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Could an AI physicist soon out-innovate Einstein? 

In this exciting interdisciplinary exploration, UC San Diego’s Rose Yu dismantles the romantic myth of genius-driven science and instead offers a thrilling look at how AI could become not just a computational tool, but a genuine partner in discovery. Rose draws from her pioneering work in traffic forecasting, pandemic modeling, and high-energy physics to show how machine learning is evolving and what it can offer to the scientific community.

She walks us through the fascinating ways AI is already helping us rethink what’s possible in science: from generating novel hypotheses to rediscovering fundamental symmetries, and even beating traditional simulations in both speed and precision. With her characteristic clarity, Rose explains how she’s built data-driven surrogates for complex phenomena like the spread of epidemics and the turbulence of fluids. We also tackle some of the more existential questions: Can an AI ever experience “happy thoughts”? How close are we to AGI? And should we be worried about AI replacing us? 

If science is humanity’s greatest invention, this episode is a fascinating look at its future.

—

Key Takeaways: 

00:00 Intro 

01:04 Can an AI physicist out-innovate Einstein? 

02:07 Why are GPUs so good for AI?

12:24 Traffic modeling and AI

16:08 Is AI just imitating physics?

24:53 Epidemiology modeling and AI 

30:49 Should we be worried about AGI?

34:32 The benefits and dangers of AI

39:53 AI scientists and scientific productivity 

42:19 The impact of AI on academia and education 

52:34 Outro 

—

Additional resources: 

💻 Rose Yu’s website: https://roseyu.com/ 

—

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David Deutsch just exposed something shocking about modern science. Most quantum theories aren't actually science at all. They're just miracles disguised as explanations. When you ask how quantum entanglement works, most interpretations by popular scientists basically reduce to "magic happens." That's not science, that's giving up on our understanding of reality.

David Deutsch is a quantum physicist at Oxford, a pioneer in quantum computing, and one of the most important theoretical physicists alive. He argues that only the many-worlds theory actually explains what's happening in quantum experiments instead of just accepting it as a mystery never to be explained. This conversation reveals why modern physics has abandoned its core mission.

Key Takeaways:

00:02:15 – David Deutsch introduces the idea that infinity is not just a mathematical abstraction but a physical reality.

00:06:42 – He emphasizes that understanding infinity is central to progress in both science and philosophy.

00:11:03 – Discussion on how infinity challenges human intuition and traditional explanations.

00:18:29 – Deutsch argues that good explanations must account for infinity, not avoid it.

00:23:51 – He contrasts finite vs. infinite models of the universe.

00:30:14 – Infinity as an unavoidable aspect of quantum mechanics and the multiverse.

00:37:40 – Practical implications: infinity changes how we view knowledge, discovery, and human progress.

00:45:22 – He warns against simplistic or “bad” explanations that ignore infinite possibilities.

00:53:09 – Closing: infinity should be embraced as part of reality, not feared or reduced.

-

Additional resources:

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Sir Roger Penrose: https://youtu.be/AMuqyAvX7Wo

Sabine Hossenfelder: https://youtu.be/g00ilS6tBvs

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—

Arthur Brooks has just done the unthinkable. He’s shattered one of the most enduring myths in both science and society with the precision of a physicist and the insight of a seasoned psychologist. 

We’re talking about the belief that our minds peak in our thirties and only decline from there. Well, it turns out this belief isn’t rooted in physics but in flawed psychology. Worse, this myth is holding us back as a species. In this insightful and personal episode, Arthur explains that cognitive decline is not inevitable and that our best, most meaningful work might still be ahead—if we adjust accordingly.

Arthur himself is no stranger to reinvention. From performing with the Barcelona Symphony to leading one of Washington's most influential think tanks, and now teaching at Harvard, he’s experienced multiple intellectual lifetimes. Today, he studies happiness—not as a vague ideal, but as a measurable, achievable, and deeply human pursuit.

Together, we explore why high achievers often feel more depressed after reaching their biggest goals and why lasting fulfillment requires something different altogether. Arthur shares research on emotional temperaments, the science of fluid vs. crystallized intelligence, and the dangers of fame, power, and success. He also gives us a behind-the-scenes look at his collaboration with the Dalai Lama, and why AI might be a surprising ally in extending our cognitive abilities as we age.

