TWiN reveals that proteins travel from the blood to the brain where they are taken up by microglia, revealing a new mode of communication between the brain and the periphery.

Hosts: Vincent Racaniello, Tim Cheung, and Vivianne Morrison

Subscribe (free): Apple Podcasts, Google Podcasts, RSS

Links for this episode

• MicrobeTV Discord Server
• Circulatory proteins taken up by brain microglia (bioRxiv)
• Timestamps by Jolene Ramsey. Thanks!

Music is by Ronald Jenkees

Send your neuroscience questions and comments to [email protected]

TWiN discusses experiments which show that high-fidelity memories that lose their precision with time depends on reorganization of hippocampal circuitry.

Hosts: Vincent Racaniello, Jason Shepherd, and Tim Cheung

Subscribe (free): Apple Podcasts, Google Podcasts, RSS

Links for this episode

• MicrobeTV Discord Server
• Loss of precision memory and the hippocampus (Nature)
• Changes in hippocampi of cab drivers (PNAS)
• Timestamps by Jolene Ramsey. Thanks!

Music is by Ronald Jenkees

Send your neuroscience questions and comments to [email protected]

Tim explains AI co-scientist, a tool released by Google, which it hopes to help scientists generate hypotheses and research proposals, and to accelerate the speed of scientific and biomedical discoveries.

Hosts: Vincent Racaniello, Tim Cheung, and Vivianne Morrison

Subscribe (free): Apple Podcasts, Google Podcasts, RSS

Links for this episode

• MicrobeTV Discord Server
• AI cracks superbug problem (BBC)
• Accelerating scientific breakthroughs (Google Research)
• Towards an AI co-scientist (arXiv)
• Timestamps by Jolene Ramsey. Thanks!

Music is by Ronald Jenkees

Send your neuroscience questions and comments to [email protected]

TWiN explains a study showing that when a mouse is confronted with an unconscious conspecific, it engages in behavior including tongue-dragging to resuscitate the animal via a tongue-brain connection.

Hosts: Vincent Racaniello, Tim Cheung, and Vivianne Morrison

Subscribe (free): Apple Podcasts, Google Podcasts, RSS

Links for this episode

• MicrobeTV Discord Server
• Tongue-dragging in mice (Sci Adv)
• Timestamps by Jolene Ramsey. Thanks!

Music is by Ronald Jenkees

Send your neuroscience questions and comments to [email protected]

TWiN discusses a study showing that repetitive injury reactivates HSV-1 in a human brain tissue model and induces phenotypes associated with Alzheimer’s disease.

Hosts: Vincent Racaniello and Tim Cheung

Subscribe (free): Apple Podcasts, Google Podcasts, RSS

Links for this episode

• MicrobeTV Discord Server
• Repetitive injury, herpes, and Alzheimers (Sci Signal)
• The tau of herpesvirus (TWiV 1187)
• Fishing for viruses in senile (TWiV 519)
• Timestamps by Jolene Ramsey. Thanks!

Music is by Ronald Jenkees

Send your neuroscience questions and comments to [email protected]

TWiN explains a study showing that while groups of neurons, form the basis for memory, astrocytes are key components of the adaptive reponse to learning experiences, and regulate the flow of information during circuit plasticity and memory recall.

Hosts: Vincent Racaniello, Jason Shepherd, and Tim Cheung

Subscribe (free): Apple Podcasts, Google Podcasts, RSS

Links for this episode

• MicrobeTV Discord Server
• Write your Senator, oppose RFK Jr nomination
• Astrocytes and memory (Nature)
• Timestamps by Jolene. Thanks!

Music is by Ronald Jenkees

Send your neuroscience questions and comments to [email protected]

TWiN explains the identification of a brain circuit and periodic branch-specific neurotransmitter deployment that regulates organismal adaptation to photoperiod change.

Hosts: Vincent Racaniello, Jason Shepherd, and Tim Cheung

Subscribe (free): Apple Podcasts, Google Podcasts, RSS

Links for this episode

• MicrobeTV Discord Server
• Brain circuit for photoperiod adaptation (Nature)
• Timestamps by Jolene. Thanks!

Music is by Ronald Jenkees

Send your neuroscience questions and comments to [email protected]

TWiN explores how pregnancy leads to modifications in brain structure and function that may prepare the mother for parenting.

Hosts: Vincent Racaniello, Jason Shepherd, and Vivianne Morrison

Subscribe (free): Apple Podcasts, Google Podcasts, RSS

Links for this episode

• MicrobeTV Discord Server
• Pregnancy transforms the brain (Nature)
• Hormone-mediated neural remodeling during pregnancy (Science)
• Effects of pregnancy on brain activity (Nature Comm)
• Timestamps by Jolene. Thanks!

Music is by Ronald Jenkees

Send your neuroscience questions and comments to [email protected]

Joseph Paton and Felipe Rodrigues join TWiN to explain how they used temperature manipulation to alter the speed of neuronal dynamics in the dorsal striatum of rats, a manipulation that selectively slowed down or sped up time perception, illuminating the mechanisms of time-based decisions.

Hosts: Vincent Racaniello, Jason Shepherd, Timothy Cheung, and Vivianne Morrison

Guest: Joseph J. Paton and Felipe Rodrigues

Subscribe (free): Apple Podcasts, Google Podcasts, RSS

Links for this episode

• MicrobeTV Discord Server
• Using temperature to analyze the neural basis of a time-based decision (Nat Neurosci)
• Hot times for the dorsal striatum (Nat Neurosci)
• Timestamps by Jolene. Thanks!

Music is by Ronald Jenkees

Send your neuroscience questions and comments to [email protected]

Mauro Costa-Mattioli returns to TWiN to discuss the results of a placebo controlled, double blind clinical trial of a probiotic which improved social behavior but not autism severity in children with ASD.

Hosts: Jason Shepherd, Timothy Cheung, and Vivianne Morrison

Guest: Mauro Costa-Mattioli

Subscribe (free): Apple Podcasts, Google Podcasts, RSS

Links for this episode

• MicrobeTV Discord Server
• Probiotics for autism spectrum disorder (Cell Host Microbe)
• Timestamps by Jolene. Thanks!

Music is by Ronald Jenkees

Send your neuroscience questions and comments to [email protected]