Philip Schoenfeld, MD, MSEd, MSc (Epi) and Ahmad Abu-Heija, MBBS discuss “Efficacy and safety of linaclotide in treating functional constipation in paediatric patients: a randomised, double-blind, placebo-controlled, multicentre, phase 3 trial,” by Di Lorenzo C, Khlevner J, Rodriguez-Araujo G, et al. Lancet Gastroenterol Hepatol. 2024 Mar;9(3):238-250.

Philip Schoenfeld, MD, MSEd, MSc (Epi) and Bharati Kochar, MD, MS discuss “A biomarker-stratified comparison of top-down versus accelerated step-up treatment strategies for patients with newly diagnosed Crohn’s disease (PROFILE): a multicentre, open-label randomised controlled trial,” by Noor NM et al. Lancet Gastroenterol Hepatol. 2024; 9: 415-27.

Philip Schoenfeld, MD, MSEd, MSc (Epi) and Jacqueline Gaulin discuss “A Cell-free DNA Blood-Based Test for Colorectal Cancer Screening,” by Chung DC, Gray DM, Singh H, et al. N Engl J Med 2024; 390: 973-83.

Philip Schoenfeld, MD, MSEd, MSc (Epi) and Nicole Rich, MD, MSCS discuss “A phase 3, randomized controlled trial of resmetirom in NASH with liver fibrosis,” by Harrison SA, Bedossa P, Guy CD et al. NEJM 2024; 390(6): 497-509.

Philip Schoenfeld, MD, MSEd, MSc (Epi) and Sonali Paul, MD discuss “Association of Glucagon-Like Peptide-1 Receptor Agonists with Serious Liver Events among Patients with Type 2 Diabetes Mellitus: A Scandinavian Cohort Study,” Engstom A, Wintzell V, Melbye M, et al. Hepatology 2024; In Press.

Philip Schoenfeld, MD, MSEd, MSc (Epi) and Rahul Dalal, MD, MPH discuss “Maternal and Neonatal Outcomes in Vedolizumab and Ustekinumab Exposed Pregnancies: Results from the PIANO registry,” by Chugh R, Long MD, Jiang Y, Weaver KN, Beaulieu DB, Scherl EJ, Mahadevan U. Am J Gastroenterol. 2023 Oct 5. Epub ahead of print.

Philip Schoenfeld, MD, MSEd, MSc (Epi) and Jeffrey Lee, MD, MPH discuss “Endoscopic En Bloc Versus Piecemeal Resection of Large Nonpedunculated Colonic Adenomas: A Randomized Comparative Trial,” by Jacques J, Schaefer M, Wallenhorst T, et al. Ann Intern Med 2024; 177: 29-38.

Philip Schoenfeld, MD, MSEd, MSc (Epi) and Jacqueline Gaulin discuss “Association of Ultra-Processed Food Consumption with Colorectal Cancer Risk Among Men and Women,” by Wang L, Du M, Wang K, et al. BMJ 2022; 378:e068921.

Philip Schoenfeld, MD, MSEd, MSc (Epi) and Philip Okafor, MD, MPH discuss “Colorectal Cancer Screening Receipt Does Not Differ by 10-Year Mortality Risk among Older Adults,” by Liu PH, Singal AG, Murphy CC. Am J Gastroenterol 2024; 119: 353-63.

Philip Schoenfeld, MD, MSEd, MSc (Epi) and Timothy Yen, MD discuss “Personalised Surveillance for Serrated Polyposis Syndrome: Results from a Prospective 5-Year International Cohort Study,” by Bleijenberg AG, IJspeert JE, van Herwaarden YJ, et al. Gut 2020; 69: 112-21.