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Our brains run on infrared light. Mitochondria in the brain absorb red and near-infrared light and use it to boost cognition and energy. And mitochondrial dysfunction is a hallmark of Parkinson's, Alzheimer's and depression.
John Mitrofanis has spent 20 years on the question: If infrared light restores the mitochondria, can it save the brain cells that die in Parkinson's?
John Mitrofanis is a neuroanatomist and Scientific Director of Fonds Clinatec in Grenoble, France, the research center founded by Alim-Louis Benabid, the father of deep brain stimulation. He is also an honorary Professor at University College London's Institute of Ophthalmology, and was Professor of Anatomy at the University of Sydney for over a decade. He is the author of Run in the Light: Exploring Exercise and Photobiomodulation in Parkinson's Disease.
Episode show notes + practical takeaways: https://livelongerworld.com/p/jmitrofanis
He explains:
◼️How infrared light and exercise release the same molecules in the brain, and what BDNF does.
◼️How red and near-infrared light restores mitochondrial function in cells that are dying
◼️How Parkinson’s may begin in the gut
◼️Why current Parkinson’s drugs and deep brain stimulation relieve symptoms but don’t stop the cells from dying
◼️ Red light and sleep: the glymphatic system, brain fog, and why he uses a helmet every day
◼️ Biophotons: the light your cells emit, and why stressed cells and healthy cells emit differently
TIMESTAMPS:
00:00 Cells use light to repair each other
01:00 Red light and exercise work on the same mechanism
02:50 BDNF: the molecule both exercise and light release
06:11 Blue light suppresses melatonin, red light repairs cells
09:00 The Nobel Prize won with red light, and the laser that failed to cure cancer
14:02 What deep brain stimulation actually does
14:54 Why the Parkinson's brain becomes "very, very naughty"
16:17 The beauty of deep brain stimulation, and its limit
18:40 "You apply red light on it." And I laughed
20:57 The light-treated mice kept more dopamine cells alive
23:36 Results of red light to the brain clinical trial
24:16 Is it already too late once symptoms appear?
26:48 Where he disagrees with Glen Jeffery on how deep light penetrates
28:58 Light on the body that reached the brain
31:33 Microvesicles: how cells in trouble call for help
33:12 Does Parkinson's start in the gut?
37:32 Could you skip the device and just sit in the sun?
42:06 What other Parkinson's trials are actually running
44:43 Epilepsy, autism, and cancer
45:56 The cancer evidence that cuts both ways
47:01 What's holding the trials back
48:10 Red light and sleep
49:05 We still don't know why we sleep
01:00:17 He wears the helmet every day
01:02:27 Health Stacked
01:03:15 Red light after a heart attack
01:06:41 670, 810 or 850: which wavelength and how deep
01:11:32 Why 40 hertz seems to be the magic number
01:12:03 Does the time of day matter?
01:16:00 Biophotons: the light inside us
01:22:28 Cancer cells and UV
01:30:22 Biophotons are the frontier
AASTHA, LIVE LONGER WORLD:
Join 2,400+ for practical health protocols on circadian alignment, light, EMF, and non-toxic living: https://livelongerworld.com/
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HEALTH PRODUCTS I LOVE:
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◼️Healthy Home Shop Circadian Bulbs: https://thehealthyhome.shop/livelongerworld for 10% off
Dr. John Mitrofanis:
Profile: https://profiles.ucl.ac.uk/46795-john-mitrofanis
Introducing HEALTH STACKED: https://www.healthstacked.com/
RELATED POSTS:
Boost Mitochondria with Infrared & Sunlight | Glen Jeffery: https://www.livelongerworld.com/p/gjeffery
97 Year Old Brain Scientist: This One Nutrient Prevents Dementia: https://www.livelongerworld.com/p/mcrawford
Most biology textbooks treat the water in our body as background, a solvent that DNA and proteins float around in. But what if a large portion of the energy in our body is actually coming from the water in our cells? And what if a disturbance to the structure of that water is a hallmark of cancer and other diseases?
Dr. Gerald Pollack is a Professor of Bioengineering at the University of Washington and one of the few scientists studying what water is actually doing inside our cells. He says water is not the background, it is doing the work. It is a battery, and it is supplying us energy.
