LessWrong (30+ Karma)

“Mirror Organisms Are Not Immune to Predation” by Matthias Dellago


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Core Argument

The barrier to preying on "mirror-image" life is likely lower than presumed due to:

  1. Immediate energy from achiral fats.
  2. Existing L-sugar pathways.
  3. Existing D-amino acid racemases.
  4. 1. Fats: Achiral Energy Bridge

    Lipids (triglycerides), largely achiral, offer immediate energy. In E. coli for example, they constitute ~10% of dry mass, yielding ~27% of its macronutrient calories[1]). This non-chiral caloric gain from mirror prey could sustain predators during adaptation to chiral components.

    2. Carbohydrates: L-Glucose Metabolism Evolved

    L-glucose metabolism has evolved at least twice despite its rarity in nature:

    • Pseudomonas caryophylli enzyme oxidizes L-glucose (Sasajima & Sinskey, 1979[2]).
    • Paracoccus sp. 43P has a full L-glucose catabolic pathway (Shimizu et al., 2012[3]).
    • This capacity for mirror-sugar adaptation, emerging even under low selective pressure, suggests the evolutionary barrier to such adaptations might be lower than anticipated.

      [...]

      ---

      Outline:

      (00:10) Core Argument

      (00:30) 1. Fats: Achiral Energy Bridge

      (00:56) 2. Carbohydrates: L-Glucose Metabolism Evolved

      (01:35) 3. Proteins: Racemases Handle D-Amino Acids

      (02:09) Conclusion: Lowered Mirror Predation Barrier

      The original text contained 4 footnotes which were omitted from this narration.

      ---

      First published:

      May 22nd, 2025

      Source:

      https://www.lesswrong.com/posts/zA6HWeoMeJWcrsfgK/mirror-organisms-are-not-immune-to-predation

      ---

      Narrated by TYPE III AUDIO.

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