Derms on Drugs

Melanoma Meltdowns, Biosimilar Betrayals, and the Eczema Enigma Exposed!


Listen Later

Buckle-up Kids.  Our Derms on Drugs are answering some of the hottest questions in dermatology again this week:

  • Melanoma's Mental Massacre: Discover which patients are most likely to spiral into anxiety and depression after diagnosis and how we can help save their sanity!
  • Biosimilar Backstabbing: Why do patients switched to biosimilars fare worse than newbies to psoriasis? We'll peel back the layers of this pharmaceutical puzzle.
  • Eczema Epidemic Exposed: Hold onto your moisturizers, folks! We've cracked the code on why everyone and their itchy grandmother has atopic dermatitis. Spoiler alert: It's not just your genes being jerks!
  • Air Pollution: The Silent Skin Assassin: Dr. Ian Myles spills the tea on how he caught air pollution red-handed in the great eczema explosion of the '70s. Urban dwellers, your skin's arch-nemesis has been unmasked!

  • But wait, there's more! We'll also dive into:

    • The return of the zit: Predicting acne's revenge after isotretinoin
    • Dupilumab: The accidental cancer crusader?
    • Tralokinumab: Savior for dupilumab dropouts or just another letdown?
    • Ferulic acid vs. Rosacea: The face-off you never knew you needed
    • Cysteamine and hydroquinone duke it out in the melasma arena
    • Digital mucous cysts: Because even your fingers deserve some drama

    • You’ll laugh, you’ll cry, you might even learn something new… Join Drs. Ferris, Zirwas and Patton for a new episode every Friday

      Derms on Drugs is produced by ⁠Scholars in Medicine.⁠


      Guest: Ian A. Myles, MD, Mph

      Guest Bio: Dr. Myles, Principal Investigator, Epithelial Therapeutics Unit, graduated with a B.S. in biology from Colorado State University in 2001 and then obtained an M.D. from the University of Colorado in 2005. He completed an internal medicine residency at The Ohio State University prior to beginning fellowship training in allergy and clinical immunology at NIH. He worked under the mentorship of Dr. Sandip Datta investigating the mechanistic details of susceptibility to S. aureus skin infections. In 2011, Dr. Myles became a commissioned officer in the United States Public Health Service Commissioned Corps. LCDR Myles has supported several USPHS missions, from the Ebola virus vaccine trial in West Africa to congressional Gold Medal Ceremonies at the U.S. Capitol. In 2013, he was awarded a position as an assistant clinical investigator in the NIAID Transition Program in Clinical Research. Dr. Myles received his M.P.H. from George Washington University in 2016. In 2018, Dr. Myles became the head of the newly formed Epithelial Therapeutics Unit to evaluate the efficacy and safety of a topical, live bacterial treatment for atopic dermatitis (eczema). He is currently a participant in the Lasker Clinical Research Scholars and Distinguished Scholars programs.


      Links to Articles and Websites

      1.  Prevalence and odds of anxiety and depression in cutaneous malignant melanoma: a proportional meta-analysis and regression

      2.  Drug Survival and Safety of Biosimilars Compared with Originator Adalimumab for Psoriasis: A Multinational Cohort Study

      3.  The clinical, mechanistic, and social impacts of air pollution on atopic dermatitis

      4.  Exposure to isocyanates predicts atopic dermatitis prevalence and disrupts therapeutic pathways in commensal bacteria

      5.  Environmental and behavioral mitigation strategies for patients with atopic dermatitis

      6.  Acne Relapse and Isotretinoin Retrial in Patients With Acne

      7.  Risk of malignancy associated with use of dupilumab versus other treatments in atopic dermatitis patients: A national database analysis

      8.  Tralokinumab Treatment in Adult Atopic Dermatitis Patients: 28-Week Evaluation of Clinical Effectiveness, Safety, Serum Proteins and Total IgE Levels

      9.  Ferulic Acid in the Treatment of Papulopustular Rosacea: A Randomized Controlled Study

      10.  Efficacy and safety of cysteamine 5% cream for the management of melasma: a systematic review and meta-analysis of randomized controlled trials

      11.  Effectiveness of surgical versus non-surgical interventions in treatment of digital mucous cysts


      Melanoma Prognosis Calculator

      http://www.lifemath.net/cancer/melanoma/outcome/index.php

       

      Skinesa Defensin+ Probiotic Spray

      https://www.skinesa.com/products/defensin-probiotic-spray

      ...more
      View all episodesView all episodes
      Download on the App Store

      Derms on DrugsBy Scholars in Medicine

      • 4.7
      • 4.7
      • 4.7
      • 4.7
      • 4.7

      4.7

      15 ratings


      More shows like Derms on Drugs

      View all
      Wait Wait... Don't Tell Me! by NPR

      Wait Wait... Don't Tell Me!

      38,603 Listeners

      Radiolab by WNYC Studios

      Radiolab

      43,836 Listeners

      This American Life by This American Life

      This American Life

      90,809 Listeners

      Marketplace by Marketplace

      Marketplace

      8,587 Listeners

      Planet Money by NPR

      Planet Money

      30,891 Listeners

      Freakonomics Radio by Freakonomics Radio + Stitcher

      Freakonomics Radio

      32,108 Listeners

      Hidden Brain by Hidden Brain, Shankar Vedantam

      Hidden Brain

      43,250 Listeners

      The Curbsiders Internal Medicine Podcast by The Curbsiders Internal Medicine Podcast

      The Curbsiders Internal Medicine Podcast

      3,329 Listeners

      The Daily by The New York Times

      The Daily

      111,470 Listeners

      Up First from NPR by NPR

      Up First from NPR

      56,179 Listeners

      The Peter Attia Drive by Peter Attia, MD

      The Peter Attia Drive

      7,770 Listeners

      Dermasphere - The Dermatology Podcast by Luke Johnson

      Dermasphere - The Dermatology Podcast

      139 Listeners

      You Are Not Broken by Kelly Casperson, MD

      You Are Not Broken

      896 Listeners

      The Ezra Klein Show by New York Times Opinion

      The Ezra Klein Show

      15,336 Listeners

      Derms and Conditions by Dermsquared

      Derms and Conditions

      47 Listeners