Episode show notes + some bonus clips from this episode I only released for premium subscribers, find them: https://livelongerworld.com/p/gpollackHe explains:
◼️ How 99% of the molecules in our body are water molecules, and how water is not just a background solvent
◼️ How water is a battery and gives us energy
◼️ Why every cancer cell is dehydrated with low electrical potential
◼️ The role of infrared light and sunlight on water in our cells
◼️ What builds EZ water: sun, sauna, red light, grounding, juicing, deuterium depleted water, turmeric, holy basil and ghee
◼️ The effect of Hyperbaric oxygen, PEMF and magnets on EZ water
◼️ The link between dementia and EZ water
TIMESTAMPS:
00:00 Water in our cells is central to every disease
00:38 Why almost nobody in biology studies water
01:18 99% of your molecules are water. So why is it treated as filler?
03:41 What water is actually doing inside a cell
07:44 Gilbert Ling, and the book that made his students say all of biology is wrong
11:25 The experiment that started structured water research
14:09 Why cellular water behaves more like a gel than a liquid
16:29 The moment they realized water is a battery
18:29 What charges the water battery, and it isn't food
18:52 Health Stacked
19:43 Is all the water in your cells this kind of water?
23:46 Why he says we shouldn't even call it water
24:57 Does energy actually come from ATP?
27:23 If ATP isn't the fuel, what is it doing there?
30:38 What every cancer cell has in common
33:47 Free things that rebuild the structure of your cellular water
34:48 Turmeric, holy basil and ghee: what his lab found when they tested them
35:11 Morning sun, red light, saunas and grounding
36:22 Hyperbaric oxygen, and how he went looking for it
37:26 PEMF, FSM, and the magnet result that surprised him
41:42 Do WiFi routers shrink the water in your cells?
43:47 The dementia case & water connection
46:32 His answer to the strongest criticism of his work
51:13 Healers, water memory, and the paper he's about to publish
54:36 What anesthesia does to the water in your cells
55:07 What changes if he turns out to be right
57:30 One thing behind almost every disease?
59:07 Why he thinks water drives volcanoes and earthquakes
AASTHA, LIVE LONGER WORLD:
Join 2,400+ for practical health protocols on circadian alignment, light, EMF, and non-toxic living: https://livelongerworld.com/
X: https://x.com/aasthajs
Instagram: https://www.instagram.com/aasthajs/
My health stack: https://www.healthstacked.com/aasthajs
LinkedIn: https://www.linkedin.com/in/aasthajs/
HEALTH PRODUCTS I LOVE:
◼️VivaRays 4 in 1 Blue Blockers and UV transmitters: https://vivarays.com/livelongerworld or discount code LIVELONGERWORLD for 10% off
◼️Healthy Home Shop Circadian Bulbs: https://thehealthyhome.shop/livelongerworld for 10% off
◼️Daylight Computer No-blue screen: https://buy.daylightcomputer.com/livelongerworld for $25 offFull list of health products I use: https://www.healthstacked.com/aasthajs
Dr. Gerald Pollack:
Website: https://www.pollacklab.org/
Books: https://www.pollacklab.org/publications
RELATED POSTS:
Avoiding the sun kills more people than skin cancer: https://www.livelongerworld.com/p/sunsmoking
I covered my WiFi router in foil & reduced EMF radiation 50x: https://www.livelongerworld.com/p/emfphone
Why I Stopped Taking Vitamin D Supplements: https://www.livelongerworld.com/p/vitd
Oxford physiologist Denis Noble reveals why your genes are not the blueprint for life, why evolution itself works nothing like the selfish gene made us believe, and why the failed promise to cure disease by reading our DNA points to a completely different understanding of health and aging!
Denis Noble built the first working mathematical model of the heart in 1960 and is one of the founding figures of systems biology. He is a professor at Oxford with a career spent studying how living systems work, and he now argues that the genome is a database the living cell draws on, not the program running the show.
He explains:
◼️Why the Human Genome Project never delivered the cures we were promised
◼️Why your DNA cannot actually predict most disease
◼️The CD analogy: why studying genes tells you nothing about the music of life
◼️His long-running clash with Richard Dawkins and the selfish gene
◼️Why purpose and intelligence run all the way down, from your immune system to a predator hunting its prey
Episode Show Notes: https://livelongerworld.com/p/denisnoble
TIMESTAMPS:
00:00 The Selfish Gene Is Just Not Correct
00:21 What Are Functional Networks, Really?
