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In this episode, Marcus celebrates Nashville SC’s Supporters’ Shield and he and Vic dig into federal debt hitting 100% of GDP, accelerating inflation and a Fed holding steady before the midterms, new raises for ClarityCare and Midstream Health, the PBM transparency rule, Medicaid work requirements, RFK Jr. greenlighting unapproved peptides, Centene’s layoffs, big tech’s prior auth pledge, HCA’s ACA losses versus Tenet’s beat, UHS’s soft volumes, Bon Secours’ $5.7B bid for Surgery Partners, Risant’s Integris deal, Lilly’s retatrutide win and 39% revenue growth, the ChatGPT seizure medication lawsuit, DTCC’s tokenization launch, Anthropic’s IPO prospectus, Doximity’s dosing study, and how AI quietly shapes expert judgment with insights into market trends, policy changes, and technological innovations shaping the future of health and money.
Chapters
0:00 Introduction
3:17 Federal debt hits 100% of GDP for the first time since 1946 ↳
https://www.wsj.com/economy/federal-debt-hits-100-of-gdp-585d3cb0
6:05 PCE inflation accelerates in September ↳
https://www.wsj.com/economy/central-banking/pce-inflation-accelerated-last-month-5f72a43f
6:37 Fed holds rates as Cook and Hammack dissent in favor of a hike ↳
https://www.wsj.com/economy/central-banking/federal-reserve-interest-rate-decision-df120667
7:57 ClarityCare raises $16.5M to speed up prior authorizations ↳
https://medcitynews.com/2026/10/claritycare-raises-16-5m-to-speed-up-prior-authorizations/
8:58 Midstream Health secures $20M for its health system financial operations AI platform ↳
https://www.modernhealthcare.com/health-tech/ai/mh-tracking-ai-healthcare-live-updates
9:48 PBMs face new transparency mandates under Labor Department rule ↳
https://www.modernhealthcare.com/politics-regulation/mh-labor-department-pbm-transparency-rule
10:51 Court voids CMS's Medicaid medical frailty work requirement policy ↳
https://www.modernhealthcare.com/politics-regulation/mh-court-cms-medicaid-medical-frailty
12:06 RFK Jr. allows unapproved peptides on the market ↳
https://www.wsj.com/health/healthcare/rfk-jr-allows-unapproved-peptides-on-the-market-9cf4a6d3
15:44 Centene progresses on profit recovery, cuts 6,000 jobs ↳
https://www.healthcaredive.com/news/centene-progresses-profit-recovery-cuts-workforce-by-6k/872816/
16:46 Five major companies pledge faster electronic prior authorizations ↳
https://www.healthcaredive.com/news/five-major-companies-pledge-faster-electronic-prior-authorizations/833848/
18:40 HCA's bottom line suffers as ACA coverage losses mount ↳
https://www.healthcaredive.com/news/hcas-bottom-line-suffers-aca-coverage-losses-mount/873032/
20:52 Tenet sails past Q3 earnings estimates, boosts 2026 guidance ↳
https://www.fiercehealthcare.com/providers/tenet-healthcare-sails-past-q3-earnings-estimates-boosts-2026-guidance
22:28 Softer surgery volumes dampen UHS's Q3 earnings ↳
https://www.healthcaredive.com/news/softer-surgery-volumes-hospital-woes-dampened-uhs-q3-earnings/873190/
23:58 Bon Secours affiliate makes $5.7B bid for Surgery Partners ↳
https://www.healthcaredive.com/news/bon-secours-affiliate-5-7-billion-bid-surgery-partners/872887/
25:49 Risant Health to acquire Integris Health ↳
https://www.modernhealthcare.com/mergers-acquisitions/mh-risant-health-integris-kaiser-permanente
29:19 Lilly's triple-G drug retatrutide tops Ozempic in head-to-head trial ↳
https://medcitynews.com/2026/10/eli-lilly-retatrutide-type-2-diabetes-glp-1-gip-glucagon-metabolic-ozempic-lly/
30:51 Eli Lilly's revenue climbs on demand for obesity drugs ↳
https://www.wsj.com/health/pharma/eli-lilly-revenue-climbs-on-demand-for-mounjaro-zepbound-a6d810a5
