Hippies, the Beatles, flower power, magic mushrooms, raves and festivals – that’s what most of us associate with psychedelics. But there is mounting evidence that these drugs could also be used medicinally, particularly to treat mental illnesses such as depression.

In this episode, we speak to Prof David Nutt, a psychopharmacologist who has spent decades researching how drugs affect the brain. Now a professor at Imperial College London, David has published more than 500 research papers, eight government reports, and 40 books – including one called Psychedelics, in 2023.

In this conversation, he explains how psychedelics affect the brain, how they alter people’s sense of self and perception of reality, and why they could revolutionise the future of mental health treatments.

Please note that psychedelics are Class A drugs according to UK law. Anyone caught in possession of such substances can face up to seven years in prison, an unlimited fine, or both. Information and support for those affected by substance abuse can be found at bbc.co.uk/actionline.

The following conversation specifically concerns psychedelics when used in a clinical context, given at low doses and under medical supervision. Please don’t try this at home.

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What will we all be eating in 2050? How will it be produced? And how can our diets keep us healthier for longer? If these are questions you'd like answered, why not check out the upcoming Future of Food mini-series.

You'll discover how cutting-edge farming technology is helping us to produce food that's kinder to the environment, how overlooked foods such as algae and seaweed may soon become a common sight on our plates, and how new discoveries are uncovering the fascinating science of how our bodies all respond differently to the food we eat.

Tune in to the weekly four-part miniseries, starting Monday 3rd November.

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The commonly held story goes that we all begin life as a single cell in our mother’s womb and go on from there to develop into fully formed adult human beings composed of cells of our own creation. However, recent research is showing that this isn’t quite the full picture. Not all of the cells in our bodies come from this single starting point. We are, in fact, all host to cells that have migrated from the bodies of other people – our mothers, grandmothers, siblings and even, in some cases, complete strangers.

In this episode, we’re joined by science writer Lise Barnéoud to talk about her latest book Hidden Guests - Migrating Cells and How the New Science of Microchimerism Is Redefining Human Identity.

She tells us how mothers and babies share cells across the placenta during pregnancy, how these cells make their homes within our organs and persist for our entire lives, and how this mysterious process led to a woman giving birth to the genetic children of her unborn twin sister.

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Thanks to hundreds of years of scientific progress we now know, that like every other living thing on Earth, human beings are simply assemblages of atoms and molecules that evolved over eons through a series of complex, iterative processes. But somewhere along this long and meandering journey we developed consciousness – the deep sense of self-awareness that allows us to think, feel and even allows us to attempt to understand what’s going on in the Universe around us.

In this episode, we’re joined by neuroscientist and author Dr Nikolay Kukushkin to talk about his latest book, One Hand Clapping – Unravelling the Mystery of the Human Mind.

He tells us how this entire process all started millions of years ago through the interactions of atoms such as carbon and oxygen, how taking a bottom-up approach to the development of consciousness can help to explain how human beings became such complicated entities and how the advent of artificial intelligence may, or may not, influence the future evolution of our species.

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Stars feel like a fundamental feature of the Universe – as essential as planets, galaxies and space itself. But since we know the Universe had a beginning (the Big Bang), there must also have been a first star. Before it, there was only darkness; after it, the cosmos as we know it began to take shape.

Exactly what those first stars were like – and how they transformed everything that followed – remains one of astronomy’s great mysteries. It’s a mystery that astrophysicist Dr Emma Chapman has dedicated much of her career to solving.

In this episode, Emma joins us to talk about her book First Light: Switching on the Stars at the Dawn of Time, recently updated to include discoveries from groundbreaking telescopes like the James Webb Space Telescope.

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Humanity is beautifully diverse. Some of that diversity is visible, but hidden beneath the surface, there is also a hidden web of genetic variation that collectively tells a story about how people have adapted to their environments, sometimes in weird and wonderful ways.

In this episode, we speak to Prof. Herman Pontzer, an evolutionary anthropologist at Duke University, USA, and the author of Burn: the misunderstood science of metabolism, as well as his newest book, Adaptable: the surprising science of human diversity, which inspired this conversation.

Herman tells us about how our genes can evolve over generations, how specific groups of humans have adapted to survive and thrive in different environments, and why understanding the science of diversity is so important for society as a whole.

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Chances are that when most of us think about the notion of crime our minds turn to acts committed against an individual – be it theft, fraud or even physical assault. But every day ecological crimes are committed against the planet we all live on that often fly under the radar despite the significant, far-reaching effects they have on all of us.

In this episode, we’re joined by criminal psychologist and bestselling author, Dr Julia Shaw to talk about her latest book, Green Crime – Inside the Minds of the People Destroying the Planet, and How to Stop Them.

She breaks down the factors that drive individuals and organisations to commit acts that are damaging to the environment and explains how understanding the psychology that underpins these acts can help us to keep our planet healthy for generations to come.

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Be it a cold, drafty room in a creaky old country house or a still, quiet forest on a dark night, chances are that at one point or another we’ll all have entered an environment that for some reason made us feel uneasy. But what exactly makes a certain place or situation feel so creepy, and why do we get these feelings in the first place?

In this episode, we’re joined by psychologist and magician Prof Richard Wiseman to talk about his work as a scientist who investigates the psychology behind paranormal phenomena.

He tells us how ghostly experiences may actually have evolved to help keep us away from dangerous environments, how our brains are primed to see faces that aren’t really there, and how the state of consciousness that exists between waking and sleeping can lead us to feel the presence of threatening entities lurking in our bedrooms.

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Chances are when we’re treated with medicines in hospital or pick up our prescriptions at the pharmacy, we don’t give much thought about how the drugs that are so vital for our health and wellbeing came to be. The fact is the journey that a new medicine takes from its beginnings in the laboratory to finally being administered to patients can be long and arduous. It typically takes the work of countless scientists, researchers and technologists toiling away behind the scenes for decades and is often fraught with failure. So exactly how does a new drug make the grade?

In this episode, we’re joined by oncologist and drug researcher Dr William Pao to talk about his latest book, Breakthrough – The Quest for Life-Changing Medicines.

He tells us how fundamental academic scientific lays down the bedrock for the development of a new drug, runs us through the vital importance that clinical trials play in the whole drug development process, and tells us the fascinating story of how the common everyday drug paracetamol was discovered by accident.

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Is our planet under threat from the depths of space? In this episode, we talk to solar physicist Dr Ryan French. Normally, Ryan is busy unravelling the mysteries of our Sun, but today we’ll be delving into a slightly darker topic – the many risks posed to our delicate planet from space. In his recent book, "Space Hazards: Asteroids, solar flares and cosmic threats”, Ryan covers all the many dangers our planet faces from space rocks, the Sun and the farthest reaches of the Universe. We run through some of the most pressing threats and find out just how worried we should be.

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