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NASA astronauts are poised to lift off Wednesday on a 10-day journey that will slingshot them around the moon, marking humanity’s return to the lunar vicinity for the first time in more than half a century.

The crew’s Lockheed Martin Corp.-built Orion capsule, perched atop the Boeing Co.-made Space Launch System rocket, is set to launch at 6:24 p.m. local time from Kennedy Space Center in Florida.

The mission is a crucial, in-space dress rehearsal for the long-delayed SLS rocket and Orion capsule, and marks the biggest milestone yet in NASA’s multi-year Artemis campaign to land humans on the moon as soon as 2028. If the mission launches on schedule, the four-person crew will travel farther in space than anyone in history.

President Donald Trump’s NASA administrator, Jared Isaacman, and former astronaut and US Senator Mark Kelly attended the send-off.Earlier, European Space Agency Director General Josef Aschbacher joined other NASA officials, lawmakers and industry executives walking the press site, conducting interviews. TV outlets set up white tents on the lawn outside to capture the giant SLS rocket standing a few miles away.
Today's show features:

• Ed Ludlow, Bloomberg Tech Co-Host on NASA's Artemis II Launch
• Rebecca Homkes, Lecturer at the London Business School and Faculty at Duke Corporate Executive Education
• Andrew Szczurowski, Morgan Stanley Investment Management Strategic Income Portfolio Manager
• Ben Gagnon, Bitfarms CEO on Bitfarms Officially Rebrands as Keel Infrastructure; Completes U.S. Redomiciliation

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