31:53 Family blames ChatGPT after woman stops her seizure medication ↳
https://gizmodo.com/a-woman-asked-chatgpt-how-to-get-off-her-seizure-meds-her-family-says-it-killed-her-2000832591
36:41 DTCC brings $30 trillion in securities closer to blockchain with major banks ↳
https://www.coindesk.com/business/2026/10/28/wall-street-backbone-dtcc-brings-usd30-trillion-securities-closer-to-blockchain-with-major-banks
38:00 The biggest takeaways from Anthropic's IPO prospectus ↳
https://www.wsj.com/risk-compliance-journal/the-morning-risk-report-the-biggest-takeaways-from-anthropics-ipo-prospectus-f786ea5e
49:01 Popular AI models get medication doses wrong, some dangerously ↳
https://www.healthcaredive.com/news/popular-ai-models-get-medication-doses-wrong-some-dangerously-doximity/873207/
51:14 Anthropic study finds expert judgment can be easily hacked by AI ↳
https://gizmodo.com/expert-judgement-can-be-easily-hacked-by-ai-anthropic-study-finds-2000832143
#HealthPolicy #FederalReserve #PBMTransparency #Medicaid #Peptides #PriorAuthorization #MedicareAdvantage #ACA #ProviderConsolidation #EliLilly #GLP1 #Pharma #Tokenization #HealthTech #AI #Anthropic #Healthcare #HealthFurther
In this episode, Marcus is back from Oaxaca and he and Vic dig into Wall Street's nerves over Meta's AI capex and what rising rates and the Iran war mean for the AI buildout, jobless claims that don't match what we're seeing on the ground, BMS leading Pathos AI's $237M Series E and the biotech surge, OMass's $310M raise for a rare endocrine disorder, the Trump administration tying rural health dollars to Certificate of Need rollbacks, Treasury sweeping biotech into the COINS Act while sparing Big Pharma's China deals, friend of the show Rick Abramson on why the FDA should assess GenAI tools like physicians, family health plan costs climbing past $28K, Elevance's raised guidance, what new insurer entrants think they can do differently, Abbott's nutrition spinoff, the Quest Diagnostics breach, violence driving nurses from the profession, Moderna's leaked cancer vaccine data, GSK's hepatitis B approval, GLP-1s and breastfeeding, the OCC's GENIUS Act stablecoin rules, the AI-found PHP bug putting 70% of websites at risk, unvetted AI agents inside bank accounts, and why Anthropic can't afford to delay its IPO — with insights into market trends, policy changes, and technological innovations shaping the future of health and money.
Chapters
0:00 Introduction
3:45 Meta's hunt for AI capital rattles Wall Street ↳
https://www.wsj.com/finance/stocks/metas-hunt-for-ai-capital-strikes-a-raw-nerve-on-wall-street-e2de1601
13:58 US jobless claims return to a downward trend ↳
https://www.wsj.com/economy/jobs/u-s-jobless-claims-return-to-downward-trend-9ba853fc
16:26 BMS leads Pathos AI's $237M Series E alongside an Alzheimer's collaboration ↳
https://www.fiercebiotech.com/biotech/pathos-ai-closes-237m-series-e-heels-bms-alzheimers-link
19:19 OMass raises $310M for a rare endocrine disorder drug ↳
https://medcitynews.com/2026/10/startup-omass-rare-disease-endocrine-hormone-melanocortin-2-mc2-cah/
20:19 Trump dangles rural health funds to push states to change CON laws ↳
https://www.modernhealthcare.com/politics-regulation/mh-trump-rural-health-certificate-need-laws/
29:06 Treasury sweeps biotech into proposed COINS Act restrictions, spares Big Pharma's China licensing ↳
https://www.fiercebiotech.com/biotech/treasury-sweeps-biotech-proposed-coins-act-restrictions-spares-big-pharma-china-licensing
35:35 FDA's Rick Abramson: GenAI tools will need to be assessed like a physician ↳
