Are independent research sites slowly being squeezed out of existence—or is there more opportunity than ever?

In this episode of Note to File, Brad and Denali sit down with Dan Sfera for a candid, unfiltered conversation about the real state of clinical research: consolidation, private equity, AI, site networks, and what it all means for the people actually running studies and caring for patients.

From "when does being a site owner stop being fun?" to digital twins, AI, and the death of the generalist, we dig into the tension between scale, margins, and meaning in this industry.

If you're a site owner, CRC, CRA, sponsor, or just clinical-research-curious, this one's for you.