Lost Women of Science

 “The only time I ever saw something that I thought was abnormal…there was a human arm in the refrigerator,” said J. Peter Willard about his aunt, Mary Louisa Willard. Otherwise, he insisted, she was just “very normal.” But Mary Louisa Willard, a chemistry professor at Pennsylvania State University in the late 1920s, left a strong impression on most people, to say the least. Her hometown of State College, Pennsylvania, knew her for stopping traffic in her pink Cadillac to chat with friends and for throwing birthday bashes for her beloved cocker spaniels. Police around the world knew her for her side hustle: using chemistry to help solve crimes.

When Laura J. Martin decided to write a history of ecological restoration, she didn’t think she would have to go back further than the 1980s to uncover its beginnings. What she found, however, deep in the archives, was evidence of a network of early female botanists from the turn of the last century who had been written out of history. Wild by Design: The Rise of Ecological Restoration sets the record straight. It tells the stories of Eloise Butler, Edith Roberts and the wild and wonderful gardens they planted and studied. 

In our final episode, we explore Dorothy Andersen’s legacy — what she left behind and how her work has lived on since her death. Describing her mentor’s influence on her life and career, Dr. Celia Ores gives us a rare look at what Dr. Andersen was really like. We then turn to researchers, physicians, and patients, who fill us in on the many areas of progress that have grown out of Dr. Andersen’s work. These major developments include the discovery of the cystic fibrosis gene, the tremendous impact of the drug Trikafta, and the lifesaving potential of gene editing techniques. We end the episode with an update on the effect Trikafta has had on the lives of many CF patients, who can now expect to live a normal life. 

The missing portrait of Dr. Andersen takes us on a journey into the perils of memorialization and who gets to be remembered. Dr. John Scott Baird, Dorothy Andersen’s biographer, looks for the portrait, and Drs. Nientara Anderson and Lizzy Fitzsousa, former medical students at Yale University, explain how “dude walls” — the paintings of male scientists that line institutional walls — can have an insidious effect on those who walk past them every day. And we go back to Columbia University to give you an update on the hunt for the missing portrait.

Our associate producer, Sophie McNulty, rummages through boxes in a Connecticut basement, looking for clues to Dorothy Andersen’s life story. Pediatric critical care physician Dr. John Scott Baird, who published a biography of Dorothy Andersen in 2021, suggests we take a second look at the conventional wisdom surrounding the evolution of cystic fibrosis research in the 1950s. And in this updated episode, we interview science historian Margaret Rossiter, who coined the term “Matilda Effect” to describe how credit for work done by female scientists too often goes to their male colleagues. We examine how this affected Dorothy Andersen and her groundbreaking research into cystic fibrosis.

A few important things have happened in the three years since we first aired The Pathologist in the Basement, the story of Dr. Dorothy Andersen, the first to identify cystic fibrosis. It’s safe to say that Dr. Anderson is now a little less lost. In Episode 1, Dr. Andersen sleuths her way to the discovery of cystic fibrosis, a fatal disease that affects the lungs, the pancreas, and a host of other organs. So, who was Dorothy Andersen, and how did she come to make this seminal medical contribution?

When poet Jessy Randall started researching the lives of female scientists she became angry. And we certainly can relate here at Lost Women of Science. So many women made important discoveries but received little recognition. In this episode of Lost Women of Science Conversations, Randall talks to Carol Sutton Lewis about Mathematics for Ladies: Poems on Women in Science, the collection of poems born of that anger. They discuss what it means to be the first in a field, the ethics of poetic license, and the importance of female role models in STEM. Randall’s poems are about some of the women we’ve featured in our podcast, including the first Black female doctor, Rebecca Lee Crumpler, and the physicist Lise Meitner.

“We were each put on earth to torment the other,” says cognitive scientist Steven Pinker of Elizabeth Bates, a psychologist who challenged the prevailing theory about how humans acquire language. Bates believed that language emerges from interactions between our brains and our environments, and that we do not have an innate language capacity. To many, that sounds like an innocuous statement. But in making these claims, Bates challenged formidable linguists like Pinker and Noam Chomsky, placing herself at the center of a heated debate that remains unresolved half a century later.

Melba Phillips, who grew up on a farm in Indiana at the turn of the 20th century, was one of J. Robert Oppenheimer’s first graduate students at the University of California, Berkeley. Together they discovered the Oppenheimer-Phillips Process, which explained a particular kind of nuclear reaction. In this episode, we explain what that is, with a little help from generative AI. Phillips did not follow Oppenheimer to Los Alamos, and was vocal in her opposition to nuclear weapons. During the McCarthy era, she lost her teaching job, and did not return to academia until 1957. In 1962, then in her mid-fifties, she finally became a full professor at the University of Chicago.

Cecilia Payne-Gaposchkin was in her early 20s when she figured out what the stars are made of. Both she and her groundbreaking findings were ahead of their time. Continuing the legacy of women working at the Harvard College Observatory, Cecilia charted the way for a generation of female astronomers to come. This Best Of episode of Lost Women of Science follows Cecilia’s journey of discovery, journals her drive and determination against all odds, and takes you to the Harvard College Observatory itself to walk in Cecilia’s footsteps.