https://medcitynews.com/2026/10/fda-official-believes-genai-enabled-tools-will-need-to-be-assessed-like-a-physician/
38:46 Family health plan costs rise as employers shift more to workers ↳
https://www.wsj.com/health/healthcare/in-era-of-runaway-health-inflation-employers-scramble-to-keep-costs-in-check-fdae86df
42:04 Elevance raises full-year guidance on lower medical costs ↳
https://www.modernhealthcare.com/insurance/mh-elevance-earnings-third-quarter-2026-outlook
43:27 What new insurer entrants think they can do differently ↳
https://www.modernhealthcare.com/insurance/mh-health-systems-insurance-plans-included-nice
50:56 Abbott to carve out its nutrition business ↳
https://www.wsj.com/health/healthcare/abbott-to-carve-out-nutrition-business-into-independent-company-e9384a15
51:57 Quest Diagnostics' test-results system breached in cyberattack ↳
https://www.fiercebiotech.com/medtech/quest-diagnostics-test-results-system-breached-yet-another-medtech-cyberattack
55:35 Nurses are in high demand, but they're quitting in droves ↳
https://www.wsj.com/health/healthcare/nurses-are-in-high-demandbut-theyre-quitting-in-droves-d8ead94f
1:01:23 Moderna shares fall after cancer vaccine data leaks on social media ↳
https://www.wsj.com/health/pharma/moderna-cancer-vaccine-data-leaks-early-shares-plummet-f6bc4b4f
1:04:27 GSK wins FDA approval for hepatitis B drug Hibsago ↳
https://medcitynews.com/2026/10/gsk-chronic-hepatitis-b-fda-approval-bepirovirsen-hibsago-functional-cure-ionis-aso-ions/
1:05:21 Weight-loss drugs may be OK while breastfeeding ↳
https://www.wsj.com/health/wellness/a-no-no-during-pregnancy-weight-loss-drugs-may-be-ok-while-breast-feeding-d2e72baf
1:07:09 The OCC finalizes GENIUS Act stablecoin rules ↳
https://decrypt.co/381502/occ-finalizes-genius-act-stablecoin-rules-ahead-of-january-deadline
1:10:57 AI finds a PHP bug that puts up to 70% of the world's websites at risk ↳
https://www.wsj.com/tech/cybersecurity/ai-just-found-a-bug-that-puts-up-to-70-of-the-worlds-websites-at-risk-fd0902ea
1:15:18 Unvetted AI agents are operating inside US bank accounts ↳
https://www.axios.com/2026/10/22/ai-agents-banks-unauthorized-accounts-access
1:18:09 Why Anthropic can't afford to delay its IPO ↳
https://www.axios.com/2026/10/21/anthropic-ipo-ai-costs
#AICapex #Meta #JobsReport #Economy #VentureCapital #HealthTechVC #Biotech #CertificateOfNeed #RuralHealth #COINSAct #FDA #GenAI #HealthcareCosts #HealthInsurance #Cybersecurity #Nursing #Moderna #GLP1 #Stablecoins #GENIUSAct #AIAgents #Anthropic
In this episode, Vic is joined by Emily Evans, sitting in for Marcus, to talk through her book on the two competing philosophies that have shaped American healthcare, a September jobs report shaped by shifting immigration dynamics, Fed minutes and the return of bond market volatility, Healthleap's AI for flagging undiagnosed hospital patients, Matchpoint Therapeutics' $150M raise and the promise of immune-based therapies, the FTC's warning letters to 24 health systems over price transparency, HHS's plan to allow some unapproved peptides as Chinese manufacturers flood the U.S. with bootleg versions, Texas AG Ken Paxton's probe of UnitedHealth, the "battle of the AIs" between payers and providers, GE HealthCare's $945M bet on radiopharmaceuticals, the optogenetics Nobel Prize, influencers urging patients not to pay their medical bills, tokenized stocks and stablecoin remittances, Biohub's $1.8B push for AI-ready biological data, OpenAI's 722 math proofs, and the enterprise AI price war between OpenAI and Anthropic — with insights into market trends, policy changes, and technological innovations shaping the future of health and money.