—

Key Takeaways: 

00:00:00 Intro 

00:02:31 Arthur’s pivotal career change(s)

00:05:22 Failure CV and resistance to disillusionment 

00:08:36 The entropy of happiness 

00:11:57 Judging a book by its cover

00:18:04 Crystallized vs. fluid intelligence 

00:28:48 Will AI replace or amplify aging minds? 

00:31:41 Modernizing academia

00:42:40 Balancing professional and personal life

00:47:05 The hierarchy of idolatry 

00:58:33 Rapid fire questions

—

Additional resources: 

📚 The Happiness Files by Arthur Brooks: https://a.co/d/7548rbL 

—

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What if the most successful theory in science… doesn't actually explain anything?

In this episode of Into the Impossible, I talk with physicist and author Adam Becker, who wrote What Is Real?, a stunning exploration of quantum mechanics, its messy philosophical roots, and the long-ignored questions about what the theory really says about reality.

We dig deep into a paradox at the heart of modern physics: quantum mechanics works better than any theory we’ve ever invented, yet no one agrees on what it means. Becker walks us through the forgotten history of physicists like Einstein and David Bohm, who dared to question the mainstream “shut up and calculate” mindset, and explains why that mindset might be holding science back.

We explore the eerie predictions of the Many Worlds Interpretation, the mind-bending implications of Bell’s Theorem, and how modern experiments—some Nobel Prize-winning—are forcing physicists to confront uncomfortable truths about locality, realism, and the nature of observation.

If you’ve ever wondered whether quantum physics is just math, or if it really describes the world we live in, this conversation will challenge everything you thought you knew.

—

Key Takeaways: 

00:00 Intro

02:01 Interpretations of quantum mechanics 

05:04 Einstein’s discontent with quantum mechanics

08:01 EPR paradox

10:16 Many-worlds interpretation and Everettian mechanics 

17:37 John Bell and Bell’s theorem 

23:43 Experimental tests of quantum mechanics  

27:21 Quantum computing and its promises

29:17 What is real? 

31:56 Outro

—

Additional resources: 

➡️ Learn more about Adam:

💻 Website: https://freelanceastrophysicist.com/ 

📚 What Is Real? By Adam Becker: https://a.co/d/5xxMYTj

—

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Does free will exist? It's a question that's haunted philosophers for centuries. But physicist Sabine Hossenfelder has a provocative answer that might just disturb you. She says free will doesn't

Everything is determined by the laws of physics. But here's the paradox that's fascinated me. I've talked to Sam Harris, Dan Dennett, Robert Sapolsky, all brilliant minds who agree that free will is an illusion. Yet, when I asked them if they've ever encountered someone who acts like they don't have free will, they all said no. So how can this be?

How can we all be determined by physics, yet live as if we're making genuine choices? This isn't some abstract philosophical exercise, no. Sabine's insight has real implications for artificial intelligence, quantum computing, and the future of consciousness itself.

She explains why AI may already have the same kind of agency that we do, and why quantum computers could reveal that we fundamentally misunderstand the nature of reality.

Key Takeaways:

-----------------------------------------------------------------------------------------

Additional resources:

Check out Sabine’s channel: https://www.youtube.com/@SabineHossenfelder

-----------------------------------------------------------------------------------------

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Sir Roger Penrose: https://youtu.be/AMuqyAvX7Wo

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Avi Loeb: https://youtu.be/N9lUceHsLRw

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Why aren't whales building rockets? They have bigger brains than we do after all. In this episode with Stephen Wolfram, we talk about why more brainpower doesn't always mean more understanding, and how neural architecture faces physical constraints.

Stephen Wolfram says even super intelligent AIs may hit hard computational limits. In our conversation today, we explore why intelligence has a ceiling, and how ideas like Wolfram's Ruliad, computational irreducibility and brain size scaling reveal the boundaries of thought itself.

Wolfram created Mathematica, Wolfram Alpha, it's probably in your pocket right now, in your cell phone, and he's now building a radical new theory of everything grounded in computational reality.

If he's right, smarter doesn't always mean deeper. It might just mean we get stuck.

Key Takeaways:

00:00 – 01:34 Are we discovering or simulating the universe?

01:34 – 06:50 Ruliad defines reality

06:50 – 10:02 Brains compress data into decisions, experience.

10:02 – 17:00 Math models nature, not necessarily its foundation.

17:00 – 25:07 AI may trap us like algebra did.

