In this episode, Dr. Mandy Sorensen reviews major One Health updates, including a sharp rise in avian influenza cases, ongoing concerns about New World Screwworm, and important winter safety risks for pets. The conversation highlights the scale of recent poultry losses and spillover risks to mammals, including pets. New conditional treatment options for screwworm in dogs are approved, but early recognition and reporting are crucial. The episode closes with reflections on global disease surveillance through the WHO, collaboration, and encouraging developments in public health leadership from the American Academy of Pediatrics.

• Avian influenza activity has surged, with millions of birds affected and increased risk to wildlife and domestic animals.

• Outdoor pets, especially cats, face exposure risks through contact with infected birds.

• New World Screwworm continues to move north, making awareness and rapid reporting essential for veterinarians.

• Cold weather hazards such as de-icers and antifreeze pose preventable risks to pets.

• Strong global collaboration remains critical for effective disease surveillance and response.

• The American Academy of Pediatrics has released evidence-based vaccine recommendations.

Pet owners and veterinary professionals, sign up for our newsletter here: https://www.yourvetwantsyoutoknow.com/newsletter

Veterinarians are invited to join the American Association of Food Safety and Public Health Veterinarians.

Help support our mission through BUY ME A COFFEE: https://buymeacoffee.com/yourvet

Our vision is for Your Vet Wants You to Know to be a resource for veterinarians to improve client communication by introducing a discussion about a common topic during the vet visit, then directing the client to a reliable source of engaging, understandable, and accessible information.

By doing so, we strive for: 1) increased pet health literacy among pet owners, 2) improved partnership between clients and the veterinary team, 3) improved medical outcomes for pets, and 4) improved quality of life and efficiency for veterinarians.

Connect with Your Vet! Instagram: https://www.instagram.com/yourvetwantsyoutoknow Facebook: https://www.facebook.com/yourvetwantsyoutoknow Facebook group: https://www.facebook.com/groups/yourvetwantsyoutoknow

In Part 5 of Mission RENAL, a series on Chronic Kidney Disease (CKD) in pets, Dr. JD Foster, small animal internal medicine and nephrology expert joins to discuss non-regenerative anemia in cats with chronic kidney disease and introduce Varenzin™-CA1 (molidustat oral suspension), the first FDA conditionally approved oral treatment for this condition. They explain why non-regenerative anemia matters, how it affects quality of life, and how this innovative medication works differently from older therapies. Sponsored by Elanco, this guide empowers pet owners with Real Education for Navigating Advanced Longevity in dogs and cats with chronic kidney disease.

Key Takeaways:

• Non-regenerative anemia is a common and expected complication of advanced CKD in cats

• Treating non-regenerative anemia can improve energy, appetite, and overall quality of life

• Varenzin™-CA1 works by restoring the cat's own erythropoietin production

• Earlier treatment of non-regenerative anemia may help reduce disease progression stress

• Oral administration improves compliance and reduces owner-cat stress

Please note: Varenzin-CA 1 (molidustat oral suspension) is indicated for the control of non-regenerative anemia associated with chronic kidney disease (CKD) in cats. Discussions within this podcast pertaining to treating anemia with Varenzin-CA1 are solely pertaining to the treatment of CKD-related non-regenerative anemia.

Resources & Links:

• Episode page with pictures and video: Mission RENAL Part 5: Varenzin-CA1 for Non-Regenerative Anemia in Cats with Chronic Kidney Disease

• Find a veterinary internal medicine specialist near you: Specialist Search Here

Our vision is for Your Vet Wants You to Know to be a resource for veterinarians to improve client communication by introducing a discussion about a common topic during the vet visit, then directing the client to a reliable source of engaging, understandable, and accessible information.

By doing so, we strive for: 1) increased pet health literacy among pet owners, 2) improved partnership between clients and the veterinary team, 3) improved medical outcomes for pets, and 4) improved quality of life and efficiency for veterinarians.