Chapters
0:00 Introduction
0:47 Emily's book: universal care vs. incrementalism in American healthcare
3:46 September jobs report: hiring trudges along ↳
https://www.wsj.com/economy/jobs/september-jobs-report-unemployment-6b6d6643
6:48 Fed minutes, the deficit and the return of bond market volatility ↳
https://www.wsj.com/economy/central-banking/fed-minutes-signal-further-rate-increase-this-year-but-no-urgency-for-october-hike-54ec759f
10:13 Healthleap raises $38M for AI that flags hospital patients who need a closer look ↳
https://techcrunch.com/2026/10/07/healthleap-raises-38m-for-its-ai-that-flags-hospital-patients-who-may-need-a-closer-look/
15:02 Matchpoint Therapeutics raises $150M Series B ↳
https://www.fiercebiotech.com/biotech/matchpoint-nets-150m-series-b-take-covalent-med-clinic
19:31 Parakeet Health raises $10M for conversational AI ↳
https://medcitynews.com/2026/10/parakeet-health-secures-10m-for-conversational-agentic-platform/
23:51 The FTC warns 24 health systems over price transparency ↳
https://www.beckershospitalreview.com/legal-regulatory-issues/the-ftcs-healthcare-crackdown-9-things-to-know/
31:14 HHS plans a stopgap to allow some unapproved peptides ↳
https://www.beckershospitalreview.com/glp-1s/hhs-plans-stopgap-to-allow-sales-of-some-unapproved-peptides-washington-post/
36:01 Texas AG Ken Paxton investigates UnitedHealth over care denials ↳
https://www.healthcaredive.com/news/texas-ken-paxton-unitedhealth-investigation-care-denials/832221/
38:22 Fitch: humans will stay in the loop on AI prior auth ↳
https://www.beckershospitalreview.com/finance/revenue-cycle-management/fitch-human-review-in-ai-prior-authorization-denials-likely-here-to-stay/
40:27 GE HealthCare buys SOFIE for nearly $1B ↳
https://www.wsj.com/health/healthcare/ge-healthcare-to-buy-sofie-for-nearly-1-billion-to-grow-medical-imaging-business-cfca0318
42:56 The outpatient shift accelerates as hospital margins rebound ↳
https://www.healthcaredive.com/news/outpatient-shift-accelerates-hospital-margins-rebound-strata/832490/
44:51 Nobel Prize in Physiology or Medicine goes to optogenetics ↳
https://www.wsj.com/science/trio-awarded-nobel-prize-in-physiology-or-medicine-for-neuroscience-discoveries-55005d95
47:06 Chinese makers of fentanyl ingredients now sell bootleg peptides ↳
https://www.wsj.com/health/pharma/chinese-makers-of-fentanyl-ingredients-now-sell-bootleg-peptides-to-americans-c383160b
50:14 The influencers on a mission to stop people from paying medical bills ↳
https://www.wsj.com/health/healthcare/these-influencers-are-on-a-mission-to-stop-people-from-paying-medical-bills-4843da3d
1:00:14 Securitize launches tokenized stock trading ↳
https://www.wsj.com/livecoverage/stock-market-today-dow-sp-500-nasdaq-10-08-2026/card/securitize-launches-tokenized-stock-trading-for-u-s-investors-dUqrm7mXGjwUrAdo4x6M
1:01:46 Samsung adds USDC cross-border payments to Galaxy Wallet ↳
https://cryptorank.io/news/feed/4d678-samsung-wallet-usdc-solana
1:03:21 Biohub, DOE and NIH back $1.8B in biological data for AI ↳
https://www.wsj.com/tech/ai/zuckerbergs-biohub-partners-with-doe-nih-to-invest-1-8-billion-in-biological-data-for-ai-models-f8d5f799
1:08:34 OpenAI's math breakthrough points beyond math ↳
https://www.axios.com/2026/10/08/openai-math-proofs-ai-model
1:12:20 The AI price war heats up as OpenAI gains on Anthropic ↳
https://www.wsj.com/tech/ai/the-ai-price-war-is-heating-upand-openai-is-gaining-ground-on-anthropic-48b8525b
#HealthcarePolicy #PriceTransparency #FTC #Peptides #FDA #HHS #UnitedHealth #PriorAuth #Radiopharmaceuticals #NobelPrize #Optogenetics #MedicalDebt #JobsReport #FederalReserve #VentureCapital #HealthTechVC #Tokenization #Stablecoins #AI #OpenAI #Anthropic
In this episode, Marcus and Vic bring the headlines back: why 10-year Treasury yields at their highest level since 2002 signal a fiscal problem healthcare can't ignore, how Trump's agenda has pushed up rates and inflation, Neko Health's $700M bet on whole-body scanning and Precision Neuroscience's $250M Series D, the GLOBE rule's shrinking Medicare savings, the SEC opening private markets to ordinary investors, HHS's push to redesign clinical trials, Cigna's AI-driven savings, UPMC's acquisition of Trinity Health, Epic's pause to focus on cybersecurity, the FDA panel backing Grail's Galleri test, the FTC's probe of OpenAI and Anthropic, and the arrival of consumer AI agents like OpenAI's Dots with insights into market trends, policy changes, and technological innovations shaping the future of health and money.