25:07 – 29:42 LLMs mimic minds, but lack depth.

29:42 – 35:57 Shared minds define reality; Boltzmann brains questioned.

35:57 – 42:28 Free will arises from irreducibility.

42:28 – 47:04 AIs may inherit computational free will.

47:04 – 52:45 Exploring Ruliad = expanding intellectual paradigms.

52:45 – 59:06 Massless particles = timeless, universal concepts?

59:06 – 01:07:32 Immortality blocked by biological irreducibility.

01:07:32 – End Biggest question: extend life or decode reality?

-------------------------------------------

Additional resources:

The Second Law: Resolving the Mystery of the Second Law of Thermodynamics: https://www.amazon.com/Second-Law-Resolving-Mystery-Thermodynamics/dp/1579550835

https://www.wolframalpha.com/

-------------------------------------------

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In this captivating conversation, we dive deep into the cosmos with renowned cosmologist, podcaster, and UC San Diego professor Dr. Brian Keating. Joined by Mike Misha and Xinghui, Brian takes us on a journey from the childhood wonder inspired by the Moon to the high-altitude peaks of Chile and the frigid expanse of the South Pole, where he's helped pioneer the development of cutting-edge telescopes aimed at unlocking the secrets of the universe.

This episode is from the 632nm Podcast

-

Takeaways:

00:00 Moon Fascination and Antarctic Astronomy

09:38 "Proof of Earth's Orbit via Parallax"

14:36 Uncharted Light Polarization Exploration

19:45 Challenges in Measuring Polarization

23:41 "Transistor Tech for Microwave Signals"

26:52 Optimal Telescope Size for Science

31:13 Collaborative Scientific Learning Journey

37:20 "Steady State vs. Big Bang"

46:43 Universe's Earliest Light Revealed

51:25 Rapid Advances in Observational Technology

58:01 Motel Suicide and Leadership Shift

58:50 Near-Miss: Nobel Prize Revelation

01:04:13 Missed Signals, Planck Pressure

01:13:54 Detecting Cosmic Phenomena with Telescopes

01:18:42 Balanced Research in Cosmology

01:23:27 Space Telescope Vision Expansion

01:26:51 AI's Limits in Predicting Relativity

01:31:28 Reevaluating the Nobel Prize Criteria

01:38:20 Musk's Mars Vision: Science Disruption

01:41:46 Balancing Science and Personal Life

-

Watch the episode on other platforms:

YouTube: https://www.youtube.com/watch?v=5z3THHIQorc&list=PL87anKnyrxSINa7feABRBcXA_fIQzqPH0

Apple Podcasts: https://podcasts.apple.com/us/podcast/how-we-build-telescopes-to-explore-the-early-cosmos/id1751170269?i=1000719643327

Spotify: https://open.spotify.com/episode/60hbFQNpmBJvDsdHM5WgDW?si=e91b6fbc60a5411d

Twitter: https://x.com/632nmPodcast/status/1950231216143126552

Substack: https://open.substack.com/pub/632nmpodcast/p/listening-to-the-echoes-of-the-big?r=409hsq&utm_campaign=post&utm_medium=web&showWelcomeOnShare=true

-------------------------------------------------------------------

Join this channel to get access to perks like monthly Office Hours:

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Think Like a Nobel Prize Winner, with life changing interviews with 9 Nobel Prizewinners: https://a.co/d/03ezQFu

My tell-all cosmic memoir Losing the Nobel Prize: http://amzn.to/2sa5UpA

The first-ever audiobook from Galileo: Dialogue Concerning the Two Chief World Systems: Ptolemaic and Copernican https://a.co/d/iZPi9Un

📺 Watch my most popular videos:📺

Neil Turok https://www.youtube.com/watch?v=Dt5cFLN65fI

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Eric Weinstein vs. Stephen Wolfram https://www.youtube.com/watch?v=OI0AZ4Y4Ip4?sub_confirmation=1

Sir Roger Penrose: https://youtu.be/AMuqyAvX7Wo

Sabine Hossenfelder: https://youtu.be/g00ilS6tBvs

Avi Loeb: https://youtu.be/N9lUceHsLRw

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In a sweeping conversation sparked by his new book The War on Science, Lawrence Krauss charts how well-intentioned campus DEI bureaucracies, politicized funding mandates, and “language-as-violence” taboos are eroding the core scientific virtues of open inquiry and empirical scepticism, while drawing historical parallels from Lysenkoism to today’s hiring rubrics and challenging listeners to defend freedom of thought with the same passion they reserve for social justice. He then pivots from diagnosis to remedy, outlining a five-point rescue plan—slashing ideological litmus tests, restoring merit-based evaluation, insulating grant agencies from mission creep, teaching students to steel-man opposing views, and benchmarking success against China’s unencumbered research surge—arguing that only by re-centering evidence over ideology can science remain humanity’s most reliable truth-seeking enterprise.

