Christopher Vélez, MD and Noor Syed, MD discuss "The Efficacy and Safety of Tacrolimus in Reducing Inflammation and Need for Dilation," by Kukreja K, Kumar A, Camisa C, Jacobs J, Richter JE. Published in Clin Transl Gastroenterol, 2024 Dec 1;15(12):e00752.

Vasantham Chaudhary, MD and Elie Al Kazzi, MD, MPH discuss "Surveillance in inflammatory bowel disease: white light endoscopy with segmental re-inspection versus dye-based chromoendoscopy – a multi-arm randomised controlled trial (HELIOS)," by Te Groen M, Wijnands AM, den Broeder N, et al. Published in Gut 2025;75:547-556.

Leandro Sierra, MD and Joseph Lim, MD discuss "Early antiviral treatment with tenofovir alafenamide to prevent serious clinical adverse events in adults with chronic hepatitis B and moderate or high viraemia (ATTENTION): interim results from a randomised controlled trial,” by Lim Y. S., Yu M. L., Choi J., et al. Published in Lancet Gastroenterol Hepatol 2025; 10(4):295-305.

Rachael Hagen, MD and Joseph C. Anderson, MD, FACG discuss "Optimizing Bowel Preparation Quality for Colonoscopy: Consensus Recommendations by the US Multi-Society Task Force on Colorectal Cancer,” by Jacobson BC, Anderson JC, Burke CA, Dominitz JA, Gross SA, May FP, Patel SG, Shaukat A, Robertson DJ. Published in Am J Gastroenterol. 2025: 120(4):738-764.

Ellen Axenfeld, MD and Elie Al Zazzi, MD, MPH discuss "Phase 2 Trial of Anti-TL1A Monoclonal Antibody Tulisokibart for Ulcerative Colitis,” by Sands BE, Feagan BG, Peyrin-Biroulet L, et al and the ARTEMIS-UC Study Group. Published in N Engl J Med. 2024 Sep 26;391(12):1119-1129.

Editor-in-Chief Paul Y. Kwo, MD, FACG and Associate Editor Elie S. Al Kazzi, MD, MPH discuss "Tofacitinib in acute severe ulcerative colitis (TACOS): A randomized controlled trial," by Singh A, Goyal MK, Midha V, et al. Am J Gastroenterol 2024; 119 (7), 1365-1372.

Margaret J. Zhou, MD, MS and Timothy Yen, MD discuss "Impact of margin thermal ablation after endoscopic mucosal resection of large (≥20 mm) non-pedunculated colonic polyps on long-term recurrence," by O'Sullivan T, Mandarino FV, Gauci JL, et al. Gut. 2024 Dec 10;74(1):67-74.

Margaret J. Zhou, MD, MS and Timothy Yen, MD discuss "Germline CDH1 variants and lifetime cancer risk,” by Ryan CE, Fasaye G, Gallanis AF, et al. JAMA. 2024;332(9):722–729.

Philip Schoenfeld, MD, MSEd, MSc (Epi) and Bharati Kochar, MD, MS discuss “Phase 2 Trial of Anti-TL1A Monoclonal Antibody Tulisokibart for Ulcerative Colitis,” by Sands BE, Feagan BG, Biroulet LP, et al. N Engl J Med. 2024; 391: 1119-29.

Philip Schoenfeld, MD, MSEd, MSc (Epi) and Ahmad Abu-Heija, MBBS discuss “Cold Versus Hot Snare Endoscopic Resection of Large Nonpedunculated Colorectal Polyps: Randomized Controlled German CHRONICLE Trial,” by Steinbrück I, Ebigbo A, Kuellmer A, et al. Gastroenterology. 2024 Sep;167(4):764-777