Chapters
0:00 Introduction
2:20 August PCE inflation reading ↳
https://www.wsj.com/livecoverage/stock-market-today-dow-sp-500-nasdaq-09-30-2026/card/what-to-know-about-today-s-pce-index-YnU6yGlmCpHowo8u4TSP
3:16 US bond yields hit their highest level since 2002 ↳
https://www.nytimes.com/2026/10/01/business/bond-yields-10-year-treasury.html
7:28 How Trump's economic moves drove rates and inflation higher ↳
https://www.wsj.com/economy/trump-economy-inflation-jobs-724e4da8
10:15 Neko Health's $700M bet on whole-body scanning ↳
https://techcrunch.com/podcast/the-investor-behind-neko-healths-700m-bet-on-scanning-your-whole-body/
12:54 Precision Neuroscience's $250M Series D for brain-computer interfaces ↳
https://www.fiercebiotech.com/medtech/precision-neuroscience-taps-250m-series-d-funding-brain-computer-interface
16:29 CMS finalizes the GLOBE rule as projected savings shrink ↳
https://endpoints.news/cms-finalizes-globe-medicare-demo-but-savings-trail-projections/
20:56 The SEC expands private-market access for ordinary investors ↳
https://www.wsj.com/pro/private-equity/sec-moves-to-give-ordinary-investors-more-access-to-private-equity-d4108681?st=ZNfSmp&reflink=desktopwebshare_permalink
23:32 Public market headwinds: Oura's paused IPO and Anthropic's losses ↳
https://www.wsj.com/tech/oura-postpones-ipo-over-market-uncertainty-49d49791
https://decrypt.co/379605/anthropic-lost-42-billion-last-year-wants-ipo-2-trillion
30:40 HHS launches a project to speed up clinical trials ↳
https://www.axios.com/2026/09/30/hhs-clinical-trials-redesign
33:52 Cigna expects $3B in savings from AI and automation ↳
https://www.modernhealthcare.com/insurance/mh-cigna-investor-day-ai-pharmacy
34:30 UPMC acquires CommonSpirit's Trinity Health ↳
https://www.modernhealthcare.com/mergers-acquisitions/mh-upmc-trinity-health-system-commonspirit
35:30 Epic pauses product development to focus on cybersecurity ↳
https://www.modernhealthcare.com/health-tech/mh-epic-systems-pause-product-development-ai
37:15 The FDA panel on Grail's Galleri test and the Medicare question ↳
https://www.wsj.com/health/healthcare/a-cancer-test-has-investors-betting-big-but-will-insurers-pay-75d3bc60
42:00 The FTC probes OpenAI and Anthropic over AI safety ↳
https://www.axios.com/2026/09/30/ftc-openai-anthropic-ai-safety-investigation
53:01 OpenAI launches Dots and the rise of consumer AI agents ↳
https://techcrunch.com/2026/09/29/openai-launches-dots-its-bubbly-agentic-avatar/
#NationalDebt #BondYields #FiscalDominance #Inflation #Economy #HealthcareCuts #CMS #FDA #Grail #ClinicalTrials #VentureCapital #HealthTechVC #PrivateMarkets #SEC #HealthSystemMandA #Cybersecurity #AI #AISafety #AIAgents #HealthcarePolicy
In this episode, Marcus and Vic set the headlines aside for UN General Assembly week and test their worldviews across every theme of the show: why the national debt and fiscal dominance matter more than the Fed, what a multipolar world means for healthcare funding, why neither party can stop the cuts that started with HR1, how AI is reshaping venture capital, the FDA as the administration's bright spot, stablecoin rails as a challenger to claims clearinghouses, the frontier labs' communication and business-model problems, and a friendly debate over whether AI will cost jobs or spark a new wave of entrepreneurship — with insights into market trends, policy changes, and technological innovations shaping the future of health and money.