—

Key Takeaways: 

—

Additional resources: 

📚 The War On Science by Lawrence Krauss: https://a.co/d/6ntEbll 

—

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Is the universe fine-tuned for life, or is it just a lucky accident?  Could the multiverse explain why our universe is so perfectly suited for life? And how much can the fundamental constants change before life becomes impossible? 

Today, I’m joined by Fred Adams, a theoretical physicist from the University of Michigan. Fred works in the general area of theoretical astrophysics with a focus on the study of star formation and cosmology. He is internationally recognized for his work on the radiative signature of the star formation process, the dynamics of circumstellar disks, and the theory of the initial mass function for forming stars. Fred is the author of The Five Ages of the Universe and Origins of Existence, and has dedicated much of his career to understanding the structure and fate of the cosmos. 

In this episode, we break down the concepts of fine-tuning, the anthropic principle, and the multiverse. Could the universe's perfect conditions for life point to a deeper, purposeful design, or is it just a product of chance? What if there are other universes out there with completely different rules, maybe even with their own forms of life? 

Trust me, this episode is going to make you rethink everything you thought you knew about existence, so don’t miss out!

—

Key Takeaways: 

00:00 Intro 

01:29 Judging a book by its cover

02:12 DESI results and the equation of state

06:39 The cosmological constant and its role in our universe 

12:31 Fine-tuning as a tool 

32:37 The Hoyle resonance and carbon production 

39:28 Probability distribution and fundamental theory 

45:11 Intelligent design and anthropic arguments

52:30 The multiverse and its implications 

58:14 Outro 

—

Additional resources: 

Learn more about Adam:

💻 Website: ⁠https://freelanceastrophysicist.com/⁠ 

📚 More Everything Forever: ⁠https://a.co/d/ajlYHvZ⁠ 

—

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—

Into the Impossible with Brian Keating is a podcast dedicated to all those who want to explore the universe within and beyond the known.

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What if the future tech billionaires keep promising us isn’t the answer, but part of the problem?

In this episode of Into the Impossible, I talk with Adam Becker, author of More Everything Forever, about the big dreams coming out of Silicon Valley—especially when it comes to AI and the future of humanity.

We take a hard look at the idea that AI is going to fix everything, launch us into space, and solve all our problems along the way. It’s a powerful story, and a lot of very smart, very rich people believe it. But what if they’re getting the science—and the big picture—wrong? Becker argues that people like Elon Musk and Marc Andreessen are chasing a future that ignores some pretty basic realities: limits on energy, physics, and even society itself.

Instead of creating a better world, their vision might actually make things worse, deepening inequality, spreading bias, and putting even more power into the hands of a few.

If you’re excited about AI, curious about space, or just wondering where all this is heading, this is a conversation you’ll want to hear.

—

Key Takeaways: 

00:00 Intro

00:44 AI boom or AI doom? 

03:40 What are tech billionaires wrong about?

06:10 Influence of science fiction on tech billionaires 

11:05 Religious parallels in AI and space exploration  

15:37 The search for extraterrestrial intelligence 

24:16 Effective altruism and long-termism 

35:28 Optimism and skepticism about AI 

44:46 Judging a book by its cover

47:53 Impact of AI on underrepresented communities 

—

Additional resources: 

Learn more about Adam:

💻 Website: https://freelanceastrophysicist.com/ 

📚 More Everything Forever: https://a.co/d/ajlYHvZ 

—

➡️ Follow me on your fav platforms:

✖️ Twitter: https://twitter.com/DrBrianKeating 

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✍️ Check out my blog: https://briankeating.com/cosmic-musings/ 

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—

Into the Impossible with Brian Keating is a podcast dedicated to all those who want to explore the universe within and beyond the known.

Make sure to follow/subscribe so you never miss an episode!

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