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Practical Radiation Oncology section editor, Minsun Kim, Ph.D. of University of Washington, hosts a conversation on automated treatment planning to improve plan quality beyond human intuition. A senior author on the paper published in PRO: "Clinical acceptability of automated radiation treatment planning for head and neck cancer using the radiation planning assistant", Beth Beedle, MD, of Stanford University and the chair of the AAPM TG 308: "Clinical implementation of data-driven quality control and automated treatment planning", of University of California, San Diego, Kevin Moore, Ph.D. discuss the current status and recommendations for automated treatment planning approaches to ensure patient safety.