02:09 Genes Build the Muscles, But Don't Move Them
09:42 Your Genes Are a CD, Not the CD Player
12:11 Can Your DNA Predict Your Disease?
14:23 If Not Genes, How Do We Find Cures?
18:18 Then Does Gene Therapy Even Work?
21:32 Why Scientists Can't Let the Paradigm Go
24:08 What Darwin and Lamarck Actually Said
31:42 Do Animals Choose? Darwin Thought So
38:07 The Finite Monkeys Problem With Evolution
45:15 Inheritance Without Changing Your DNA
49:31 How Do You Actually Reproduce Denis Noble?
50:49 Is the Selfish Gene Right From Evolution's View?
54:45 Answering Jerry Coyne: Isn't DNA the Recipe?
59:51 Who Wrote the Genetic Code?
1:08:22 The Problem of Form: You Can't Get It From Genes
1:12:01 The Mitochondria Accident That Made Complex Life
1:13:05 Why Big Life Needs a Heart
1:17:54 Why Mars Is a Pipe Dream
1:18:45 Mike Levin and the Alignment of the Body
1:21:29 What Does Denis Disagree With Mike Levin On
1:24:59 The Biggest Taboo: Purpose in Biology
1:27:35 Is Consciousness Just Expensive Energy?
1:28:55 What Your Immune System Knows
1:42:01 How Birds at Altitude Prove the Point
1:44:29 Final Thoughts: Life Is More Interesting Than You Think
DENIS NOBLE:
Website: https://www.denisnoble.com/
Books: https://www.denisnoble.com/buy/
AASTHA, LIVE LONGER WORLD:
Newsletter: https://livelongerworld.com/
X: https://x.com/aasthajs
Instagram: https://www.instagram.com/aasthajs/
My health stack: https://www.healthstacked.com/aasthajs
Full list of health products I use: https://www.healthstacked.com/aasthajs
CAMERON, RICCI FLOW NUTRITION:
Newsletter: https://ricciflow.substack.com/
X: https://x.com/ricciflowhealth
Instagram: https://www.instagram.com/ricciflownutrition/
PREVIOUS PODCAST WITH DENIS NOBLE & MICHAEL LEVIN on Biology's Functional Networks, NOT Genes, are key for Longevity: https://www.youtube.com/watch?v=0_Ak-1rbbWg&t=3823s
Circadian scientist Dr. Martin Moore-Ede reveals why the LED bulbs in nearly every home may be driving a rise in breast and prostate cancer, why he calls the light we now live under the tobacco of our time, and why the modern fear of the sun may be shortening our lives instead of protecting them!
Dr. Moore-Ede discovered the master circadian clock in the human brain, the suprachiasmatic nucleus, and ran a sleep and circadian research lab at Harvard Medical School for two decades. He has spent 50 years studying how light governs human health, and now argues that the shift to blue-rich LED lighting has created an environment our bodies were never built for.
He explains:
◼️ Why breast, prostate, and colorectal cancer track almost exactly with how much electric light a society uses
◼️ Why melatonin is not the sleep hormone you think it is, and what it really does at 2am
◼️ How LEDs strip out the red and infrared your mitochondria need for energy
◼️ Why the sun exposure data flips skin cancer advice on its head
◼️ Why your children are going short-sighted, and the wavelength that prevents it
◼️ Why the $200 blue-light glasses most people buy block the wrong blue
AASTHA, LIVE LONGER WORLD:
Episode Show Notes: https://livelongerworld.com/p/mmooreede
X: https://x.com/aasthajs
Instagram: https://instagram.com/aasthajs
My health stack: https://www.healthstacked.com/aasthajs
TIMESTAMPS:
00:00 LED Light Is the Tobacco of Our Time
01:33 The Connection Between Cancer and LED Lighting
04:05 Why Hormone-Driven Cancers Are Hit the Hardest
07:49 Is There a Link to Glioblastoma?
08:14 Why Melatonin Is Not the Sleep Hormone
11:40 There Is No Blue Light in Nature After Sunset
15:58 We Live in Junk Light, Just Like Junk Food
17:21 What Wavelengths Are LEDs Actually Missing?
