Howie and Harlan are joined by Lisa Suter, a rheumatologist and the senior director of the Quality Measurement Program at Yale’s Center for Outcomes Research & Evaluation. Harlan reflects on the meaning of Juneteenth and reports on a Yale-led report card on health equity; Howie comments on Surgeon General Vivek Murthy’s call for warning labels on social media. 

Links:

Juneteenth

National Museum of African American History & Culture: Juneteenth

Harlan Krumholz: “Excess Cardiovascular Mortality Among Black Americans 2000-2022: A JACC Report Card”

“JACC Report Card Highlights Inequities in CV Care, Death Rates”

Harlan Krumholz: “Excess Mortality and Years of Potential Life Lost Among the Black Population in the US, 1999-2020”

Lisa Suter

Center for Outcomes Research and Evaluation

National Institute of Arthritis and Musculoskeletal and Skin Disease: Arthritis

Lisa Suter: “Medical Decision Making in Patients With Knee Pain, Meniscal Tear, and Osteoarthritis”

Lisa Suter: “Projecting Lifetime Risk of Symptomatic Knee Osteoarthritis and Total Knee Replacement in Individuals Sustaining a Complete Anterior Cruciate Ligament Tear in Early Adulthood”

“Voices of DEI: Lisa Suter, MD”

Harlan Krumholz: “Association of door-to-balloon time and mortality in patients admitted to hospital with ST elevation myocardial infarction: national cohort study”

Harlan Krumholz: “Association of Racial and Socioeconomic Disparities With Outcomes Among Patients Hospitalized With Acute Myocardial Infarction, Heart Failure, and Pneumonia

An Analysis of Within- and Between-Hospital Variation”

The Surgeon General on Social Media 

“Surgeon General: Why I’m Calling for a Warning Label on Social Media Platforms”

“Social Media and Youth Mental Health: The U.S Surgeon General’s Advisory”

Kids Online Safety Act: Senator Richard Blumenthal

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Howie and Harlan are joined by Anna Reisman, a physician and writer who leads Yale’s Program for Humanities in Medicine. They discuss the gaps in care she encountered when her developmentally disabled sister was diagnosed with cancer, and her work reviewing the “dude wall” of portraits at Yale Medical School. Harlan asks what we’ve gained from a new definition of long COVID; Howie provides an update on the spread of the H5N1 bird flu. 

Links:

Defining Long COVID

“Federal Government, Clinicians, Employers, and Others Should Adopt New Definition for Long COVID to Aid in Consistent Diagnosis, Documentation, and Treatment”

National Academies: A Long COVID Definition

WHO: Post COVID-19 condition (Long COVID)

Anna Reisman

U.S. News: Yale University department rankings

Wikipedia: The Magic Mountain

Anna Reisman: “A doctor’s life, chronicled”

“Life on wheels” (Yale School of Medicine article on the documentary Rolling)

Anna Reisman: “Standard of Care”

“Academic Science Rethinks All-Too-White 'Dude Walls' Of Honor”

Wikipedia: Stanhope Bayne-Jones

“In Memoriam: Marjorie Rosenthal, MD '95, MPH 1967–2020”

“Yale Internal Medicine Residency Writers’ Workshop celebrates 20th anniversary”.

Bird Flu

FDA: Updates on Highly Pathogenic Avian Influenza (HPAI)

“CDC Reports A(H5N1) Ferret Study Results”

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Mitesh Rao, co-founder and CEO of OMNY Health, joins Howie and Harlan to discuss his entrepreneurial journey and how his company is creating a common layer of data connecting healthcare providers and researchers. Harlan reports on a study showing how many lives could be saved by improving quality of care; Howie reflects on the health consequences that have accompanied the legalization of cannabis. 

Links:

Quality and Lives Saved

“The business case for quality: estimating lives saved and harms avoided in a value-based purchasing model”

The CMS Innovation Center

NCQA: Hedis Measures

South Park: “Navigating the American Healthcare System”

Mitesh Rao

OMNY Health: Connect Data to Transform Lives

“OMNY Health announces $17 Million Raise to Lead the Next Generation of Real-World Data-Driven Decision-Making and Collaboration Across Healthcare”

Crunchbase: OMNY Health

“How Venture Capital Works”

UK Biobank: Enabling Scientific Discoveries that Improve Human Health

“The Robert Wood Johnson Clinical Scholars Program: Four Decades of Training Physicians as Agents of Change”

HIPAA: Health Information Privacy

Yale Innovation Summit

Cannabis and Health

“Justice Department Submits Proposed Regulation to Reschedule Marijuana”

“Changes in self-reported cannabis use in the United States from 1979 to 2022”

Cannabinoid Hyperemesis Syndrome

“Cannabis and Psychosis: Recent Epidemiological Findings Continuing the ‘Causality Debate’”

“High-potency marijuana highlights the risk of cannabis-induced psychiatric disorders”

Marijuana Addiction Facts: Is Marijuana Addictive?

