy editor Aisling O'Brien, and senior editor Bethany Gomersall

Podcast editing: Matteo Simonetti

Visit https://www.thelancet.com/multimedia to learn more about our multimedia offering. 

Find the best science for better lives at https://www.thelancet.com/

Do wheat or gluten trigger IBS symptoms? 

We spoke to Premysl Bercik about a randomised, double-blind, sham-controlled crossover trial that challenged adults with IBS—who reported benefit from a gluten-free diet—with wheat, gluten, or a gluten-free sham to test symptom and behavioural responses.

Click here to read the full article: https://www.thelancet.com/journals/langas/article/PIIS2468-1253(25)00090-1/fulltext

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The Lancet Gastroenterology & Hepatology in conversation with...  is part of the Lancet Group podcast offering. 

Editorial team: editor-in-chief Rob Brierley, deputy editor Aisling O'Brien, and senior editor Bethany Gomersall

Podcast editing: Matteo Simonetti

Visit https://www.thelancet.com/multimedia to learn more about our multimedia offering. 

Find the best science for better lives at https://www.thelancet.com/

Can a multi-metabolite blood test improve early pancreatic cancer detection? We spoke to Julia Mayerle about the METAPAC study, which sought to validate the ability of plasma metabolic signatures to find resectable tumors and reduce unnecessary invasive procedures in high-risk patients.

Read the full article:

https://www.thelancet.com/journals/langas/article/PIIS2468-1253(25)00056-1/fulltext?dgcid=buzzsprout_icw_podcast_June_25_langas

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The Lancet Gastroenterology & Hepatology in conversation with...  is part of the Lancet Group podcast offering. 

Editorial team: editor-in-chief Rob Brierley, deputy editor Aisling O'Brien, and senior editor Bethany Gomersall

Podcast editing: Matteo Simonetti

Visit https://www.thelancet.com/multimedia to learn more about our multimedia offering. 

Find the best science for better lives at https://www.thelancet.com/

How does acute kidney injury presentation and management differ globally for patients hospitalised with cirrhosis? 

We spoke to Salvatore Piano, corresponding author of the landmark International Club of Ascites GLOBAL AKI study, about new data on regional variations in severity, phenotype, treatment, and outcomes across 5 continents.

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https://www.thelancet.com/journals/langas/article/PIIS2468-1253(25)00006-8/fulltext?dgcid=buzzsprout_icw_podcast_generic_langas

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The Lancet Gastroenterology & Hepatology in conversation with...  is part of the Lancet Group podcast offering. 

Editorial team: editor-in-chief Rob Brierley, deputy editor Aisling O'Brien, and senior editor Bethany Gomersall

Podcast editing: Matteo Simonetti

Visit https://www.thelancet.com/multimedia to learn more about our multimedia offering. 

Find the best science for better lives at https://www.thelancet.com/

John Chia discusses the results of the ASCOLT trial, which explored the effect of aspirin after completion of standard adjuvant therapy for patients with colorectal cancer.

Read the full article:

https://www.thelancet.com/journals/langas/article/PIIS2468-1253(24)00387-X/fulltext?dgcid=buzzsprout_icw_podcast_generic_langas

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The Lancet Gastroenterology & Hepatology in conversation with...  is part of the Lancet Group podcast offering. 

Editorial team: editor-in-chief Rob Brierley, deputy editor Aisling O'Brien, and senior editor Bethany Gomersall

Podcast editing: Matteo Simonetti

Visit https://www.thelancet.com/multimedia to learn more about our multimedia offering. 

Find the best science for better lives at https://www.thelancet.com/

Hannes Hagström discusses a study investigating the feasibility of screening for advanced liver fibrosis alongside retina scanning in people with type 2 diabetes.

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The Lancet Gastroenterology & Hepatology in conversation with...  is part of the Lancet Group podcast offering. 

Editorial team: editor-in-chief Rob Brierley, deputy editor Aisling O'Brien, and senior editor Bethany Gomersall

Podcast editing: Matteo Simonetti

Visit https://www.thelancet.com/multimedia to learn more about our multimedia offering. 

Find the best science for better lives at https://www.thelancet.com/

Cathy Lu (University of Calgary) discusses a consensus statement on the use of intestinal ultrasound for assessing and monitoring small bowel strictures in Crohn's disease.

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The Lancet Gastroenterology & Hepatology in conversation with...  is part of the Lancet Group podcast offering. 

Editorial team: editor-in-chief Rob Brierley, deputy editor Aisling O'Brien, and senior editor Bethany Gomersall

Podcast editing: Matteo Simonetti

Visit https://www.thelancet.com/multimedia to learn more about our multimedia offering. 

Find the best science for better lives at https://www.thelancet.com/