20:44 The Infrared We Lost When We Banned Incandescents
22:52 The Two Ways LEDs Are Harming You
30:05 Health Stacked
30:56 White vs Yellow Light: Why It's the Wrong Question
33:59 Lux, Lumens, and a 100-Year-Old Mistake
38:27 What LED Light Does to Your Heart and Immune System
40:44 Why Regularity Matters as Much as the Light Itself
43:07 The Camping Study That Reset Everyone's Body Clock
49:56 Sunlight vs Skin Cancer: We Have It Backwards
53:03 The 450 vs 480 Spike Almost No One Gets Right
59:52 Why Life Evolved to Run on Blue Light
01:03:13 Melanopsin: Your Body's Blue Detector
01:08:28 Do Melatonin Supplements Actually Do Anything?01:12:19 Why the Wrong Side of a Time Zone Can Kill You
01:15:37 Is There Something Special About Dawn?
01:17:12 Light and the Early Onset of Puberty
01:20:53 The Aggressive Kid Who Changed When the Lights Did
01:21:51 Should You Replace Your Windows?
01:24:00 Do not wear sunglasses in the morning!
01:26:44 What About Daytime Lighting?
01:27:41 Do Blue-Light-Blocking Glasses Work at Night?01:31:20 Take Your Lighting Into Your Own Hands
PRODUCTS I USE FOR BETTER CIRCADIAN RHYTHM:
◼️VivaRays 4 in 1 Blue Blockers: https://vivarays.com/livelongerworld or code LIVELONGERWORLD for 10% off
◼️Healthy Home Shop Circadian Bulbs: https://thehealthyhome.shop/livelongerworld for 10% off
◼️Daylight Computer No-blue screen: https://buy.daylightcomputer.com/livelongerworld for $25 off
◼️Chroma Circadian-Aligned Desk Lamp: https://getchroma.co/photonsfromaastha and code LIVELONGERWORLD for 10% off
Full list of health products I use: https://www.healthstacked.com/aasthajs
Dr. Martin Moore-Ede:
Website: https://thelightdoctor.com/
Book: THE LIGHT DOCTOR: Using Light to Boost Health, Improve Sleep, and Live Longer: https://amzn.to/4yrwWWu
HEALTH STACKED, the trusted longevity marketplace: https://www.healthstacked.com/
RELATED POSTS:
Avoiding the sun kills more people than skin cancer: https://www.livelongerworld.com/p/sunsmoking
Your Lights are Wrecking your Sleep (Here’s What I Use): https://www.livelongerworld.com/p/redlights
Your Screens Are Keeping You Awake: 60 second fix: https://www.livelongerworld.com/p/redphone
97-Year-Old Brain Scientist Professor Michael Crawford reveals why the human brain has been physically shrinking for thousands of years, why he believes it was DHA, an omega-3 fat from the sea, and not your genes, that built human intelligence, and why the official advice to limit fish in pregnancy may be harming an entire generation of babies!
Professor Michael Crawford is Director of the Institute of Brain Chemistry and Human Nutrition and a visiting professor at Imperial College London, with more than 300 published papers and the 1972 work that first linked DHA to the evolution of the human brain. At 97, he is still sharp, still publishing, and still arguing that modern nutrition has neglected the one organ that makes us human.
He explains:
◼️ Why the brain physically cannot work without DHA, full stop
◼️ Why it was DHA, not DNA, that shaped the human brain
◼️ Why he says the FDA is wrong about limiting fish in pregnancy
◼️ How seed oils quietly crowd this fat out of your brain cells
◼️ Whether dementia and Alzheimer's actually begin in the womb
◼️ Why humans could only have evolved big brains beside the sea
◼️ How chicken and eggs lost almost all of their brain fat
◼️ Why he believes DHA works like a semiconductor in your neurons
Episode Show Notes: https://livelongerworld.com/p/mcrawford
Find me on X: https://x.com/aasthajs
Instagram: https://instagram.com/aasthajs
My health stack: https://www.healthstacked.com/aasthajs
TIMESTAMPS:
00:00 The Brain Food We Stopped Eating
00:32 "Your Brain Won't Work Without DHA. That's just full stop"
04:04 It Wasn't DNA That Made Us Human
06:50 How the Eye Built the Brain
08:00 Why Carnivores Are Sharper Than Herbivores
11:35 The Flowering Plant That Invented Pregnancy
14:22 The Placenta: An Organ Built From One Fatty Acid
15:35 Why Arachidonic Acid Is Wrongly Demonized
18:18 More Astrocytes Than Neurons: Who Really Runs the Brain
21:39 Health Stacked
22:38 DHA vs Arachidonic Acid: Two Different Origins
25:21 How the Fetus Hoards DHA and Rejects the Rest
30:31 Are Seed Oils Actually Starving Your Brain?