Key Topics
Why covering the Fed feels less meaningful in an era of fiscal dominance
Debt-to-GDP nearing World War II levels and the cost of debt service
UN General Assembly week, diversification, and the shift to a multipolar world
Why healthcare rarely talks about the national debt — and why HR1 is just the beginning
The Fourth Turning, Ray Dalio's debt cycles, and a coming day of reckoning
The midterms, legislative vs. executive power, and why neither party can fix inflation
What the Paramount deal says about consolidation and corporate leverage
Health systems cutting vendors and what that means for startups
AI lowering the capital needed to build a company — and LP-driven mega-funds
Impact investing, value-based care, and the timeline problem
FDA and CMS policy: the inpatient-only list, value-based care, and telehealth limbo
Stablecoin rails and programmatic claims as a shot at healthcare's $1 trillion settlement cost
Frontier AI labs, the gain-of-function analogy, and cybersecurity over extinction talk
AI and jobs: middle management, entrepreneurship, and community resilience
Chapters
0:00 Introduction and episode overview
2:04 The shifting focus on the economy and debt levels
3:59 Geopolitical changes and the move towards a multipolar world
7:51 Healthcare system challenges and policy implications
23:03 Venture capital trends and health tech investments
35:00 Policy updates and regulatory environment in healthcare
38:00 The role of AI and Web3 in industry transformation
53:01 The societal impact of AI and future job markets
1:02:00 Concluding thoughts and future outlooks
#NationalDebt #FiscalDominance #Economy #Inflation #Midterms #VentureCapital #HealthTech #Biotech #HealthSystems #CMS #FDA #ValueBasedCare #Telehealth #RevenueCycle #Web3 #Stablecoins #Blockchain #AI #AISafety #FutureOfWork #Entrepreneurship #HealthcarePolicy
In this episode, we explore Vic's takeaways from Nashville Healthcare Sessions and the OpenAI-HCA partnership, a Fed rate hike to 3.75%-4% under new Chairman Kevin Warsh, a wave of nine-figure health rounds, the hollowing out of hospital margins and price transparency compliance, a potential CRISPR successor called Viper, and OpenAI's $1.2 trillion valuation push amid new AI safety disclosures — with insights into market trends, policy changes, and technological innovations shaping the future of health and money.
Key Topics
Nashville Healthcare Sessions recap and the OpenAI-HCA partnership
Jobless claims fall to 196K, but the labor-force participation rate tells a different story US housing starts slip as affordable inventory stays stuck
The Fed raises rates 25bps to 3.75%-4% under new Chairman Kevin Warsh
VC Rundown: Thatch hits a $1B valuation, Sling raises $123M, and Evvy raises $40M
CMS expands the ACCESS model's chronic conditions for 2027
More than half of hospitals still aren't compliant with price transparency rules
Hospital operating margins fall to 1.4% amid outpatient slowdowns
The widening mental-health and turnover gap among physicians and Gen Z clinicians
Viper: a newly discovered gene-editing system that may outperform CRISPR
GSK commits up to $750M for a new multiple myeloma therapy
Tokenized securities get a 5-year SEC exemption after the Clarity Act fails in the Senate
Circle launches its ARC stablecoin blockchain with BlackRock and Visa
OpenAI's new AI safety incidents, its $1.2 trillion valuation push, and the case for AI product liability
AI as a co-scientist: accelerating drug discovery at Stanford
Chapters
0:00 Introduction — Vic recaps Nashville Healthcare Sessions and the OpenAI-HCA partnership
2:13 Marcus on a loaded week in Nashville — family, civic work, and a strong portfolio
4:21 Jobless claims fall to 196K, but the participation rate tells the real story
6:49 US housing starts slip as affordable inventory stays stuck
8:30 The Fed raises rates 25bps to 3.75%-4% under Chairman Kevin Warsh
12:50 VC Rundown: Thatch secures $108M Series C, hits $1B valuation
14:31 Sling raises $123M Series C for an oral GLP-1 rival
15:03 Evvy raises $40M for vaginal microbiome research
15:55 CMS adds more chronic conditions to the ACCESS model for 2027
17:29 More than half of hospitals still aren't compliant with price transparency rules
21:17 Hospital operating margins fall to 1.4% amid outpatient slowdowns
22:10 The mental-health gap widens between employed and independent physicians
23:19 70% of Gen Z healthcare workers say they'll quit within a year
25:28 Viper: a gene-editing system that may predate — and outperform — CRISPR
27:08 Sickle cell's cure and the case that healthcare's old model is approaching deprecation
31:14 GSK commits up to $750M for Chimeric Biosciences' multiple myeloma drug
32:21 SEC rolls out a 5-year innovation exemption for tokenized securities
34:30 Why the Senate's Clarity Act failed
36:16 Circle launches ARC, a stablecoin blockchain, with BlackRock and Visa
38:54 OpenAI discloses six new AI safety incidents tied to its Astra models
39:50 Astra's misalignment problem — and why Jensen Huang calling it AGI is unsettling
41:54 "Get control of your own models" — the case for AI product liability
43:08 Talking to family about AI risk, and the UL/electricity analogy for AI safety
53:21 Staying patient and clear with people who fear AI amid election-season hype
56:00 Jensen Huang as master communicator — and why the labs need better spokespeople
58:06 OpenAI eyes a $1.2 trillion valuation ahead of a potential IPO
1:01:11 "Who's going to buy this?" — OpenAI's valuation vs. its business model and moat
1:02:16 Open-source models close the gap and erode the frontier labs' moat
1:06:21 AI as a co-scientist: Stanford researchers accelerate drug discovery
1:08:19 Turning the corner — from chronicling healthcare's decline to its ascent
1:08:43 What comes next: allocating a 10,000x increase in care capacity
#FederalReserve #Inflation #JobsReport #Housing #VentureCapital #Biotech #CMS #PriceTransparency #HospitalMargins #PhysicianBurnout #GeneEditing #CRISPR #Oncology #Web3 #StablecoinPayments #SEC #AI #OpenAI #AISafety #DrugDiscovery #HealthcarePolicy
Health:Further — September 10, 2026
In this episode, we explore sticky inflation and the widening cost-of-living gap, a wave of nine-figure biotech rounds, mounting political pressure on AI labs, the hollowing out of hospital service lines, and a Robinhood-chain experiment that turns everyday spending into equity ownership — with insights into market trends, policy changes, and technological innovations shaping the future of health and money.