Help support our mission through BUY ME A COFFEE: https://buymeacoffee.com/yourvet

Connect with Your Vet! Instagram: https://www.instagram.com/yourvetwantsyoutoknow Facebook: https://www.facebook.com/yourvetwantsyoutoknow Facebook group: https://www.facebook.com/groups/yourvetwantsyoutoknow

Mission RENAL is sponsored by Royal Canin and Elanco™ makers of VarenzinTM-CA1 (molidustat oral suspension).

Varenzin™-CA1 is indicated for the control of nonregenerative anemia associated with chronic kidney disease (CKD) in cats.

Important Safety Information

Varenzin™-CA1 is for oral use in cats only and prescribed only by licensed veterinarians. Keep this drug and used syringes out of reach of children. Wash hands immediately after use. In case of accidentally swallowing, call a doctor immediately. Women who are or may become pregnant should use the product with caution. Do not give to pregnant, nursing or breeding cats. Before using Varenzin™-CA1, talk to your veterinarian if your cat is allergic to molidustat, has a history of seizures or thromboembolic disease predisposition. Use with caution in cats younger than 1 year of age. Common side effects include vomiting and high blood pressure. Red blood cell proportion should be monitored. Click here for complete safety information.

January is One Health Month and we are highlighting opportunities for education, career exploration, and collaboration across human, animal, and environmental health. This episode provides updates on ongoing One Health threats, including avian influenza, New World Screwworm, and wildlife rabies, with practical guidance for veterinarians and the public. A major focus of the discussion introduces PFAS ("forever chemicals"), explaining what they are, why they matter for One Health, and how environmental contamination can impact both human and animal health. The episode closes on an optimistic note with conservation success stories, with the downgrading of Green Sea Turtles from "endagered" to "least concerned," emphasizing the power of science, collaboration, and long-term commitment.

• January is One Health Month, and organizations like AAFSPHV are creating accessible opportunities for students, veterinarians, and professionals to explore One Health opportunities.

• Avian influenza remains an evolving global threat, with over 185 million birds affected since 2022 and ongoing concern about viral reassortment during a severe human flu season.

• New World Screwworm is moving closer to the U.S. border, underscoring the importance of veterinary awareness, surveillance, and preparedness, especially in southern regions.

• Rabies persists in wildlife reservoirs, including foxes, making vaccination, public awareness, and avoidance of wildlife contact critical for protecting pets and people.

• PFAS ("forever chemicals") represent a major One Health challenge, with widespread environmental contamination affecting humans and animals, but emerging research offers promising solutions for reducing exposure, with a new study demonstrating a technique to remove PFAS.

• The American Veterinary Medical Association provides a fact sheet for veterinarians about PFAS.

Pet owners and veterinary professionals, sign up for our newsletter here: https://www.yourvetwantsyoutoknow.com/newsletter

Veterinarians are invited to join the American Association of Food Safety and Public Health Veterinarians.

Help support our mission through BUY ME A COFFEE: https://buymeacoffee.com/yourvet

Our vision is for Your Vet Wants You to Know to be a resource for veterinarians to improve client communication by introducing a discussion about a common topic during the vet visit, then directing the client to a reliable source of engaging, understandable, and accessible information.

By doing so, we strive for: 1) increased pet health literacy among pet owners, 2) improved partnership between clients and the veterinary team, 3) improved medical outcomes for pets, and 4) improved quality of life and efficiency for veterinarians.

Connect with Your Vet! Instagram: https://www.instagram.com/yourvetwantsyoutoknow Facebook: https://www.facebook.com/yourvetwantsyoutoknow Facebook group: https://www.facebook.com/groups/yourvetwantsyoutoknow

In Part 4 of Mission RENAL, a series on Chronic Kidney Disease (CKD) in pets, Dr. JD Foster, small animal internal medicine and nephrology expert joins to explain treatments for hypertension, proteinuria, high phosphorus, and anemia; how IRIS staging affects prognosis; and how to maintain quality of life as CKD progresses. Sponsored by Royal Canin and Elanco, this guide empowers pet owners with Real Education for Navigating Advanced Longevity in dogs and cats with chronic kidney disease.

