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“I’m a bit skeptical of AlphaFold 3” by Oleg Trott
This is a link post.
So this happened: DeepMind (with 48 authors, including a new member of the British nobility) decided to compete with me. Or rather, with some of my work from 10+ years ago.
Apparently, AlphaFold 3 can now predict how a given drug-like molecule will bind to its target protein. And it does so better than AutoDock Vina (the most cited molecular docking program, which I built at Scripps Research).
On top of this, it doesn’t even need a 3D structure of the target. It predicts it too!
But I’m a bit skeptical. I’ll try to explain why...
---
First published:
June 25th, 2024
Source:
https://www.lesswrong.com/posts/D9yYmL6KPq7dcNSKE/i-m-a-bit-skeptical-of-alphafold-3
---
Narrated by TYPE III AUDIO.
View all episodes
By LessWrongThis is a link post.
So this happened: DeepMind (with 48 authors, including a new member of the British nobility) decided to compete with me. Or rather, with some of my work from 10+ years ago.
Apparently, AlphaFold 3 can now predict how a given drug-like molecule will bind to its target protein. And it does so better than AutoDock Vina (the most cited molecular docking program, which I built at Scripps Research).
On top of this, it doesn’t even need a 3D structure of the target. It predicts it too!
But I’m a bit skeptical. I’ll try to explain why...
---
First published:
June 25th, 2024
Source:
https://www.lesswrong.com/posts/D9yYmL6KPq7dcNSKE/i-m-a-bit-skeptical-of-alphafold-3
---
Narrated by TYPE III AUDIO.
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