In this episode, Nathan Labenz speaks with Vivek Natarajan and Anil Palepu from Google DeepMind about their groundbreaking work on AMIE (Articulate Medical Intelligence Explorer) and Co-Scientist. The conversation reveals how these AI systems are already outperforming human physicians in diagnostic accuracy and treatment recommendations, with AMIE now entering clinical trials at a Harvard Medical School teaching hospital. Even more remarkably, the Co-Scientist system demonstrates genuine scientific discovery capabilities, independently proposing the exact same mechanism for bacterial drug resistance that human scientists had recently discovered but not yet published—signaling a threshold moment where AI is becoming a legitimate thought partner in humanity's most complex intellectual endeavors.

SPONSORS:

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CHAPTERS:

(00:00) About the Episode

(06:26) Introduction and Welcome

(07:49) AMY Medical Intelligence Overview

(11:29) Chat-Based Medical Interactions

(13:59) Specialized Medicine Results

(18:17) Co-Scientist System Headlines (Part 1)

(18:21) Sponsors: Oracle Cloud Infrastructure (OCI) | Shopify

(21:36) Co-Scientist System Headlines (Part 2)

(26:32) Bacterial Drug Resistance Discovery

(31:41) AI Scientific Discovery Process

(35:35) Hallucinations vs. Creativity (Part 1)

(35:37) Sponsors: NetSuite

(37:10) Hallucinations vs. Creativity (Part 2)

(42:04) Agent Design Architecture

(49:17) Long Context Benefits

(55:35) Computational Requirements

(01:01:10) Specialist Models Integration

(01:07:01) Future Model Integration

(01:12:31) Tournament Evaluation Methods

(01:19:09) AI Question Generation

(01:22:42) Real-World Deployment Plans

(01:25:58) Outro