• How medications support kidney health in pets with CKD

• Why treating anemia, hypertension, and proteinuria slows disease progression

• How phosphate binders and FGF-23 testing help protect kidney function

• Understanding IRIS staging and what it means for prognosis

• What signs indicate CKD is moving into a more advanced stage

• Tips for maintaining comfort, appetite, and quality of life

Resources & Links:

• Episode page with pictures and video: Mission RENAL Part 4: Mediations for Pets with Chronic Kidney Disease

• Find a veterinary internal medicine specialist near you: Specialist Search Here

Our vision is for Your Vet Wants You to Know to be a resource for veterinarians to improve client communication by introducing a discussion about a common topic during the vet visit, then directing the client to a reliable source of engaging, understandable, and accessible information.

By doing so, we strive for: 1) increased pet health literacy among pet owners, 2) improved partnership between clients and the veterinary team, 3) improved medical outcomes for pets, and 4) improved quality of life and efficiency for veterinarians.

Help support our mission through BUY ME A COFFEE: https://buymeacoffee.com/yourvet

Connect with Your Vet! Instagram: https://www.instagram.com/yourvetwantsyoutoknow Facebook: https://www.facebook.com/yourvetwantsyoutoknow Facebook group: https://www.facebook.com/groups/yourvetwantsyoutoknow

Mission RENAL is sponsored by Royal Canin and Elanco™ makers of VarenzinTM-CA1 (molidustat oral suspension).

Varenzin-CA1 is indicated for the control of nonregenerative anemia associated with chronic kidney disease (CKD) in cats.

Important Safety Information

Varenzin-CA1 is for oral use in cats only and prescribed only by licensed veterinarians. Keep this drug and used syringes out of reach of children. Wash hands immediately after use. In case of accidentally swallowing, call a doctor immediately. Women who are or may become pregnant should use the product with caution. Do not give to pregnant, nursing or breeding cats. Before using Varenzin-CA1, talk to your veterinarian if your cat is allergic to molidustat, has a history of seizures or thromboembolic disease predisposition. Use with caution in cats younger than 1 year of age. Common side effects include vomiting and high blood pressure. Red blood cell proportion should be monitored. Click here for complete safety information.

In this One Health Heroes update, Dr. Mandy Sorensen, communication specialist with the American Association of Food Safety and Public Health Veterinarians, discusses:

• ​Avian influenza remains a global One Health threat, with over 800,000 poultry cases in the past 30 days and new spillover events from wild birds into dairy cattle, creating opportunities for viral adaptation.
• ​Companion animals are at risk through wildlife exposure, as seen in fatal avian influenza cases involving kittens in Europe and a dog in Canada after ingesting infected birds.
• ​A rabies-positive dog in Chicago highlights rabies' long incubation period, raising critical questions about timing of exposure versus vaccination and reinforcing why rabies surveillance and prevention remains essential.
• ​Moderna secured $54 million in funding from the Coalition for Epidemic Preparedness Innovations (CEPI) to put toward its experimental avian influenza mRNA vaccine for humans, and must reserve 20% of its production capacity for low and middle income countries.
• January is One Health Month, offering opportunities for veterinarians, pet owners, and the public to engage in education, advocacy, and collaboration to protect people, animals, and the environment.

Pet owners and veterinary professionals, sign up for our newsletter here: https://www.yourvetwantsyoutoknow.com/newsletter

Veterinarians are invited to join the American Association of Food Safety and Public Health Veterinarians.

Help support our mission through BUY ME A COFFEE: https://buymeacoffee.com/yourvet

Our vision is for Your Vet Wants You to Know to be a resource for veterinarians to improve client communication by introducing a discussion about a common topic during the vet visit, then directing the client to a reliable source of engaging, understandable, and accessible information.

