When Charles Sexton was a boy, he was taught that his father, Eddie, was God. At first, he and his 11 brothers and sisters were Eddie's willing and loyal disciples willing to die, or to kill, to protect each other and safeguard the family secret. But as the Sexton family descended into madness and bloodshed, Charles began to have doubts, and the family secret started becoming harder and harder to keep quiet.

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Christin Kuklinski, daughter of one of America's most prolific serial killers, gives an exclusive interview. New footage reveals the sinister double life of a heartless murderer.

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John Hummel sits on death row for the savage 2009 slayings of his family, including his pregnant wife, his 5-year-old daughter and his father-in-law. Now only weeks before his execution, Hummel grants one final interview.

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Elaine Rice makes a horrific discovery after visiting her sister's Maryland home. There, she finds the bodies of her sister, her disabled nephew and the nephew's nurse. Elaine tries to make sense of the crime while police track down an appalling suspect.

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When Sherman McCrary met Carl Taylor, they quickly formed a wicked partnership. The father and son-in-law started writing bad checks together to support their families. But then checks gave way to guns and these small time criminals developed a sweet tooth for donuts and death. With their wives and children by their sides, they travel all over the country robbing grocery stores and engaging in a series of horrific rapes and murders. Nothing seems too sadistic for this clan of killers. It takes nearly two years before police are able to finally catch them and unveil one of the deadliest families in U.S. history.

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Residents in a small working-class suburb of Indianapolis knew to stay away from the Reese home. Growing up, four of the Reese children terrorized the neighborhood, but their father Paul Reese was the real evil. He was a drug user and had served time in prison for attempted murder. When a 13-year-old girl named Dawn Stuard disappears and is found strangled to death not far from the Reese home, all eyes focus on this family of criminals. Detectives believe one of them took the young girl's life, but after several months the case goes cold. It will take more than twenty years and a string of murders before the dark and deadly secret is finally revealed.

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Carl and Billy Isaacs, and half-brother Wayne Coleman, were born into a home of poverty and neglect. Without parental restrictions, the brother's ran wild and spent their formative years in and out juvenile detention. By adulthood, Carl and Wayne were convicted felons, serving time in the same prison, but the bars couldn't hold them. After escaping, the fugitives are reunited with younger brother Billy. Unrestrained and without conscience, this band of brothers cuts a bloody and violent path down the east coast in a 12-day crime spree that ends with the most brutal murders the state of Georgia has ever seen.

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Brothers Reginald and Jonathan Carr were the product of a childhood filled with toxic influences. Alcohol, violence and sexual activity were routine in their daily lives even as children. These little boys taking on big man responsibilities led to a reckless lifestyle governed by their own twisted rules. After Reginald serves time in jail, the brothers partner up and head west to Wichita in search of easy sex and money. Their crimes continue to escalate, finally culminating in a heinous night of robbery, sexual torture, and gut wrenching violence that claims several innocent lives, and is now forever known as the "Wichita Massacre."

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Brookey Lee West and her mother Christine Smith have always been at odds. At a young age, Brookey saw her mother go to jail for attempted murder leaving her alone with her Satanist father. As an adult, Brookey became a successful businesswoman, but she could never quite quit Christine. The two followed each other in and out of strange relationships and even stranger schemes. Soon, the pair moves to Vegas, and it isn't long before Christine goes missing. Brookey tells everyone she's put her mother in a nursing home, but this mother/daughter couple are more alike than anyone knows and there's only room for one.

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For the Stiles family, destiny was determined at birth. A rare birth defect called ectrodactyly has been passed down from generation to generation. However, the family has learned how to turn misfortune into profit in the strange world of the traveling carnival sideshow. Taking the spotlight on stage as the "Lobster Family", the family's trademark show draws in the crowds, but the most unsettling thing about them isn't their appearance, but what goes on after the curtain has fallen. Backstage, a dark existence of domestic violence, alcohol abuse, and shocking crimes binds this family together, before ripping them apart for good.

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