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A special episode recorded at the Yale Innovation Summit, which brings together entrepreneurs and investors in the arts, biotech, climate, health, and tech. Howie and Harlan are joined by Josh Geballe, managing director of Yale Ventures, which hosts the summit; Mary Ann Melnick, site head at Biolabs New Haven; and Lee Schwamm, chief digital health officer at Yale New Haven Health System. 

Links:

Watch the event on YouTube.

Yale Ventures: Yale Innovation Summit

State of Connecticut: “Governor Lamont Announces Creation of the Innovation Clusters Program To Support Growth in Cutting-Edge Industries”

Yale Ventures: Venture Lab

BioLabs New Haven

The Provost’s Committee on Conflict of Interest

“Novel BioLaunch program to train New Haven residents for careers in biotech”

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Howie and Harlan are joined by Chima Ndumele of the Yale School of Public Health to discuss his research on structural changes to Medicaid that could keep vulnerable populations healthier. Harlan reports on the remarkable abilities of Google's latest medicine-focused AI; Howie reflects on a study showing the impact of race-neutral measures of lung function. 

Links:

AI and Medicine

“Capabilities of Gemini Models in Medicine”

Medicaid

Medicaid.gov

“10 Things to Know About Medicaid”

Supplemental Nutrition Assistance Program (SNAP)

“Long-Term Stability of Coverage Among Michigan Medicaid Beneficiaries: A Cohort Study”

“Unwinding And The Medicaid Undercount: Millions Enrolled In Medicaid During The Pandemic Thought They Were Uninsured”

Chima Ndumele: “Variation in Health Outcomes: The Role of Spending on Social Services, Public Health, and Health Care, 2000–09”

Chima Ndumele: “In Medicaid Managed Care Networks, Care Is Highly Concentrated Among A Small Percentage Of Physicians”

“N.C. developing plan to improve Medicaid participants’ job prospects”

“Yale School of Public Health Graduates Urged to Adopt a “Healthy Disregard for the Impossible”

Race and Lung Function

“Implications of Race Adjustment in Lung-Function Equations”

Harlan Krumholz: “Association of Racial and Socioeconomic Disparities with Outcomes among Patients Hospitalized with Acute Myocardial Infarction, Heart Failure, and Pneumonia. An Analysis of Within- and Between-Hospital Variation”

“Q&A: Harlan Krumholz on hospital readmissions”

Health & Veritas Live on May 30

Join Howie and Harlan in person at the Yale Innovation Summit.

Watch live on YouTube.

Learn more about the MBA for Executives program at Yale SOM.

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Howie and Harlan are joined by Ruth Katz, executive director of the Aspen Institute’s Health, Medicine & Society Program and a former Capitol Hill staffer, to discuss her work on the Affordable Care Act and other major healthcare laws. Harlan reflects on a study showing that using different analytical approaches to the same data can lead to a wide range of conclusions; Howie reports on a wave of dangerous infections caused by stem cell treatments at clinics in Mexico. 

Links:

Reproducible Research

“Grilling the data: application of specification curve analysis to red meat and all-cause mortality”

“Many Analysts, One Data Set: Making Transparent How Variations in Analytic Choices Affect Results”

Ruth Katz

“Reflecting on Past Accomplishments to Make History Moving Forward: The NIH Revitalization Act of 1993 and the New Office of Autoimmune Disease Research

“Thousands Believe Covid Vaccines Harmed Them. Is Anyone Listening?”

National Vaccine Injury Compensation Program

Health Resources and Services Administration: Vaccine Injury Table

“Brilliant Minds. Bold Approaches. Better Health. Aspen Ideas: Health Announces Programming Themes for 2024”

Medical Tourism and Stem Cell Treatments

“Stem cell injections in Mexico can be hazardous. Report identifies US victims”

CDC: Medical Tourism

Health & Veritas Live on May 30

Join Howie and Harlan in person at the Yale Innovation Summit

Watch live on YouTube

Learn more about the MBA for Executives program at Yale SOM.

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Howie and Harlan are joined by Greg Licholai, a Yale SOM lecturer and biotech entrepreneur, to discuss his career and his work at the contract research organization ICON, which performs clinical trials for pharmaceutical companies. Harlan reports on new research illustrating the dangerous consequences of asking patients to share the costs of life-saving drugs; Howie provides the good news and the bad news from the annual Medicare Trustees Report. 

Links:

Cost-Sharing and Mortality

“The Health Costs Of Cost-Sharing”

“The Boys of January”

Greg Licholai

ICON plc

Greg Licholai in Forbes

Boston Children's Hospital: Sickle Cell Disease

The State of the Medicare Trust Fund

Medicare: Coverage Gap

2024 Medicare Trustees Report

KFF: FAQs on Medicare Financing and Trust Fund Solvency

KFF: What to Know about Medicare Spending and Financing

Health & Veritas Live on May 30

Join Howie and Harlan in person at the Yale Innovation Summit

Watch live on YouTube

Learn more about the MBA for Executives program at Yale SOM.