32:24 Why the FDA is wrong about Fish in Pregnancy
37:50 Do Fish Oil Supplements Work?
44:15 The Lack of Fish in Pregnancy is causing ADHD and Austism
50:10 Why Governments Only Care About Body Size, Not Brains
52:00 "A Race of Morons": The Warning From 1972
55:04 Does Dementia Actually Begin in the Womb?
59:16 Does the Father's Nutrition Matter Too?
59:40 The Importance of Arachidonic Acid that Infant Formula Leaves Out
01:02:24 How Often You Should Actually Eat Seafood
01:04:05 Can Vegetarians and Vegans Get Enough?
01:05:04 Can Genetics Let You Skip Seafood? The India Case
01:08:00 Why Humans Could Only Have Evolved Beside the Sea
01:11:55 Farming the Sea: What Japan Figured Out
01:17:22 The Collapse of DHA in Chicken and Eggs
01:20:52 Why Corn-Fed Everything Is Lower in DHA
01:22:32 The Semiconductor Theory of the Brain, Explained
01:27:20 What Dr. Crawford's Vision Is Like at 97 years old
01:28:39 The Rare Double-DHA Molecule in Your Retina
01:29:23 Where Dr. Crawford Lands on Saturated Fat
01:31:09 His Advice to Young Scientists: Challenge Everything
01:32:07 Closing: Why This Is a Three-Generation Emergency
AASTHA, LIVE LONGER WORLD:
Join 2,100+ for practical health protocols on circadian alignment, light, sleep, non-toxic living and more: https://livelongerworld.com/
X: https://x.com/aasthajs
Instagram: https://www.instagram.com/aasthajs/
My health stack: https://www.healthstacked.com/aasthajs
Dr. Michael Crawford:Book The Shrinking Brain: https://amzn.to/4vEJiZ3Introducing
HEALTH STACKED: https://www.healthstacked.com/
I built the health store I’ve always wanted. Health Stacked is a vetted marketplace of 500+ health and longevity products across 12 categories like sleep, fitness, non-toxic home, lighting & EMF, and more.
Products are screened for plastic, PFAS, and 20+ toxins. Inclusion is 100% merit-based. And every product has been hand-picked by me.
Is a hidden molecule in your food and water silently fueling cancer, Alzheimer's, and Parkinson's? Could the supplements you trust every day be making it worse?
Dr. Stephanie Seneff is a senior research scientist at MIT (published in PNAS, Frontiers, FASEB) with a career studying nutrition, biology, and toxicology.
In this conversation, she explains why deuterium — a heavier form of hydrogen — may be the most underrated driver of chronic disease, why cancer might be the body's repair response to deuterium-damaged mitochondria, and why most supplements may backfire.
We discuss:
◾ Why deuterium may be the most important molecule you've never heard of
◾ How glyphosate stops your body from clearing deuterium
◾ The two supplements you should stop taking immediately
◾ Why she says: "I don't believe in supplements"
◾ Why chemo may be working backwards on cancer
◾ How to make your gut produce low-deuterium water
◾ The folic-acid-in-pregnancy and autism connection
◾ Why she drinks deuterium-depleted water every day
This is Dr. Seneff's second appearance on Live Longer World. Her first episode on glyphosate is linked below.