By doing so, we strive for: 1) increased pet health literacy among pet owners, 2) improved partnership between clients and the veterinary team, 3) improved medical outcomes for pets, and 4) improved quality of life and efficiency for veterinarians.

Connect with Your Vet! Instagram: https://www.instagram.com/yourvetwantsyoutoknow Facebook: https://www.facebook.com/yourvetwantsyoutoknow Facebook group: https://www.facebook.com/groups/yourvetwantsyoutoknow

In Part 3 of Mission RENAL, a series on Chronic Kidney Disease (CKD) in pets, Dr. JD Foster, small animal internal medicine and nephrology expert joins to explain ways cat and dog owners can help support their pet with chronic kidney disease at home through nutrition, hydration, and monitoring. Sponsored by Royal Canin and Elanco, this guide empowers pet owners with Real Education for Navigating Advanced Longevity in dogs and cats with chronic kidney disease.

• Prescription renal diets significantly improve survival and quality of life.

• Encourage hydration through food, fountains, and flavor additives.

• Subcutaneous fluids should be reserved for when other methods fail.

• Create a prioritized medication plan with your veterinarian.

• Regular rechecks every 3–4 months help catch issues early.

• Celebrate small wins — joy and connection matter as much as lab numbers.

Resources & Links:

• Episode page with pictures and video: Mission RENAL Part 3: Home Care for Pet with Chronic Kidney Disease

• Find a veterinary internal medicine specialist near you: Specialist Search Here

Our vision is for Your Vet Wants You to Know to be a resource for veterinarians to improve client communication by introducing a discussion about a common topic during the vet visit, then directing the client to a reliable source of engaging, understandable, and accessible information.

By doing so, we strive for: 1) increased pet health literacy among pet owners, 2) improved partnership between clients and the veterinary team, 3) improved medical outcomes for pets, and 4) improved quality of life and efficiency for veterinarians.

Help support our mission through BUY ME A COFFEE: https://buymeacoffee.com/yourvet

Connect with Your Vet! Instagram: https://www.instagram.com/yourvetwantsyoutoknow Facebook: https://www.facebook.com/yourvetwantsyoutoknow Facebook group: https://www.facebook.com/groups/yourvetwantsyoutoknow

Mission RENAL is sponsored by Royal Canin and Elanco™ makers of VarenzinTM-CA1 (molidustat oral suspension).

Varenzin-CA1 is indicated for the control of nonregenerative anemia associated with chronic kidney disease (CKD) in cats.

Important Safety Information

Varenzin-CA1 is for oral use in cats only and prescribed only by licensed veterinarians. Keep this drug and used syringes out of reach of children. Wash hands immediately after use. In case of accidentally swallowing, call a doctor immediately. Women who are or may become pregnant should use the product with caution. Do not give to pregnant, nursing or breeding cats. Before using Varenzin-CA1, talk to your veterinarian if your cat is allergic to molidustat, has a history of seizures or thromboembolic disease predisposition. Use with caution in cats younger than 1 year of age. Common side effects include vomiting and high blood pressure. Red blood cell proportion should be monitored. Click here for complete safety information.

In this One Health Heroes update, Dr. Mandy Sorensen, communication specialist with the American Association of Food Safety and Public Health Veterinarians, discusses:

• ​Avian influenza is now widespread across the U.S., affecting wild birds, backyard flocks, commercial poultry, and even dairy herds, underscoring the need for continued surveillance and reporting.
• ​Wildlife impacts are profound, with avian influenza linked to catastrophic population losses in Southern elephant seals, highlighting the broader biodiversity consequences of emerging diseases.
• ​Vaccine hesitancy is increasing among pet owners, with studies estimating hesitancy in ~21% of dog owners and ~25% of cat owners, mirroring trends seen in human medicine.
• ​Rabies remains a fatal but preventable disease, with recent cases illustrating how small wildlife exposures (including bats and skunks) can lead to tragic outcomes in both animals and humans.
• Canine parvovirus is resurging in some areas, causing severe, often fatal disease in unvaccinated puppies—reinforcing the importance of routine vaccination and herd protection.

