Across decades of public life — as First Lady, Senator, Secretary of State, and presidential candidate — Hillary Rodham Clinton has become one of the most consequential American leaders of our time.

She sits down with The New Yorker's David Remnick for a candid, live conversation — a taping of The New Yorker Radio Hour — about the state of American life as the nation approaches its 250th anniversary, and the extraordinary political moment we find ourselves in: the pressures testing democratic institutions at home; mounting instability abroad in the Middle East, Asia, and Ukraine; and the uneasy intersection of leadership, power, media, and public trust.

Working to improve the lives of all Americans, Clinton is an icon for women and girls the world over. And in a changing world, her perspective on the possibilities of American life — and the threats we face both at home and abroad — is indispensable. In her recent memoir, Something Lost, Something Gained, she reflects on the challenges and dangers of a polarized nation and the reshaping of domestic and foreign policy — offering a blueprint for what each of us can do to strengthen our bonds with one another and fight for our democracy.

Expect an evening of candor, insight, and extraordinary perspective — a conversation not only about American politics at 250, but about the character of the country itself, and the choices that shape our future.