Episode Show Notes: https://livelongerworld.com/p/sseneff2
Find me on X: https://x.com/aasthajs
My health stack: https://www.healthstacked.com/aasthajs
TIMESTAMPS:
0:00 Why deuterium might be the most important molecule you've never heard of
5:09 The hidden reason processed food is wrecking your health
7:25 How deuterium breaks your mitochondria
11:02 Glyphosate stops your body from rationing deuterium (and the osteoporosis link)
18:23 Health Stacked
19:07 No one is connecting gut health to deuterium, until now
22:45 The two nutrients that help your gut clear deuterium
25:29 Methylation, melatonin, and protecting your mitochondria
33:14 Why melatonin supplements don't actually work
34:08 The two supplements you should stop taking immediately
38:06 How to make your gut produce low-deuterium water
41:12 How glyphosate suppresses your MTHFR gene
43:21 Why folate supplementation is a problem
45:06 "I don't believe in supplements", Stephanie's case against them
46:02 Why she's suspicious of fish oil
47:47 The folic-acid-in-pregnancy and autism connection
52:37 How glyphosate is quietly causing bone problems
56:22 Inflammation is really a deuterium problem
1:01:25 Gerald Pollack's EZ water and how your cells expel deuterium
1:04:59 Why breast milk is low in deuterium
1:09:03 Cancer's real job: repairing your mitochondria (and why chemo may be a mistake)
1:23:14 How deuterium-depleted water may help heal cancer
1:26:57 Deuterium and Parkinson's: how plaque traps it
1:30:37 How to fight Parkinson's
1:33:55 Why Stephanie drinks deuterium-depleted water every day
1:36:37 What glyphosate does to your sulfation system
1:38:38 How grounding reduces deuterium
1:39:42 Jack Kruse on glyphosate and melanin
1:40:08 Are seed oils high in deuterium?
1:45:05 Does where you live (and sunlight) affect your deuterium?
1:47:05 Practical tips to manage your deuterium load
Dr. STEPHANIE SENEFF:
Website: https://stephanieseneff.net/
X: https://x.com/stephanieseneff
AASTHA, LIVE LONGER WORLD:
Join 2,000+ others for practical health protocols on circadian alignment, light, sleep, & non-toxic living: https://livelongerworld.com/
X: https://x.com/aasthajs
Instagram: https://www.instagram.com/aasthajs/
My health stack: https://www.healthstacked.com/aasthajs
Introducing HEALTH STACKED: https://www.healthstacked.com/
I built the health store I’ve always wanted. Health Stacked is a vetted marketplace of 500+ health & longevity products across 12 categories like sleep, fitness, non-toxic home, lighting & EMF, and more. Products are screened for plastic, PFAS, and 20+ toxins. Inclusion is 100% merit-based. And every product has been hand-picked by me.
RELATED EPISODES:
Glyphosate Toxicity & Deuterium's Role in Cancer, Celiac, Aging | Dr. Stephanie Seneff: https://open.spotify.com/episode/4HFmNT0fLCckXvrC1XRSFt?si=cSv7wuPPTm2wE5YSMY2L3w
The standard “wear and tear” story of aging may be incomplete. Dr. Peter Lidsky—a virologist and evolutionary biologist argues that aging is programmed. He says aging can be an adaptive strategy for controlling pathogens, a concept he calls the “pathogen control hypothesis.”
In this episode, we dig into the evidence behind this idea, the immune system in aging, and what his theory means for longevity interventions.
Episode Show Notes: https://livelongerworld.com/p/plidskyFind me: https://x.com/aasthajs My longevity products: https://www.livelongerworld.com/p/2024TIMESTAMPS:0:00 — Aging ≠ Wear-and-Tear
3:44 — The Case for Programmed Aging
8:48 — Why Program Aging at All?
11:09 — The Pathogen-Control Hypothesis
14:26 — Why We Get “Sick Time”
24:37 — Rising Lifespans, Explained
27:36 — Bowhead Whales’ Longevity Edge
31:15 — Why Lone Animals Don’t Live Forever
34:00 — Planaria: The “Immortal” Worm
35:00 — Do Infections Speed Up Aging?