Pet owners and veterinary professionals, sign up for our newsletter here: https://www.yourvetwantsyoutoknow.com/newsletter

Veterinarians are invited to join the American Association of Food Safety and Public Health Veterinarians.

Help support our mission through BUY ME A COFFEE: https://buymeacoffee.com/yourvet

Our vision is for Your Vet Wants You to Know to be a resource for veterinarians to improve client communication by introducing a discussion about a common topic during the vet visit, then directing the client to a reliable source of engaging, understandable, and accessible information.

By doing so, we strive for: 1) increased pet health literacy among pet owners, 2) improved partnership between clients and the veterinary team, 3) improved medical outcomes for pets, and 4) improved quality of life and efficiency for veterinarians.

Connect with Your Vet! Instagram: https://www.instagram.com/yourvetwantsyoutoknow Facebook: https://www.facebook.com/yourvetwantsyoutoknow Facebook group: https://www.facebook.com/groups/yourvetwantsyoutoknow

In Part 2 of Mission RENAL, a series on Chronic Kidney Disease (CKD) in pets, Dr. JD Foster, small animal internal medicine and nephrology expert joins to explain how veterinarians interpret blood and urine tests to diagnose kidney disease, what IRIS staging means, and the importance of individualized treatment plans. Sponsored by Royal Canin and Elanco, this guide empowers pet owners with Real Education for Navigating Advanced Longevity in dogs and cats with chronic kidney disease.

Key Takeaways:

• Blood and urine tests together give the most accurate picture of kidney health.

• IRIS staging helps veterinarians guide treatment but doesn't define your pet's prognosis.

• Rechecks every 3–4 months (or more often if unstable) help maintain your pet's quality of life.

• Discuss lab results with your veterinarian—context matters more than red numbers.

• Each pet's journey is unique; don't rely on internet timelines or myths.

• Early detection saves lives. Routine screening can catch CKD before symptoms appear.

Resources & Links:

• Episode page with pictures and video: Mission RENAL Part 2: Tests and Staging Chronic Kidney Disease in Pets

• Find a veterinary internal medicine specialist near you: Specialist Search Here

Our vision is for Your Vet Wants You to Know to be a resource for veterinarians to improve client communication by introducing a discussion about a common topic during the vet visit, then directing the client to a reliable source of engaging, understandable, and accessible information.

By doing so, we strive for: 1) increased pet health literacy among pet owners, 2) improved partnership between clients and the veterinary team, 3) improved medical outcomes for pets, and 4) improved quality of life and efficiency for veterinarians.

Help support our mission through BUY ME A COFFEE: https://buymeacoffee.com/yourvet

Connect with Your Vet! Instagram: https://www.instagram.com/yourvetwantsyoutoknow Facebook: https://www.facebook.com/yourvetwantsyoutoknow Facebook group: https://www.facebook.com/groups/yourvetwantsyoutoknow

Mission RENAL is sponsored by Royal Canin and Elanco™ makers of VarenzinTM-CA1 (molidustat oral suspension).

Varenzin-CA1 is indicated for the control of nonregenerative anemia associated with chronic kidney disease (CKD) in cats.

Important Safety Information

Varenzin-CA1 is for oral use in cats only and prescribed only by licensed veterinarians. Keep this drug and used syringes out of reach of children. Wash hands immediately after use. In case of accidentally swallowing, call a doctor immediately. Women who are or may become pregnant should use the product with caution. Do not give to pregnant, nursing or breeding cats. Before using Varenzin-CA1, talk to your veterinarian if your cat is allergic to molidustat, has a history of seizures or thromboembolic disease predisposition. Use with caution in cats younger than 1 year of age. Common side effects include vomiting and high blood pressure. Red blood cell proportion should be monitored. Click here for complete safety information.

