Weight gain is a typical side-effect of taking antipsychotics and can have a big impact on people. But for young people with bipolar disorder, metformin isn't commonly prescribed alongside an antipsychotic. In this episode, Melissa DelBello describes a huge randomised trial in the USA on metformin for young people with bipolar disorder taking antipsychotics, looking at its effects over a 2-year period.

Click here to read the full article: https://www.thelancet.com/journals/lanpsy/article/PIIS2215-0366(25)00273-1/fulltext

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