36:46 — When Immunity Starts to Slide
38:17 — Why Fertility Has a Deadline
42:49 — Extending Life via the Immune System
1:00:35 — How Honey Bees Rejuvenate
1:10:50 — Can We Tackle Aging? Healthspan to 90s+AASTHA, LIVE LONGER WORLD:X: https://x.com/aasthajs Newsletter: https://livelongerworld.com/Instagram: https://www.instagram.com/aasthajs/Peter Lidsky: https://www.cityu.edu.hk/bms/profile/peterlidsky.htmRELATED:Dr. Geoffrey West | Scaling Laws in Longevity & Aging: https://youtu.be/T67U8IK_1RU?si=ajq5AbjM6ufBQ7WfDr. David Gems | Hyperfunction & Programmatic Theory of Aging & Critique of Hallmarks of Aging: https://youtu.be/rLD-8UhHEZM?si=R_x_mLguTAKfdXtQDr. Bjorn Schumacher | DNA Damage & Aging, p53 & Cancer, and DNA repair in Reproductive Cells: https://youtu.be/kjQ-SwEP1bo?si=G2mEtNZs1O7TsLKe
“We can use the rule of evolution to optimize cancer therapy. The standard practice is that any therapy is given at maximum tolerated dose continuously until progression. It's almost a mantra that they have. Evolutionarily, you could hardly do it worse.” The current treatments on cancer do not account for how evolution works. Dr. Robert Gatenby has been studying evolutionary and game theory dynamics in the progression of cancer. He established the first cancer biology and evolutionary program in the U.S. We can leverage this evolutionary information to provide more effective cancer treatment, which he discusses in this episode. Dr. Michael Levin is my co-host.Episode Show Notes: https://livelongerworld.com/p/rgatenbyFind me: https://x.com/aasthajs My longevity products: https://www.livelongerworld.com/p/2024TIMESTAMPS:0:00 – Cancer as Tissue Damage, Not Just Mutations8:48 – How Evolution Supercharges Cancer Cell Fitness11:04 – Debunking the “Primitive Cell” Myth12:06 – The Herd Mentality of Cancer Cells14:57 – Why Cancer Dynamics Go Beyond the Genome22:27 – Networks and Information Flow Inside Cells26:56 – Shared Goals: The Secret to Cellular Cooperation29:55 – Genome = Hardware, Information = Software36:26 – Healthy vs. Cancer Cells: Competing Information Systems39:05 – Evolution Turns Harsh After Reproduction41:03 – How Cancer Rewrites Its Own Information Playbook43:07 – Adaptive Therapy: A Patient’s Guide50:45 – The Limits of Adaptive Therapy53:12 – Hunting for Better Cancer Biomarkers55:11 – The Tumor Microenvironment’s Hidden Role59:42 – Why We Must Look Beyond Genetic DataAASTHA, LIVE LONGER WORLD:X: https://x.com/aasthajs Newsletter: https://livelongerworld.com/Instagram: https://www.instagram.com/aasthajs/LINKS:Michael Levin: https://x.com/drmichaellevinRobert Gatenby: https://www.moffitt.org/inspiring-stories/dr.-gatenbys-storyEpisode Show Notes: https://livelongerworld.com/p/rgatenbyALSO WATCH:The First Cancer Cell: A Revolution in Early Detection | Michael Levin & Azra Raza: https://open.spotify.com/episode/7yW6ZVVdQkboWpldUZyenD?si=obYEC22NSsSyy7j09JBf7QKeto & Metabolic Therapy for Cancer | Dr. Thomas Seyfried: https://open.spotify.com/episode/7tYdjcJ3G4tqbAx9Z6Bix2?si=Yz9CQ-wNQ3WdcwjKw3lXGwWhy Viruses Could Be the Cause of Chronic Disease | Dr. Paul Ewald: https://open.spotify.com/episode/2OdYInlzTy2zG3Mi6TgADY?si=BtishVk_R-28K2KypODIog
Mitochondria might be one of the most important organelles inside our cells. Best known as the cell’s powerhouse, they don’t just make energy; they regulate metabolism, control cell death, drive immune function, and may even be the reason multicellular life exists at all!
It’s no surprise they’re implicated in nearly every major disease, from heart disease and cancer to neurodegeneration, especially as they decline with age. What if we could slow or even reverse that decline by giving cells fresh, healthy mitochondria? That’s the promise of mitochondrial transplantation—a groundbreaking approach Mitrix Bio is pioneering.
In this episode, I talk with CEO Tom Benson about the science, the potential, and the early results from people already lining up for their trial.
Episode Show Notes: https://livelongerworld.com/p/tbenson
Find me: https://x.com/aasthajs
My longevity products: https://www.livelongerworld.com/p/2024
TIMESTAMPS:
00:00 - Injecting new mitochondria into your body
01:39 - Mitochondria’s evolutionary role in aging
04:35 - What happens to old mitochondria?
06:18 - Why humans live longer than other animals
11:30 Why cardiovascular disease is #1 killer
12:30 - Why does the brain remain sharp with age?