In this One Health Heroes update, Dr. Mandy Sorensen, communication specialist with the American Association of Food Safety and Public Health Veterinarians, discusses:

• The first reported human fatality from H5N5 avian influenza in Washington State, how this strain differs from the widely circulating H5N1 affecting poultry, wild birds, and cattle, and why mutations remain a growing public health concern.
• An update on New World Screwworm, including the launch of the new federal website and ongoing federal surveillance efforts near the southern U.S. border.
• Holiday food safety and pet safety tips, focusing on preventing food-borne illness, safe meat preparation, household hazards, and reducing holiday stress for pets.

Pet owners and veterinary professionals, sign up for our newsletter here: https://www.yourvetwantsyoutoknow.com/newsletter

Veterinarians are invited to join the American Association of Food Safety and Public Health Veterinarians.

Help support our mission through BUY ME A COFFEE: https://buymeacoffee.com/yourvet

Our vision is for Your Vet Wants You to Know to be a resource for veterinarians to improve client communication by introducing a discussion about a common topic during the vet visit, then directing the client to a reliable source of engaging, understandable, and accessible information.

By doing so, we strive for: 1) increased pet health literacy among pet owners, 2) improved partnership between clients and the veterinary team, 3) improved medical outcomes for pets, and 4) improved quality of life and efficiency for veterinarians.

Connect with Your Vet! Instagram: https://www.instagram.com/yourvetwantsyoutoknow Facebook: https://www.facebook.com/yourvetwantsyoutoknow Facebook group: https://www.facebook.com/groups/yourvetwantsyoutoknow

In Part 1 of Mission RENAL, a series on Chronic Kidney Disease (CKD) in pets, Dr. JD Foster, small animal internal medicine and nephrology expert joins to explain the difference between Acute Kidney Injury (AKI) and CKD, why many CKD cases have no single cause, the early warning signs and why these signs happen, the power of early screening to slow progression, and how staging CKD guides individualized care.

• CKD is irreversible but manageable—early detection matters.

• PU/PD (peeing/drinking more) is often the first clue; appetite changes are common.

• Pets can act normal with substantial kidney function loss—don't wait on labs.

• Wellness bloodwork + urinalysis help slow the disease early.

• Staging organizes care so your pet gets the right support at the right time.

Resources & Links:

• Episode page with pictures and video: Mission RENAL Part 1: Understanding Chronic Kidney Disease in Pets

• Find a veterinary internal medicine specialist near you: Specialist Search Here

Our vision is for Your Vet Wants You to Know to be a resource for veterinarians to improve client communication by introducing a discussion about a common topic during the vet visit, then directing the client to a reliable source of engaging, understandable, and accessible information.

By doing so, we strive for: 1) increased pet health literacy among pet owners, 2) improved partnership between clients and the veterinary team, 3) improved medical outcomes for pets, and 4) improved quality of life and efficiency for veterinarians.

Help support our mission through BUY ME A COFFEE: https://buymeacoffee.com/yourvet

Connect with Your Vet! Instagram: https://www.instagram.com/yourvetwantsyoutoknow Facebook: https://www.facebook.com/yourvetwantsyoutoknow Facebook group: https://www.facebook.com/groups/yourvetwantsyoutoknow

Mission RENAL is sponsored by Royal Canin and Elanco™ makers of VarenzinTM-CA1 (molidustat oral suspension).

Varenzin-CA1 is indicated for the control of nonregenerative anemia associated with chronic kidney disease (CKD) in cats.

Important Safety Information

Varenzin-CA1 is for oral use in cats only and prescribed only by licensed veterinarians. Keep this drug and used syringes out of reach of children. Wash hands immediately after use. In case of accidentally swallowing, call a doctor immediately. Women who are or may become pregnant should use the product with caution. Do not give to pregnant, nursing or breeding cats. Before using Varenzin-CA1, talk to your veterinarian if your cat is allergic to molidustat, has a history of seizures or thromboembolic disease predisposition. Use with caution in cats younger than 1 year of age. Common side effects include vomiting and high blood pressure. Red blood cell proportion should be monitored. Click here for complete safety information.