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This episode explores adjuvant medications used to enhance pain management alongside opioid agonists, providing improved pain relief and reducing opioid doses. We cover various adjuvant classes, including tricyclic antidepressants, anticonvulsants, CNS stimulants, antihistamines, glucocorticoids, bisphosphonates, and NSAIDs. Learn how these medications—originally developed for other conditions—help target pain through different mechanisms, offering a multidimensional approach to pain management. Key therapeutic uses, expected actions, complications, contraindications, and interactions of each adjuvant category are discussed to aid in comprehensive pain management.
All information in this podcast is sourced from ATI Pharmacology 2024.