15:30 Why does energy decline after age 30?
19:04 Why doesn’t the body correct mitochondrial mutations?
22:42 Mitochondrial defects in children
24:14 Diagnostics for mitochondrial health
27:36 Mitochondrial DNA is eternal
33:18 Where does mitochondria come from in mitochondrial transplantation?
34:59 Growing mitochondria in a bioreactor
39:07 How neurons grow their mitochondria
40:52 Mitochondrial theory of cancer
44:23 Mitochondria and psychobiology
48:32 Chemotherapy and radiation damage mitochondria
50:38 Evidence that mitochondrial transplantation works
56:06 Caloric restriction, sauna, sunlight, and mitochondria
1:00:01 Mitochondria and races
1:02:57 Why stop at 130 years old?
1:04:48 Why might this not work?
1:10:03 Volunteers for Mitrix trial
AASTHA, LIVE LONGER WORLD:
X: https://x.com/aasthajs
Newsletter: https://livelongerworld.com/
Instagram: https://www.instagram.com/aasthajs/
Mitrix Bio:
https://mitrix.bio/
Tom Benson: https://mitrix.bio/team/tom-benson/
RELATED:
New Spin to the Free Radical Theory of Aging: https://www.livelongerworld.com/p/ros
Keto & Metabolic Therapy for Cancer | Dr. Thomas Seyfried: https://open.spotify.com/episode/7tYdjcJ3G4tqbAx9Z6Bix2?si=biOOH1e5RpeZduLJv2fPHw
Boost Mitochondria with Sunlight and Infrared light: https://open.spotify.com/episode/1jGfhzX1P245LU2kLwgHTq?si=yPOC3bViRnmOUeR-P0jeWA
Can we detect cancer so early such that we find the very first cell of cancer? Not just stage 1 cancer, but the first cell of cancer.
In this episode, Dr. Michael Levin and I speak with Dr. Azra Raza. She is an oncologist pioneering early detection of cancer using electric signals. So far, our best solution to curing cancer has been to detect it early, and she wants to take this further, by nipping cancer at the very first cell.
Her story with cancer is also deeply personal as she lost her husband to the disease. You can see in the episode how much she cares about solving cancer through early detection, and how aggrieved she is about the fact that not only have we made zero progress on cancer in the last 100 years, but doctors are also not focused on cancer prevention.
Dr. Raza is also the author of the book The First Cell: And the Human Costs of Pursuing Cancer to the Last.
Episode Show Notes: https://livelongerworld.com/p/araza
Find me: https://x.com/aasthajs
My longevity products: https://www.livelongerworld.com/p/2024
TIMESTAMPS:
0:00 New theory of cancer
1:45 What causes cancer?
5:39 Hybrid cells in cancer
11:16 Why do cancer cells become immortal?
14:14 Detecting the first cell of cancer
17:09 Stress causes cancer cells to fuse
21:40 Cancer drugs don’t work universally
25:54 Personalization of early cancer detection
29:29 Detect cancer early using electrics
35:46 Anguish of cancer patients
39:06 Cancer progress hasn’t moved in 100 years
44:04 Doctors don’t think of cancer prevention
46:54 First Cell Therapeutics - Azra’s company
50:55 What is the first cell stage of cancer?
54:55 Advice for cancer patients
AASTHA, LIVE LONGER WORLD:
Twitter: https://x.com/aasthajs
Newsletter: https://livelongerworld.com/
Instagram: https://www.instagram.com/aasthajs/
LINKS:
Michael Levin: https://twitter.com/drmichaellevin
Azra Raza: https://azraraza.com/
Azra Raza book The First Cell: https://amzn.to/4jGJzoJ
Episode Show Notes: https://livelongerworld.com/p/araza
RELATED EPISODES:
Keto & Metabolic Therapy for Cancer | Dr. Thomas Seyfried: https://open.spotify.com/episode/7tYdjcJ3G4tqbAx9Z6Bix2?si=gboyPAiLQrqg-y5YEKQiQQ
Why Viruses Could Be the Cause of Chronic Disease | Dr. Paul Ewald: https://open.spotify.com/episode/2OdYInlzTy2zG3Mi6TgADY?si=Gnbg7efNSy21bS3q0c23jg
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