Sign up to save your podcasts
Or
Share “I’m a bit skeptical of AlphaFold 3” by Oleg Trott
Share to email
Share to Facebook
Share to X
Share to email
Share to Facebook
Share to X
Or
“I’m a bit skeptical of AlphaFold 3” by Oleg Trott
This is a link post.
So this happened: DeepMind (with 48 authors, including a new member of the British nobility) decided to compete with me. Or rather, with some of my work from 10+ years ago.
Apparently, AlphaFold 3 can now predict how a given drug-like molecule will bind to its target protein. And it does so better than AutoDock Vina (the most cited molecular docking program, which I built at Scripps Research).
On top of this, it doesn’t even need a 3D structure of the target. It predicts it too!
But I’m a bit skeptical. I’ll try to explain why...
---
First published:
June 25th, 2024
Source:
https://www.lesswrong.com/posts/D9yYmL6KPq7dcNSKE/i-m-a-bit-skeptical-of-alphafold-3
---
Narrated by TYPE III AUDIO.
View all episodes
By LessWrongThis is a link post.
So this happened: DeepMind (with 48 authors, including a new member of the British nobility) decided to compete with me. Or rather, with some of my work from 10+ years ago.
Apparently, AlphaFold 3 can now predict how a given drug-like molecule will bind to its target protein. And it does so better than AutoDock Vina (the most cited molecular docking program, which I built at Scripps Research).
On top of this, it doesn’t even need a 3D structure of the target. It predicts it too!
But I’m a bit skeptical. I’ll try to explain why...
---
First published:
June 25th, 2024
Source:
https://www.lesswrong.com/posts/D9yYmL6KPq7dcNSKE/i-m-a-bit-skeptical-of-alphafold-3
---
Narrated by TYPE III AUDIO.
More shows like LessWrong (30+ Karma)
View all
Making Sense with Sam Harris
26,434 Listeners
Conversations with Tyler
2,388 Listeners
The Peter Attia Drive
7,906 Listeners
Sean Carroll's Mindscape: Science, Society, Philosophy, Culture, Arts, and Ideas
4,133 Listeners
ManifoldOne
87 Listeners
Your Undivided Attention
1,462 Listeners
All-In with Chamath, Jason, Sacks & Friedberg
9,095 Listeners
Machine Learning Street Talk (MLST)
87 Listeners
Dwarkesh Podcast
389 Listeners
Hard Fork
5,429 Listeners
The Ezra Klein Show
15,174 Listeners
Moonshots with Peter Diamandis
474 Listeners
No Priors: Artificial Intelligence | Technology | Startups
121 Listeners
Latent Space: The AI Engineer Podcast
75 Listeners
BG2Pod with Brad Gerstner and Bill Gurley
459 Listeners