In Part 1 of Mission RENAL, a series on Chronic Kidney Disease (CKD) in pets, Dr. JD Foster, small animal internal medicine and nephrology expert joins to explain the difference between Acute Kidney Injury (AKI) and CKD, why many CKD cases have no single cause, the early warning signs and why these signs happen, the power of early screening to slow progression, and how staging CKD guides individualized care.

• CKD is irreversible but manageable—early detection matters.

• PU/PD (peeing/drinking more) is often the first clue; appetite changes are common.

• Pets can act normal with substantial kidney function loss—don't wait on labs.

• Wellness bloodwork + urinalysis help slow the disease early.

• Staging organizes care so your pet gets the right support at the right time.

Resources & Links:

• Episode page with pictures and video: Mission RENAL Part 1: Understanding Chronic Kidney Disease in Pets

• Find a veterinary internal medicine specialist near you: Specialist Search Here

Our vision is for Your Vet Wants You to Know to be a resource for veterinarians to improve client communication by introducing a discussion about a common topic during the vet visit, then directing the client to a reliable source of engaging, understandable, and accessible information.

By doing so, we strive for: 1) increased pet health literacy among pet owners, 2) improved partnership between clients and the veterinary team, 3) improved medical outcomes for pets, and 4) improved quality of life and efficiency for veterinarians.

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Mission RENAL is sponsored by Royal Canin and Elanco™ makers of VarenzinTM-CA1 (molidustat oral suspension).

Varenzin-CA1 is indicated for the control of nonregenerative anemia associated with chronic kidney disease (CKD) in cats.

Important Safety Information

Varenzin-CA1 is for oral use in cats only and prescribed only by licensed veterinarians. Keep this drug and used syringes out of reach of children. Wash hands immediately after use. In case of accidentally swallowing, call a doctor immediately. Women who are or may become pregnant should use the product with caution. Do not give to pregnant, nursing or breeding cats. Before using Varenzin-CA1, talk to your veterinarian if your cat is allergic to molidustat, has a history of seizures or thromboembolic disease predisposition. Use with caution in cats younger than 1 year of age. Common side effects include vomiting and high blood pressure. Red blood cell proportion should be monitored. Click here for complete safety information.