Vasantham Chaudhary, MD and Elie Al Kazzi, MD, MPH discuss "Surveillance in inflammatory bowel disease: white light endoscopy with segmental re-inspection versus dye-based chromoendoscopy – a multi-arm randomised controlled trial (HELIOS)," by Te Groen M, Wijnands AM, den Broeder N, et al. Published in Gut 2025;75:547-556.

Leandro Sierra, MD and Joseph Lim, MD discuss "Early antiviral treatment with tenofovir alafenamide to prevent serious clinical adverse events in adults with chronic hepatitis B and moderate or high viraemia (ATTENTION): interim results from a randomised controlled trial,” by Lim Y. S., Yu M. L., Choi J., et al. Published in Lancet Gastroenterol Hepatol 2025; 10(4):295-305.

Rachael Hagen, MD and Joseph C. Anderson, MD, FACG discuss "Optimizing Bowel Preparation Quality for Colonoscopy: Consensus Recommendations by the US Multi-Society Task Force on Colorectal Cancer,” by Jacobson BC, Anderson JC, Burke CA, Dominitz JA, Gross SA, May FP, Patel SG, Shaukat A, Robertson DJ. Published in Am J Gastroenterol. 2025: 120(4):738-764.

Ellen Axenfeld, MD and Elie Al Zazzi, MD, MPH discuss "Phase 2 Trial of Anti-TL1A Monoclonal Antibody Tulisokibart for Ulcerative Colitis,” by Sands BE, Feagan BG, Peyrin-Biroulet L, et al and the ARTEMIS-UC Study Group. Published in N Engl J Med. 2024 Sep 26;391(12):1119-1129.

Editor-in-Chief Paul Y. Kwo, MD, FACG and Associate Editor Elie S. Al Kazzi, MD, MPH discuss "Tofacitinib in acute severe ulcerative colitis (TACOS): A randomized controlled trial," by Singh A, Goyal MK, Midha V, et al. Am J Gastroenterol 2024; 119 (7), 1365-1372.

Margaret J. Zhou, MD, MS and Timothy Yen, MD discuss "Impact of margin thermal ablation after endoscopic mucosal resection of large (≥20 mm) non-pedunculated colonic polyps on long-term recurrence," by O'Sullivan T, Mandarino FV, Gauci JL, et al. Gut. 2024 Dec 10;74(1):67-74.

Margaret J. Zhou, MD, MS and Timothy Yen, MD discuss "Germline CDH1 variants and lifetime cancer risk,” by Ryan CE, Fasaye G, Gallanis AF, et al. JAMA. 2024;332(9):722–729.

Philip Schoenfeld, MD, MSEd, MSc (Epi) and Bharati Kochar, MD, MS discuss “Phase 2 Trial of Anti-TL1A Monoclonal Antibody Tulisokibart for Ulcerative Colitis,” by Sands BE, Feagan BG, Biroulet LP, et al. N Engl J Med. 2024; 391: 1119-29.

Philip Schoenfeld, MD, MSEd, MSc (Epi) and Ahmad Abu-Heija, MBBS discuss “Cold Versus Hot Snare Endoscopic Resection of Large Nonpedunculated Colorectal Polyps: Randomized Controlled German CHRONICLE Trial,” by Steinbrück I, Ebigbo A, Kuellmer A, et al. Gastroenterology. 2024 Sep;167(4):764-777

Philip Schoenfeld, MD, MSEd, MSc (Epi) discusses “Combination of Carvedilol with Variceal Band Ligation in Prevention of First Variceal Bleed in Child-Turcotte-Pugh B and C Cirrhosis with High-Risk Oesophageal Varices: the ‘CAVARLY’ Trial,” by Tevethia HV, Pande A, Vijayaraghavan R, et al. Gut. 2024; 73: 1844-53.