NeuroFrontiers

Amyloid-related imaging abnormalities (ARIA) represent a critical challenge in the management of Alzheimer's disease (AD), requiring a collaborative, interdisciplinary approach. This program, "Clinical Conundrums: Navigating Case Scenarios in Your Own Practice Setting," offers healthcare professionals concise, case-based microlearning episodes—each approximately 5 minutes long—designed to fit seamlessly into busy schedules. With real-world scenarios and expert-led discussions, this activity provides practical strategies to address diagnostic, monitoring, and therapeutic considerations, equipping participants to optimize patient care and outcomes in their respective fields.

Amyloid-related imaging abnormalities (ARIA) represent a critical challenge in the management of Alzheimer's disease (AD), requiring a collaborative, interdisciplinary approach. This program, "Clinical Conundrums: Navigating Case Scenarios in Your Own Practice Setting," offers healthcare professionals concise, case-based microlearning episodes—each approximately 5 minutes long—designed to fit seamlessly into busy schedules. With real-world scenarios and expert-led discussions, this activity provides practical strategies to address diagnostic, monitoring, and therapeutic considerations, equipping participants to optimize patient care and outcomes in their respective fields.

Amyloid-related imaging abnormalities (ARIA) represent a critical challenge in the management of Alzheimer's disease (AD), requiring a collaborative, interdisciplinary approach. This program, "Clinical Conundrums: Navigating Case Scenarios in Your Own Practice Setting," offers healthcare professionals concise, case-based microlearning episodes—each approximately 5 minutes long—designed to fit seamlessly into busy schedules. With real-world scenarios and expert-led discussions, this activity provides practical strategies to address diagnostic, monitoring, and therapeutic considerations, equipping participants to optimize patient care and outcomes in their respective fields.

While multiple kinds of animal models are commonly used to study multiple sclerosis (MS), they are not always ideal for getting the full picture of the disease. To address these gaps, a new CAR T-cell-based model provides a reproducible disease course, discrete lesion formation, and an improved platform for testing remyelination therapies. Dr. Christian Cordano, Associate Researcher of Neurology at the University of California, San Francisco Weill Institute for Neurosciences, explains how this approach aims to overcome key limitations of traditional research models for MS. Dr. Cordano also spoke on this topic at the ACTRIMS Forum 2025.

A recent study examined the association between comorbidities, adverse events, and early trial discontinuation in phase III clinical trials for disease-modifying therapies for multiple sclerosis. Join Dr. Amber Salter as she explains her findings and implications for clinical practice, including personalized treatment approaches. Dr. Salter is an Associate Professor of Biostatistics at UT Southwestern Medical Center, and she presented on this research at the ACTRIMS Forum 2025.

A recent study found that a ketogenic diet may have anti-inflammatory effects in patients with multiple sclerosis (MS), potentially reducing relapse risk. However, this diet also comes with a variety of risks and challenges. Hear from Dr. Michael Kornberg as he explains the potential benefits and drawbacks of this approach. Dr. Kornberg is an Assistant Professor of Neurology at Johns Hopkins University School of Medicine, and he presented on this topic at the ACTRIMS Forum 2025.

Prodromal symptoms are common in neurologic and inflammatory conditions like multiple sclerosis (MS). Recent evidence suggests that prodromal symptoms also exist in patients with neuromyelitis optica spectrum disorder (NMOSD) and MOG antibody disease (MOGAD). Join Dr. Dalia Rotstein as she explains how emerging research is providing insight into these symptoms, potentially informing our diagnostic strategies.

To address the concerning effects of demyelinating events in patients with multiple sclerosis (MS), a recent study explored whether neuromodulation could support myelin repair and restoration of function. Learn more as Dr. Cristin Welle explains how vagus nerve stimulation has the potential to play a role in remyelination. Dr. Cristin Welle is a Professor of Neurosurgery and Physiology at the University of Colorado Anschutz Medical Campus, and she spoke about this topic at the ACTRIMS Forum 2025.

In patients with multiple sclerosis, lesions in white matter can disrupt brain connectivity, leading to cognitive and motor impairments. Join Dr. Amy Kuceyeski as she discusses the pathophysiology behind structural disconnectivity and shares insights on new tools being developed to more accurately identify it in patients with multiple sclerosis. Dr. Kuceyeski is a Professor of Mathematics in Radiology and Neuroscience at Weill Cornell Medicine, and she spoke on this topic at the ACTRIMS Forum 2025.

Respiratory complications are fairly common in patients with neuromuscular disorders, and given their vast impacts on a patient’s prognosis and quality of life, it’s critical to proactively detect and monitor any signs of respiratory decline. To learn more about the symptoms, impacts, and diagnosis of respiratory complications in patients with neuromuscular disorders, Dr. Charles Turck speaks with Dr. Jason Ackrivo. Not only is Dr. Ackrivo the Associate Director of the Fishman Program for Home Assisted Ventilation, but he's also an Assistant Professor of Medicine in Pulmonary, Allergy, and Critical Care at the Hospital of the University of Pennsylvania.