Key Topics
Chapters
Hashtags
#Inflation #FederalReserve #HealthcarePolicy #ACA #Medicare #Maternity #AI #OpenAI #Anthropic #China #Biotech #Web3 #Tokenization #HealthTech #Pharma
In this episode, we explore the latest developments in economics, healthcare, AI, and Web3, providing insights into market trends, policy changes, and technological innovations shaping the future.
Key Topics
Chapters
Vic and Marcus discuss revised jobless claims, Nvidia's continued AI-driven growth, and major developments across healthcare, technology, and policy. They cover Cityblock's acquisition of Homeward Health, new telehealth prescribing rules, Meta's $17.1 billion settlement over teen social media protections, and Medicare overbilling allegations involving Humana-owned Villages Health. The episode also examines cyberattacks affecting medical device companies, a new FDA-approved treatment for pancreatic cancer, Alzheimer's blood testing, diabetes monitoring technology, and concerns about AI transparency in healthcare. They close with Nvidia's reported move to acquire Hugging Face, Stripe's OpenRouter acquisition, and warnings from major technology companies about the growing threat of AI-enabled cyberattacks.
Story Lineup
1 — In This Economy
2:32 - Story 1: U.S. Jobless Claims Fall to 203,000; Labor Market Stays Resilient [WSJ]
4:45 - Story 2: Nvidia Reports Record $96.2B Revenue, Projects 70% Growth; AI Spending Boom Intact [WSJ]
7:11 - Story 3: Fed Chair Warsh Faces Pressure at Jackson Hole; Treasury-Fed Boundary Tensions Rise [WSJ]
2 — VC Deal Review
11:15 - Story 1: Cityblock Health Secures $116M Series E, Acquires Homeward Health to Expand Rural Medicare Advantage [MedCity News]
12:24 - Story 2: Onos Health Raises $17M Series A for AI-Driven Behavioral Health Platform [MedCity News]
3 — Policy
13:09 - Story 1: DEA Sends Final Telehealth Prescribing Rule to White House for Review; Would Enable Controlled-Substance Prescribing via Telehealth [Becker's]
14:29 - Story 2 : Meta to Pay up to $17.1 Billion
4 — Health Payors
18:17 - Story 1: Humana's Villages Health Settles Medicare Advantage Billing Fraud for $541.5M Over Fake Diagnosis Codes [Healthcare Dive]
5 — Health Systems
19:43 - Story 1: UPMC Swings to $18.3M Operating Loss in Q2; Insurance Revenue Up, Patient Revenue Flat Signals Margin Pressure [Becker's]
20:27 - Story 2: Boston Scientific Operations Disrupted by Cyberattack; Ordering and Shipping Systems Hit [Healthcare Dive]
6 — Pharma & Novel Therapies
25:26 - Story 1: FDA Approves Daraxonrasib (Rasonque), First RAS Inhibitor for Advanced Pancreatic Cancer—Landmark Breakthrough [WSJ]
26:48 - Story 2: Roche and Eli Lilly Win FDA Clearance for First-of-Its-Kind Alzheimer's Biomarker Blood Test [WSJ]
28:09 - Story 3: Novo Nordisk Shares Fall as Eli Lilly Outcompetes GLP-1 Market; Stock Down 70% from June 2024 Peak [WSJ]
7 — About Health & Us / The Clinician's Voice
30:05 - Story 1: FDA Clears Abbott's First-of-Its-Kind Wearable Ketone Sensor to Detect Diabetic Ketoacidosis Risk [Fierce Biotech]
31:07 - Story 2: Nearly Half of Americans Unaware Whether AI Has Been Used in Their Care, Pew Survey Finds [Healthcare Dive]
37:32 - Story 3: Oura Health Wearable Ring Faces Class-Action Lawsuit Over Sleep-Tracking AI Accuracy Claims [MedCity News]
8 — The AI Tracker
