Marion Moseby-Knappe talks about a prospective, international, observational biomarker study, within the Targeted Hypothermia versus Normothermia after Out-of-Hospital Cardiac Arrest (TTM2) trial, to compare four markers of brain injury for the prediction of functional outcome in patients after cardiac arrest using assays that can be analysed on clinically available equipment.

Click here to read the full article: https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(25)00363-7/fulltext

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Prof Sailesh Kotecha joins Diana Stanley to discuss the series on reframing prematurity-associated lung disease as a continuum that begins before birth and evolves throughout life.

Cick here to read the full series: 

Looking beyond bronchopulmonary dysplasia: prematurity-associated lung disease and its phenotypes
https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(25)00372-8/fulltext

Trajectories of prematurity-associated lung disease: lifelong lung health
https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(25)00371-6/fulltext

Management of prematurity-associated lung disease from infancy through to adulthood
https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(25)00369-8/fulltext

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Dr Neil Greening and Dr Hnin Aung join Diana Stanley to discuss a new multidimensional prognostic risk stratification model for COPD exacerbations.

click here to read the full article:
https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(25)00362-5/fulltext

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Dr Finn McQuaid and Dr Matthew Saunders join Arianna Colosio to discuss an analytical framework to describe potential causal relationships between climate change and tuberculosis.

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Toby Maher joins us to discuss results of a randomised, double-blind, placebo-controlled, proof-of-concept trial of ENV-101, an oral inhibitor of the hedgehog signalling pathway, in patients with idiopathic pulmonary fibrosis.

Read the full article:

https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(25)00239-5/fulltext?dgcid=buzzsprout_icw_podcast_September_25_lanres

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Professors Guy Brusselle and Celeste Porsbjerg join us to discuss their recent Series papers on asthma, which will be featured in a cross journal project with The Lancet, published to coincide with a Lancet journal session on asthma at ERS in Amsterdam. 

The Series aims to provide an overview of recent research advances related to asthma; to provide new insights into the genetics, prevention and risk factors for asthma; review advances arising as a result of the use of monoclonal antibody therapeutics; and assess remission in adult patients. Late breaking research will also be included within the journal session and linked to the Series.

Read the full Series:

https://www.thelancet.com/series-do/asthma-2025?dgcid=buzzsprout_icw_podcast_asthma25_lanres

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Diana Stanley, Deputy Editor at The Lancet Respiratory Medicine, is joined by Dr Joan Soriano to discuss a new series on the global epidemiology of respiratory disease, exploring the diagnostic challenges, global trends, and future directions for prevention.

Read the full Series:

https://www.thelancet.com/series-do/global-epidemiology-chronic-respiratory-disease?dgcid=buzzsprout_icw_podcast_lanrescrd25_lanres

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Carole Mitnick & Lorenzo Guglielmetti join Ari Colosio, deputy editor of The Lancet Respiratory Medicine, to discuss the ENDTB-Q trial to evaluate the efficacy and safety of a drug regiment to treat TB in individuals with pre-extensively drug-resistant tuberculosis.

Read the full article:

https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(25)00194-8/fulltext?dgcid=buzzsprout_icw_podcast_July_25_lanres

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This episode is in Italian. For the English version, please see the main feed.

Lorenzo Guglielmetti sul trial clinico ENDTB-Q per valutare l’efficacia e la sicurezza di un regime di farmaci per curare la tubercolosi in individui con tubercolosi pre-estesa farmaco-resistente.

Leggi l'articolo completo:

https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(25)00194-8/fulltext?dgcid=buzzsprout_icw_podcast_July_25_lanres

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Deputy editor Ari Colosio speaks with Dr. Laura Garriga-Grimau of the Val d’Hebron Hospital, Autonomous University of Barcelona. Dr. Garriga-Grimau discusses the first multi-country cohort study to describe the clinical features and standards of care for children and young people with bronchiectasis, drawing on data from the International Pediatric Bronchiectasis Registry.

Together, they examine key findings on regional differences in diagnosis, co-morbidities, clinical severity, and treatment practices across eight countries. Dr. Garriga-Grimau highlights the significant burden of bronchiectasis on patients and health systems, as well as the urgent need for earlier diagnosis, harmonised international guidelines, and more equitable research and care.

Read the full article:

https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(25)00089-X/abstract?dgcid=buzzsprout_icw_podcast_July_25_lanres

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