Some of the most successful cardiothoracic surgeons credit mentors for part of their achievements. Whether you are still in training, an early careerist, or a senior surgeon, taking part in a productive mentor/mentee arrangement has long-term benefits. But how do you identify a good mentor or mentee and cultivate that relationship? Drs. Mara B. Antonoff, Vinod H. Thourani, John D. Mitchell, and Elizabeth A. David describe the qualities to look for in a mentor, the importance of communication, setting realistic expectations, avoiding “mentor malpractice,” and why mentees should under promise and over deliver.