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Howie and Harlan discuss health and healthcare headlines. From flatlining telehealth to Walmart closing retail clinics to months-long waits for healthcare appointments, they try to untangle the challenges in delivering healthcare. Also considered, H5N1 bird flu increasing the risks of drinking unpasteurized milk, promising research on open-source moderation of misinformation on social media.

Links:

Yale Repertory Theater | The Far Country

CDC | H5N1

“US bird flu outbreak spreads to chickens, cattle, raises concerns over human infections”

“Raw Milk Is Being Legalized in More States. Is It Safe?”

“Recipe for a Healthy Gut: Intake of Unpasteurised Milk Is Associated with Increased Lactobacillus Abundance in the Human Gut Microbiome“

“Long-time Teladoc leader departs as virtual care provider struggles with post-COVID tumble”

“Teladoc sinks $13.7B loss in 2022 tied to plummeting value of Livongo acquisition”

“Optum layoffs: naviHealth CEO out; Virtual care business shuttered”

Connecticut | Certificate of Needs

Characteristics of X (Formerly Twitter) Community Notes Addressing COVID-19 Vaccine Misinformation

“Walmart is closing down its health centers. What’s that mean for Amazon, Walgreens and CVS?”

“Walgreens narrows profit outlook for 2024, takes $6B hit in Q2 from VillageMD investment”

“Why It Takes Forever to Get a Doctor’s Appointment”

Yale Innovation Summit 2024

Link for the Health & Veritas Livestream at the Yale Innovation Summit

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Howie and Harlan are joined by Arthur Caplan, Drs. William F. and Virginia Connolly Mitty Professor of Bioethics and founding head of the division of medical ethics at NYU Grossman School of Medicine, to discuss the ethical failings of the pharmaceutical industry and how a community-focused ethos prioritizing justice and protection of the vulnerable would have reshaped the COVID response. Harlan reports on developments in synthetic proteins. Howie recognizes World Malaria Day.

Links:

Division of Medical Ethics: NYU Langone

“‘You’ve got bad blood’: The horror of the Tuskegee syphilis experiment”

“When Evil Intrudes”

“Surgeons Perform World’s First Combined Heart Pump And Pig Kidney Transplant—Latest Breakthrough Involving Pig Organ”

“Biden trolls Trump on injecting bleach anniversary”

Frequently Asked Questions on Oregon’s Death With Dignity Act (DWDA)

“A quiet revolution in organ transplant ethics”

Center for Healthcare Ethics: The Provider-Patient Relationship

“Ex-Stanford President’s AI Drug Startup Pulls In $1 Billion in Commitments”

“Protein wrangler, serial entrepreneur, and community builder: Inside David Baker’s brain”

Baker Lab: Home Page

“Atomically accurate de novo design of single-domain antibodies”

National Cancer Institute: Definition of a Monoclonal Antibody

Malaria: World Health Organization 

CDC: Malaria’s Impact Worldwide

UNICEF: Ten things you didn’t know about malaria

Yale Innovation Summit 2024

Link for the Health & Veritas Livestream at the Yale Innovation Summit

Learn more about the MBA for Executives program at Yale SOM.

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Howie and Harlan are joined by Scott Berkowitz ’03, cardiologist and chief population health officer at Johns Hopkins Medicine, to discuss the necessity of moving from fee-for-service to value-based care delivery to improve outcomes for all. Harlan highlights the dangers of misinformation about Ivermectin. Howie reports on the potential conflicts of interest created by device manufacturers’ payments to cardiologists.

Links:

Johns Hopkins Medicine: Home

Johns Hopkins Community Health Partnership

“Association of a Care Coordination Model With Health Care Costs and Utilization”

“Planning for the Future of Population Health: The Johns Hopkins Medicine Experience”

“Califf’s long day on Capitol Hill”

“The FDA Deleted Its Viral Ivermectin Tweets. Now There’s Even More Misinformation.”

“Philly Nonprofit Awarded $48 Million to Apply AI in Search for New Uses for Approved Drugs

Posted on March 12, 2024”

“Effect of Early Treatment with Ivermectin among Patients with Covid-19”

“Effect of Ivermectin vs Placebo on Time to Sustained Recovery in Outpatients With Mild to Moderate COVID-19”

“Effect of Higher-Dose Ivermectin for 6 Days vs Placebo on Time to Sustained Recovery in Outpatients With COVID-19”

“Systematic review and meta-analysis of ivermectin for treatment of COVID-19: evidence beyond the hype”

Ivermectin and Covid

“FDA settles lawsuit over ivermectin content that doctors claimed harmed their practice”

“Intravascular Microaxial Left Ventricular Assist Device Manufacturer Payments to Cardiologists and Use of Devices”

“Impact of Industry Payments on Prescribing Patterns for Tumor Necrosis Factor Inhibitors Among Medicare Beneficiaries”

Yale Innovation Summit 2024

Learn more about the MBA for Executives program at Yale SOM.

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