40:10 - Story 1: Nvidia Reportedly Acquiring Hugging Face AI Model Hub for ~$13B; Control Over Open-Source Infrastructure Consolidates [Gizmodo]
41:58 - Story 2 : Stripe Buys A.I Start-Up Open Router
48:41 - Story 3: OpenAI, Microsoft, 100+ Firms Sound Alarm on Imminent AI-Enabled Cyberattack Wave Targeting Hospitals [NYT]
Vic and guest host Paul Kappleman discuss the state of U.S. healthcare under the Trump administration, including access, affordability, hospital closures, consolidation, and the potential rise of Medicare for All. They examine weakening retail sales, interest rates, $40 trillion in U.S. debt, healthcare venture capital, at-home sleep apnea diagnosis, pancreatic cancer screening, primary care, FDA leadership and AI-enabled medical devices, Medicaid asset limits, Costco entering Medicare, Providence Health Plan's exit, and Moderna's personalized cancer vaccine. They also cover an exercise pill, patient access to test results, Bitcoin and the CLARITY Act, robotic blood draws, Epic's AI platform, OpenAI's new protections for teens and enterprise users, and Amazon's expansion of drone delivery.
1 — In This Economy
17:09 - U.S. Retail Sales Fell 0.6% in July to $763.6 Billion, Missing Forecasts for Growth WSJ
17:26 - Fed Minutes Reveal Broader Support for Rate Increases WSJ
17:56 - U.S. Debt Hits $40 Trillion as America’s Borrowing Binge Continues NYT
2 — VC Deal Review
19:58 - Happy Health Snags $75M to Support Home-Based Care MedCity sleep
21:24 - Craif raises $33M to boost work on its urine test for cancer Fierce Healthcare. Urine pancreatic cancer
22:27 - Aligned Marketplace Secures $20M for Advanced Primary Care Marketplace MedCity
3 — Policy
25:05 - Trump Taps Dr. Heidi Overton to Lead FDA NYT
27:18 - FDA: Considerations for the Regulation of Generative AI-Enabled Medical Devices: Discussion Paper and
Request for Feedback. Reg.gov
4 — Health Payors
29:25 - Medi-Cal plans brace for ‘devastating’ asset limit crunch Beckers
31:35 - Costco Sells Vacations, Gas and, Soon, Medicare Plans WSJ
33:33 - Providence Health Plan to close completely after Medicare Advantage deal falls through Healthcare Dive
5 — Pharma & Novel Therapies
37:11 - Moderna Shares More Than Double on Success of mRNA Cancer Vaccine WSJ
39:50 - An ‘Exercise Pill’ Just Cleared Its First Human Test Gizmodo
6 — About Health & Us / The Clinician's Voice
41:44 - Nearly 7 in 10 patients view test results before a clinician weighs in: Study Beckers
7 — Web3
45:16 - Bitcoin hits $69,000, ether jumps 10% as Treasury buybacks, SEC crypto proposal fuel market rally The Block
45:51 - Trump pushes Congress to move on Clarity Act during White House crypto event Coindesk
8 — The AI Tracker
48:05 - FDA authorizes 1st-of-its-kind blood draw robot Beckers
Video
50:39 - Epic expands AI ambitions with agent platform, Cosmos-powered predictions and workflow automation Fierce Healthcare
54:29 - What Parents Need to Know About OpenAI’s New ChatGPT for Teens WSJ
55:38 - OpenAI’s Latest Bid to Fight Anthropic: A Promise Not to Keep Customer Data WSJ
58:06 - Amazon to Expand Drone Delivery Service to Nearly 500 Locales WSJ
From the publisher's feed
Every week, healthcare VCs and Jumpstart Health Investors co-founders Vic Gatto and Marcus Whitney review and unpack the happenings in US Healthcare, finance, technology and policy. With a firm…

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