Dr. Chapa’s OBGYN Clinical Pearls

MATISSE Trial: Maternal RSV Vaccine Outcomes


Listen Later

In most regions of the United States, RSV season starts in the fall and peaks in the winter. In September 2023, the ACOG released a Practice Advisory recommending a single dose of Pfizer’s RSV vaccine (Abrysvo) for eligible pregnant individuals between 32 0/7 and 36 6/7 weeks of gestation who do not have a planned delivery within 2 weeks, using seasonal administration, to prevent RSV lower respiratory tract infection (LRTI) in infants. This is recommended from September to January. Currently, the US recommendation is for this to be given once, with subsequent deliveries receiving neonatal Beyfortus in RSV season. The recommendation from NICE is to have this vaccination with every pregnancy. The prescribing information for Abrysvo includes a warning to inform patients that a numerical imbalance in preterm births in Abrysvo recipients (5.7%) occurred compared to those who received placebo (4.7%). This imbalance was only seen in trial participants residing in low- to middle-income countries with no temporal association to vaccination or association with other adverse events in the mother or the newborn. Now, that phase 3 clinical data has gone through peer review and is a new publication. This is the MATISSE global study and will be officially published in the Green Journal February 2025…but we will summarize the results NOW in this episode! Listen in for details.

...more
View all episodesView all episodes
Download on the App Store

Dr. Chapa’s OBGYN Clinical PearlsBy Dr. Chapa’s Clinical Pearls

  • 4.2
  • 4.2
  • 4.2
  • 4.2
  • 4.2

4.2

419 ratings


More shows like Dr. Chapa’s OBGYN Clinical Pearls

View all
AFP: American Family Physician Podcast by American Academy of Family Physicians

AFP: American Family Physician Podcast

701 Listeners

JAMA Clinical Reviews by JAMA Network

JAMA Clinical Reviews

500 Listeners

The Green Room: A Podcast from Obstetrics & Gynecology by Obstetrics & Gynecology (Green Journal)

The Green Room: A Podcast from Obstetrics & Gynecology

70 Listeners

Frankly Speaking About Family Medicine by Pri-Med

Frankly Speaking About Family Medicine

259 Listeners

The Curbsiders Internal Medicine Podcast by The Curbsiders Internal Medicine Podcast

The Curbsiders Internal Medicine Podcast

3,339 Listeners

Core IM | Internal Medicine Podcast by Core IM Team

Core IM | Internal Medicine Podcast

1,149 Listeners

Evidence Based Birth® by Rebecca Dekker, PhD, RN

Evidence Based Birth®

1,010 Listeners

Health By Heather Hirsch by Heather Hirsch

Health By Heather Hirsch

215 Listeners

CREOGs Over Coffee by CREOGs Over Coffee

CREOGs Over Coffee

553 Listeners

As a Woman by Natalie Crawford, MD

As a Woman

1,099 Listeners

You Are Not Broken by Kelly Casperson, MD

You Are Not Broken

1,061 Listeners

The Critical Care Obstetrics Podcast by Clinical Concepts in Obstetrics

The Critical Care Obstetrics Podcast

212 Listeners

The Cribsiders by The Cribsiders

The Cribsiders

315 Listeners

Dr. Streicher’s Inside Information: Menopause, Midlife, and More by Lauren Streicher, MD

Dr. Streicher’s Inside Information: Menopause, Midlife, and More

367 Listeners

Point Me To First Class by Devon Gimbel MD

Point Me To First Class

1,175 Listeners