In part one of this three-part series, Dr. Justin Abbatemarco and Dr. Jiwon Oh discuss how Bruton Tyrosine Kinase (BTK) Inhibitors work and how they vary from other disease-modifying therapies. 

Show reference:

https://www.nejm.org/doi/full/10.1056/NEJMoa2415985 

https://www.nejm.org/doi/full/10.1056/NEJMoa2415988 

Dr. Justin Abbatemarco provides an update on autologous hematopoietic stem cell transplantation in multiple sclerosis.

Show reference:

https://www.nature.com/articles/s41582-024-01050-x

In this women's history minute, Dr. Alison Christy discusses the life and legacy of Mary A. B. Brazier.

In part two of this two-part series, Dr. Jeff Ratliff and Dr. Harry Sutherland discuss the diverse strategies that residency programs implement to ensure residents can continue their education in a protected and supportive environment. 

Show reference:

https://www.neurology.org/doi/10.1212/NE9.0000000000200205 

In part one of this two-part series, Dr. Jeff Ratliff and Dr. Harry Sutherland discuss how neurology residency programs are incorporating didactic teaching methods to enhance learning outside the clinical environment.

Show reference:

https://www.neurology.org/doi/10.1212/NE9.0000000000200205 

Dr. Jessica Ailani and Dr. Richard B. Lipton discuss the significance of recognizing prodromal symptoms, the findings from the PRODROME trial, and the implications for clinical practice. 

Show reference:

https://www.neurology.org/doi/10.1212/CPJ.0000000000200359 

Dr. Tesha Monteith discusses an abstract that was presented at the AAN Annual Meeting titled, “Estrogen Exposure from Modern Hormonal Contraceptives and Vascular Risk in Women with Migraine: A Nationwide Electronic Health Record Database Study.”

Show reference: 

https://index.mirasmart.com/AAN2025/PDFfiles/AAN2025-002306.html 

In the final episode of this four-part series, Dr. Justin Abbatemarco and Dr. Nancy Newman discuss the abstract she presented at the AAN Annual Meeting and details on the upcoming gene therapy trial. 

Show reference:

https://www.neurology.org/doi/10.1212/WNL.0000000000208987 

Prof. Jon Stone, Dr. Laura Strom, and Meagan Watson discuss functional seizures and healthcare costs related to the functional seizure program at the University of Colorado.

Show reference:

https://www.neurology.org/doi/10.1212/CPJ.0000000000200393 

Neurology® Open Access has officially launched! 

In part two of this two-part series, Dr. Jeff Ratliff and Dr. Amy C. Kunchok discuss the advantages of an open-access publication model.

Read the related editorial in Neurology® Open Access.